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12 p, 2.4 MB δ Opioid receptor agonism preserves the retinal pigmented epithelial cell tight junctions and ameliorates the retinopathy in experimental diabetes / De Faria, J. M. L. (Renal Pathophysiology Laboratory Investigation on Diabetes Complications. Faculty of Medical Sciences. State University of Campinas (UNICAMP)) ; Duarte, D. A. (Renal Pathophysiology Laboratory Investigation on Diabetes Complications. Faculty of Medical Sciences. State University of Campinas (UNICAMP)) ; Simó, R. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia-Ramírez, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Dátilo, M. N. (Renal Pathophysiology Laboratory Investigation on Diabetes Complications. Faculty of Medical Sciences. State University of Campinas (UNICAMP)) ; Pasqualetto, F. C. (Renal Pathophysiology Laboratory Investigation on Diabetes Complications. Faculty of Medical Sciences. State University of Campinas (UNICAMP)) ; De Faria, J. B. L. (Renal Pathophysiology Laboratory Investigation on Diabetes Complications. Faculty of Medical Sciences. State University of Campinas (UNICAMP)) ; Universitat Autònoma de Barcelona
PURPOSE. Outer blood retinal barrier breakdown is a neglected feature of diabetic retinopathy (DR). We demonstrated that the agonism of the δ opioid receptor (DOR) by epicatechin preserves the tight junction proteins in ARPE-19 cells under diabetic conditions. [...]
2019 - 10.1167/iovs.19-26761
Investigative Ophthalmology & Visual Science, Vol. 60 Núm. 12 (january 2019) , p. 3842-3853  

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1 Pasqualetto, F. C.
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