Pazdernik, Vanessa - Resultados de la búsqueda - Depósito Digital de Documentos de la UAB

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Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes / Toikumo, Sylvanus (University of Pennsylvania Perelman School of Medicine) ; Jennings, Mariela V (University of California San Diego) ; Pham, Benjamin K (University of California San Diego) ; Lee, Hyunjoon (Massachusetts General Hospital) ; Mallard, Travis T (Harvard Medical School) ; Bianchi, Sevim B (University of California San Diego) ; Meredith, John J (University of California San Diego) ; Vilar-Ribó, L (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Xu, Heng (University of California San Diego) ; Hatoum, Alexander S (Washington University School of Medicine) ; Johnson, Emma C (Washington University School of Medicine) ; Pazdernik, Vanessa (Mayo Clinic) ; Jinwala, Zeal (University of Pennsylvania Perelman School of Medicine) ; Pakala, Shreya R (University of California San Diego) ; Leger, Brittany S (University of California San Diego) ; Niarchou, Maria (Vanderbilt Genetics Institute) ; Ehinmowo, Michael (University of Ibadan) ; Jenkins, Greg D (Mayo Clinic) ; Batzler, Anthony (Mayo Clinic) ; Pendegraft, Richard (Mayo Clinic) ; Palmer, Abraham A (University of California San Diego) ; Zhou, Hang (Veterans Affairs Connecticut Healthcare System) ; Biernacka, Joanna M (Mayo Clinic) ; Coombes, Brandon J (Mayo Clinic) ; Gelernter, Joel (Veterans Affairs Connecticut Healthcare System) ; Xu, Ke (Veterans Affairs Connecticut Healthcare System) ; Hancock, Dana B (RTI International) ; Cox, Nancy J (Vanderbilt University) ; Smoller, Jordan W (Harvard Medical School) ; Davis, Lea K (Vanderbilt University Medical Center) ; Justice, Amy C (Yale University School of Medicine) ; Kranzler, Henry R (University of Pennsylvania Perelman School of Medicine) ; Kember, Rachel L (University of Pennsylvania Perelman School of Medicine) ; Sanchez-Roige, Sandra (Vanderbilt University) ; Universitat Autònoma de Barcelona
Tobacco use disorder (TUD) is the most prevalent substance use disorder in the world. Genetic factors influence smoking behaviors, and although strides have been made using genome-wide association studies (GWAS) to identify risk variants, the majority of variants identified have been for nicotine consumption, rather than TUD. [...]
2023 - DOI (Digital Object Identifier)

10.1101/2023.03.27.23287713
medRxiv, september 2023

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