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19 p, 4.8 MB Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats / Patricio, Felipe (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ; Morales Dávila, Eliud (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ; Patricio-Martínez, Aleidy (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ; Arana Del Carmen, Nayeli (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ; Martínez, Isabel (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ; Aguilera, José (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Perez-Aguilar, Jose Manuel (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic)) ; Limón, Ilhuicamina Daniel (Benemérita Universidad Autónoma de Puebla (Puebla, Mèxic))
Cannabidiol (CBD) presents antiparkinsonian properties and neuromodulatory effects, possibly due to the pleiotropic activity caused at multiple molecular targets. Recently, the GPR55 receptor has emerged as a molecular target of CBD. [...]
2022 - 10.3389/fphar.2022.945836
Frontiers in Pharmacology, Vol. 13 (september 2022)  
Detailed record - Creative Commons

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