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52 p, 705.6 KB Role of Amyloid-β and Tau Proteins in Alzheimer's Disease : Confuting the Amyloid Cascade / Gulisano, W. (Department of Biomedical and Biotechnological Sciences. Section of Physiology. University of Catania) ; Maugeri, Daniele (Department of Biomedical and Biotechnological Sciences. Section of Physiology. University of Catania) ; Baltrons Soler, Ma. Antonia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Fà, Mauro (Taub Institute for Research on Alzheimer's Disease and the Aging Brain. Department of Medicine. Columbia University) ; Amato, Arianna (Department of Anaesthesiology. Università Cattolica Del Sacro Cuore) ; Palmeri, Agostino (Department of Biomedical and Biotechnological Sciences. Section of Physiology. University of Catania) ; D'Adamio, Luciano (Department of Pharmacology. Physiology and Neuroscience. Rutgers University) ; Grassi, Claudio (Institute of Human Physiology. Università Cattolica Del Sacro Cuore) ; Devanand, D.P. (Department of Psychiatry. Columbia University. College of Phys. and Surg.) ; Honig, Lawrence S. (Department of Neurology. Columbia University. College of Phys. and Surg.) ; Puzzo, Daniela (Department of Biomedical and Biotechnological Sciences. Section of Physiology. University of Catania) ; Arancio, Ottavio (Taub Institute for Research on Alzheimer's Disease and the Aging Brain. Department of Medicine. Columbia University)
The "Amyloid Cascade Hypothesis" has dominated the Alzheimer's disease (AD) field in the last 25 years. It posits that the increase of amyloid-β (Aβ) is the key event in AD that triggers tau pathology followed by neuronal death and eventually, the disease. [...]
2018 - 10.3233/JAD-179935
Journal of Alzheimer's disease, Vol. 64 Núm. s1 (2018) , p. S611-S631  
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1 Puzzo, D.
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