Ríos-Fernández, Raquel - Search Results - UAB Digital Repository of Documents

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12 p, 9.5 MB

Single-cell transcriptomic profiling reveals a pathogenic role of cytotoxic CD4+ T cells in giant cell arteritis / Carmona, Elio G. (Hospital Universitario San Cecilio (Granada)) ; Callejas Rubio, Jose Luis (Hospital Universitario San Cecilio (Granada)) ; Raya, Enrique (Hospital Universitario San Cecilio (Granada)) ; Ríos-Fernández, Raquel (Hospital Universitario San Cecilio (Granada)) ; Villanueva-Martín, Gonzalo (Institute of Parasitology and Biomedicine López-Neyra) ; Cid, María (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Hernández-Rodríguez, José (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Timmermann, Bernd (Max Planck Institute for Molecular Genetics) ; Ortego-Centeno, Norberto (Universidad de Granada. Departamento de Medicina) ; Martín, Javier (Spanish National Research Council) ; Márquez, Ana (Instituto de Parasitología y Biomedicina "López-Neyra")
Giant cell arteritis (GCA) is a systemic vasculitis mediated by an aberrant immunological response against the blood vessel wall. Although the pathogenic mechanisms that drive GCA have not yet been elucidated, there is strong evidence that CD4 T cells are key drivers of the inflammatory process occurring in this vasculitis. [...]
2024 - DOI (Digital Object Identifier)

10.1016/j.jaut.2023.103124
Journal of autoimmunity, Vol. 142 (january 2024) , p. 103124

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