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20 p, 1.8 MB Epigenetic regulation of B cells and its role in autoimmune pathogenesis / Xiao, Fan (Shenzhen Institute of Research and Innovation and Shenzhen Hospital. The University of Hong Kong. Hong Kong; Chongqing International Institute for Immunology) ; Rui, Ke (Institute of Medical Immunology. Affiliated Hospital of Jiangsu University) ; Shi, Xiaofei (Henan University of Science and Technology) ; Wu, Haijing (Second Xiangya Hospital. Central South University. Hunan Key Laboratory of Medical Epigenomics) ; Cai, Xiaoyan (Guangzhou First People's Hospital) ; Lui, Kathy O. (The Chinese University of Hong Kong) ; Lu, Qianjin (Second Xiangya Hospital. Central South University. Hunan Key Laboratory of Medical Epigenomics) ; Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Tian, Jie (Institute of Medical Immunology. Affiliated Hospital of Jiangsu University) ; Zou, Heijian (Huashan Hospital. Fudan University) ; Lu, Liwei (Centre for Oncology and Immunology. Hong Kong Science Park)
B cells play a pivotal role in the pathogenesis of autoimmune diseases. Although previous studies have shown many genetic polymorphisms associated with B-cell activation in patients with various autoimmune disorders, progress in epigenetic research has revealed new mechanisms leading to B-cell hyperactivation. [...]
2022 - 10.1038/s41423-022-00933-7
Cellular and Molecular Immunology, Vol. 19 Núm. 11 (november 2022) , p. 1215-1234  
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