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16 p, 657.0 KB Perspectives for systems biology in the management of tuberculosis / Kontsevaya, Irina (University of Lübeck) ; Lange, Christoph (University of Lübeck) ; Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Coarfa, Cristian (Baylor College of Medicine) ; DiNardo, Andrew R. (The Baylor College of Medicine) ; Gillespie, Stephen H. (University of St Andrew) ; Hauptmann, Matthias (Hamburg-Lübeck-Borstel-Riems) ; Leschczyk, Christoph (Hamburg-Lübeck-Borstel-Riems) ; Mandalakas, Anna M. (Baylor College of Medicine) ; Martinecz, Antal (Arctic University of Norway) ; Merker, Matthias (Hamburg-Lübeck-Borstel-Riems) ; Niemann, Stefan (Hamburg-Lübeck-Borstel-Riems) ; Reimann, Maja (University of Lübeck) ; Rzhepishevska, Olena (Umeå University (Suècia)) ; Schaible, Ulrich E. (Hamburg-Lübeck-Borstel-Riems) ; Scheu, Katrin M. (Research Center Borstel) ; Schurr, Erwin (Research Institute of the McGill University Health Centre (Montréal, Canada)) ; Abel zur Wiesch, Pia (Pennsylvania State University (Estats Units d'Amèrica)) ; Heyckendorf, Jan (University of Lübeck) ; Universitat Autònoma de Barcelona
Standardised management of tuberculosis may soon be replaced by individualised, precision medicine-guided therapies informed with knowledge provided by the field of systems biology. Systems biology is a rapidly expanding field of computational and mathematical analysis and modelling of complex biological systems that can provide insights into mechanisms underlying tuberculosis, identify novel biomarkers, and help to optimise prevention, diagnosis and treatment of disease. [...]
2021 - 10.1183/16000617.0377-2020
European Respiratory Review, Vol. 30 (may 2021)  

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