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9 p, 850.8 KB |
Intermittent hypoxia is associated with high hypoxia inducible factor-1α but not high vascular endothelial growth factor cell expression in tumors of cutaneous melanoma patients
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Almendros, Isaac (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Martínez-García, Miguel Ángel (Hospital Universitari i Politècnic La Fe (València)) ;
Campos-Rodríguez, Francisco (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Riveiro-Falkenbach, Erica (Hospital Universitario 12 de Octubre) ;
Rodríguez-Peralto, José L. (Hospital Universitario 12 de Octubre) ;
Nagore, Eduardo (Fundació Institut Valencià d'Oncologia) ;
Martorell-Calatayud, Antonio (Hospital de Manises (València)) ;
Blasco, Luis Hernández (Univ. Miguel Hernandez) ;
Roca, Jose Bañuls (Univ. Miguel Hernandez) ;
Vives, Eusebi Chiner (Hospital san Juan de Alicante) ;
Sánchez-de-la-Torre, Alicia (Hospital Universitari Arnau de Vilanova i Santa Maria) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montserrat Canal, José Ma (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Gil, Amalia (Hospital de Valme) ;
Cabriada-Nuño, Valentín (Hospital Universitario Cruces) ;
Cano-Pumarega, Irene (Hospital Universitario de Getafe) ;
Corral-Peñafiel, Jaime (Hospital Universitario S. Pedro Alcántara) ;
Diaz-Cambriles, Trinidad (Hospital 12 de Octubre (Madrid)) ;
Mediano, Olga (CIBER de enfermedades respiratorias) ;
Dalmau-Arias, Joan (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Farré, Ramón (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gozal, David (The University of Chicago) ;
Herrera, Elidia Molina (Hospital 12 de octubre) ;
García Martín, Rosa M. (Hospital 12 de octubre) ;
de Jaime, Maria Niveiro (Universidad Miguel Hernandez) ;
Moreno, Sara (Hospital Universitario Arnau de Vilanova) ;
Ilia, Ferran Barbé (Hospital Universitari Arnau de Vilanova i Santa Maria) ;
de la Torre, Manuel Sánchez (Hospital Universitari Arnau de Vilanova i Santa Maria) ;
de Eusebio, Esther (Hospital Universitario de Guadalajara) ;
Landete, Pedro (Instituto de Investigación Hospital Universitario de la Princesa) ;
Gordon, Manuel Moragón (Hospital Universitario) ;
Arias, Eva (Hospital 12 de Octubre (Madrid)) ;
Masa, Fernando (Hospital Universitario S. Pedro Alcántara) ;
Herrada, Carlos González (Hospital Universitario de Getafe) ;
Carrera, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Muñoz Ferrer, Aida (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Boada, Aram (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fortuna Gutiérrez, Ana Mª (Institut d'Investigació Biomèdica Sant Pau) ;
Mayos, Mercè (Institut d'Investigació Biomèdica Sant Pau) ;
García, Jesús Gardeazabal (Hospital Universitario Cruces) ;
Universitat Autònoma de Barcelona
Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) cell expression in the tumor and altered immune functions via intermittent hypoxia (IH). [...]
2018 -  10.3389/fneur.2018.00272
Frontiers in neurology, Vol. 9 Núm. APR (26 2018) , p. 272
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10 p, 1.1 MB |
Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome
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Zapater, Andrea (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Solelhac, Geoffroy (Lausanne University Hospital) ;
Sánchez-de-la-Torre, Alicia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Gracia-Lavedan, Esther (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Benitez, Ivan David (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Torres, Gerard (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
De Batlle, Jordi (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Haba-Rubio, José (Lausanne University Hospital) ;
Berger, Mathieu (Lausanne University Hospital) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Duran-Cantolla, Joaquín (Arabako Unibertsitate Ospitalea (Vitoria, País Basc)) ;
Urrutia, Amaia (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mediano, Olga (Hospital Universitario de Guadalajara) ;
Masdeu, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ordax-Carbajo, Estrella (Hospital Universitario de Burgos) ;
Masa, Juan Fernando (Hospital San Pedro de Alcántara) ;
De la Peña, Mónica (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Mayos, Mercè (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Coloma, Ramon (Complejo Hospitalario Universitario de Albacete) ;
Montserrat, Josep María (Hospital Clínic i Provincial de Barcelona) ;
Chiner, Eusebi (Hospital Universitari Sant Joan d'Alacant) ;
Mínguez, Olga (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Pascual, Lydia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Cortijo, Anunciación (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Martínez López, Dolores (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Dalmases, Mireia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Lee, Chi-Hang (National University of Singapore) ;
McEvoy, R. Doug (Flinders University) ;
Barbé, Ferran (University of Lausanne) ;
Heinzer, Raphael (University of Lausanne) ;
Sánchez-de-la-Torre, Manuel (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Universitat Autònoma de Barcelona
Obstructive sleep apnea (OSA) severity is based on the apnea-hypopnea index (AHI). The AHI is a simplistic measure that is inadequate for capturing disease severity and its consequences in cardiovascular diseases (CVDs). [...]
2022 - 10.3389/fmed.2022.870906
Frontiers in Medicine, Vol. 9 (june 2022)
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13 p, 1.3 MB |
Pulse Wave Amplitude Drops Index : A Biomarker of Cardiovascular Risk in Obstructive Sleep Apnea
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Solelhac, Geoffroy (Center for Investigation and Research in Sleep) ;
Sánchez-de-la-Torre, Manuel (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Blanchard, Margaux (Laboratoire d'Acoustique de l'Université du Mans) ;
Berger, Mathieu (Center for Investigation and Research in Sleep) ;
Hirotsu, Camila (Center for Investigation and Research in Sleep) ;
Imler, Théo (Center for Investigation and Research in Sleep) ;
Sánchez-de-la-Torre, Alicia (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Haba-Rubio, José (Center for Investigation and Research in Sleep) ;
Marchi, Nicola Andrea (Center for Investigation and Research in Sleep) ;
Bayon, Virginie (Center for Investigation and Research in Sleep) ;
Bailly, Sébastien (Université Grenoble Alpes) ;
Goupil, François (Le Mans General Hospital) ;
Waeber, Adrien (Center for Investigation and Research in Sleep) ;
Heiniger, Grégory (Center for Investigation and Research in Sleep) ;
Pigeanne, Thierry (Pôle santé des Olonnes) ;
Gracia-Lavedan, Esther (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Zapater, Andrea (Universitat de Lleida) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ordax, Estrella (Hospital Universitari de Burgos) ;
Masdeu, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cabriada-Nuño, Valentín (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Egea, Carlos (Instituto de Investigación Sanitaria Bioaraba (Vitoria, País Basc)) ;
Van Den Broecke, Sandra (Hôpital Neuchâtelois) ;
Vollenweider, Peter (Internal Medicine) ;
Marques-Vidal, Pedro (University of Lausanne) ;
Vaucher, Julien (Internal Medicine) ;
Bernardi, Giulio (IMT School for Advanced Studies) ;
Betta, Monica (IMT School for Advanced Studies) ;
Siclari, Francesca (The Sense Innovation and Research Center) ;
Barbé, Ferran (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Gagnadoux, Frédéric (University of Angers) ;
Heinzer, Raphael (Lausanne University Hospital) ;
Universitat Autònoma de Barcelona
It is currently unclear which patients with obstructive sleep apnea (OSA) are at increased cardiovascular risk. To investigate the value of pulse wave amplitude drops (PWADs), reflecting sympathetic activations and vasoreactivity, as a biomarker of cardiovascular risk in OSA. [...]
2023 - 10.1164/rccm.202206-1223OC
American Journal of Respiratory and Critical Care Medicine, Vol. 207 (april 2023) , p. 1620-1632
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12 p, 1000.3 KB |
Effect of patient sex on the severity of coronary artery disease in patients with newly diagnosis of obstructive sleep apnoea admitted by an acute coronary syndrome
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Sánchez de la Torre, Alicia (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Durán Cantolla, Joaquín (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Mediano, Olga (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Cabriada-Nuño, Valentín (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Masdeu, María José (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Terán, Joaquín (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Masa, Juan Fernando (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Peña, Mónica de la (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Aldomá, Albina (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Worner, Fernando (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Valls, Joan (Institut de Recerca Biomèdica de Lleida) ;
Barbé, Ferran (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Sánchez de la Torre, Manuel (Hospital Arnau de Vilanova (Lleida, Catalunya))
Background: The cardiovascular consequences of obstructive sleep apnoea (OSA) differ by sex. We hypothesized that sex influences the severity of acute coronary syndrome (ACS) in patients with OSA. OSA was defined as an apnoea-hypopnoea index (AHI).
2016 - 10.1371/journal.pone.0159207
PloS one, Vol. 11 Núm. 7 (July 2016)
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12 p, 237.9 KB |
Impact of Obstructive Sleep Apnea on the Levels of Placental Growth Factor (PlGF) and Their Value for Predicting Short-Term Adverse Outcomes in Patients with Acute Coronary Syndrome
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Barcelo Bennasar, Antonia (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Bauça, Josep Miquel (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Yáñez, Aina M (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Fueyo, Laura (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Gomez, Cristina (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
de la Peña, Monica (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Pierola, Javier (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Rodriguez, Alberto (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Sánchez-de-la-Torre, Manuel (Hospital Universitari Arnau de Vilanova and Santa Maria) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mediano, Olga (Hospital Universitario de Guadalajara) ;
Amilibia, Jose (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Masdeu, María José (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Teran, Joaquin (Hospital General Yagüe) ;
Montserrat Canal, José Ma (Hospital Clínic i Provincial de Barcelona) ;
Mayos, Mercè (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sanchez-De-La-Torre, Alicia (Hospital Universitari Arnau de Vilanova and Santa Maria) ;
Barbé, Ferran (Hospital Universitari Arnau de Vilanova and Santa Maria)
BACKGROUND: Placental growth factor (PlGF) induces angiogenesis and promotes tissue repair, and plasma PlGF levels change markedly during acute myocardial infarction (AMI). Currently, the impact of obstructive sleep apnea (OSA) in patients with AMI is a subject of debate. [...]
2016 - 10.1371/journal.pone.0147686
PloS one, Vol. 11 Núm. 3 (March 2016)
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