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14 p, 2.7 MB GPRC5C drives branched-chain amino acid metabolism in leukemogenesis / Zhang, Yu Wei (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Velasco-Hernández, Talia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mess, Julian (University of Freiburg) ; Lalioti, Maria Eleni (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Romero-Mulero, Mari Carmen (University of Freiburg, Germany) ; Obier, Nadine (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Karantzelis, Nikolaos (University Medical Center Freiburg, Germany) ; Rettkowski, Jasmin (University of Freiburg, Germany) ; Schönberger, Katharina (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Karabacz, Noemie (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Jäcklein, Karin (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Morishima, Tatsuya (Kumamoto University, Japan) ; Trincado Alonso, Juan Luis, 1987- (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Romecin, Paola (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martinez, Alba (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Takizawa, Hitoshi (Kumamoto University, Japan) ; Shoumariyeh, Khalid (University of Freiburg, Germany) ; Renders, Simon (Heidelberg University Hospital (Alemanya)) ; Zeiser, Robert (University of Freiburg, Germany) ; Pahl, Heike L. (University Medical Center Freiburg, Germany) ; Béliveau, François (Quebec leukemia cell bank. Hopital Maisonneuve-Rosemont, Montreal, Canada) ; Hébert, Josee (Quebec leukemia cell bank. Hopital Maisonneuve-Rosemont, Montreal, Canada) ; Lehnertz, Bernhard (University of Montreal, Canada) ; Sauvageau, Guy (University of Montreal, Canada) ; Menendez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Cabezas-Wallscheid, Nina (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany)
Leukemia stem cells (LSCs) share numerous features with healthy hematopoietic stem cells (HSCs). G-protein coupled receptor family C group 5 member C (GPRC5C) is a regulator of HSC dormancy. However, GPRC5C functionality in acute myeloid leukemia (AML) is yet to be determined. [...]
2023 - 10.1182/bloodadvances.2023010460
Blood advances, Vol. 7 Núm. 24 (december 2023) , p. 7525-7538  
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