Smith, K P. - Search Results - UAB Digital Repository of Documents

Search collections:

Sort by:	Display results:	Output format:

Results overview: Found 1 records in 0.02 seconds.
Articles, 1 records found

Articles	1 records found

11 p, 871.5 KB

Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors / Powers, R. K. (Department of Pharmacology. University of Colorado Anschutz Medical Campus) ; Culp-Hill, R. (Department of Biochemistry and Molecular Genetics. University of Colorado Anschutz Medical Campus) ; Ludwig, M. P. (Department of Pharmacology. University of Colorado Anschutz Medical Campus) ; Smith, K. P. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Waugh, K. A. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Minter, R. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Tuttle, K. D. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Lewis, H. C. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Rachubinski, A. L. (Department of Pediatrics. University of Colorado Anschutz Medical Campus) ; Granrath, R. E. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ; Wilkerson, R. B. (Department of Biochemistry and Molecular Genetics. University of Colorado Anschutz Medical Campus) ; Kahn, D. E. (Linda Crnic Institute for Down Syndrome. University of Colorado Anschutz Medical Campus) ; Joshi, M. (Functional Genomics Facility. University of Colorado Anschutz Medical Campus) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; D'Alessandro, A. (Department of Biochemistry and Molecular Genetics. University of Colorado Anschutz Medical Campus) ; Costello, J. C. (Department of Pharmacology. University of Colorado Anschutz Medical Campus) ; Sullivan, K. D. (Functional Genomics Facility. University of Colorado Anschutz Medical Campus) ; Espinosa, J. M. (Department of Molecular. Cellular and Developmental Biology. University of Colorado Boulder) ; Universitat Autònoma de Barcelona
Trisomy 21 (T21) causes Down syndrome (DS), affecting immune and neurological function by ill-defined mechanisms. Here we report a large metabolomics study of plasma and cerebrospinal fluid, showing in independent cohorts that people with DS produce elevated levels of kynurenine and quinolinic acid, two tryptophan catabolites with potent immunosuppressive and neurotoxic properties, respectively. [...]
2019 - DOI (Digital Object Identifier)

10.1038/s41467-019-12739-9
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 4766

Detailed record -

See also: similar author names
10	Smith, K.
6	Smith, K. J.
46	Smith, K. M.
1	Smith, K. P.
2	Smith, K.W.
1	Smith, Kathryn E
1	Smith, Katy
1	Smith, Kenneth G. C.

Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.