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15 p, 1.6 MB A trans-omics assessment of gene-gene interaction in early-stage NSCLC / Chen, Jiajin (Nanjing Medical University) ; Song, Yunjie (Department of Biostatistics. Nanjing Medical University) ; Li, Yi (Department of Biostatistics. University of Michigan) ; Wei, Yongyue (Nanjing Medical University) ; Shen, Sipeng (Department of Biostatistics. Nanjing Medical University) ; Zhao, Yang (Department of Biostatistics. Nanjing Medical University) ; You, Dongfang (Department of Biostatistics. Nanjing Medical University) ; Su, Li (Harvard Medical School) ; Bjaanæs, Maria Moksnes (Department of Cancer Genetics Oslo University Hospital) ; Karlsson, Anna (Department of Clinical Sciences. Lund University) ; Planck, Maria (Department of Clinical Sciences. Lund University) ; Staaf, Johan (Department of Clinical Sciences. Lund University) ; Helland, Åslaug (Institute of Clinical Medicine. University of Oslo) ; Esteller, M (Universitat de Barcelona) ; Shen, Hongbing (Nanjing Medical University) ; Christiani, David C. (Harvard Medical School) ; Zhang, Ruyang (Nanjing Medical University) ; Chen, Feng (State Key Laboratory of Reproductive Medicine. Nanjing Medical University)
Epigenome-wide gene-gene (G × G) interactions associated with non-small-cell lung cancer (NSCLC) survival may provide insights into molecular mechanisms and therapeutic targets. Hence, we proposed a three-step analytic strategy to identify significant and robust G × G interactions that are relevant to NSCLC survival. [...]
2023 - 10.1002/1878-0261.13345
Molecular Oncology, Vol. 17 Núm. 1 (january 2023) , p. 173-187  
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