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6 p, 348.3 KB Fluorescence In Situ Hybridization and Immunohistochemistry as Diagnostic Methods for ALK Positive Non-Small Cell Lung Cancer Patients / Martinez, Pablo (Vall d'Hebron Institut d'Oncologia) ; Hernandez-Losa, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cedrés, Susana (Vall d'Hebron Institut d'Oncologia) ; Castellvi, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martinez-Marti, Alex (Vall d'Hebron Institut d'Oncologia) ; Tallada, Natalia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Murtra-Garrell, Nuria (Vall d'Hebron Institut d'Oncologia) ; Navarro, Alejandro (Vall d'Hebron Institut d'Oncologia) ; Rodriguez-Freixinos, Victor (Vall d'Hebron Institut d'Oncologia) ; Canela, Mercedes (Vall d'Hebron Institut d'Oncologia) ; Ramon y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Felip, Enriqueta (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
Anaplastic Lymphoma Kinase (ALK) positivity represents a novel molecular target in a subset of Non-Small Cell Lung Cancers (NSCLC). We explore Fluorescence in situ Hybridization (FISH) and Immunohistochemistry (IHC) as diagnostic methods for ALK positive patients and to describe its prevalence and outcomes in a population of NSCLC patients. [...]
2013 - 10.1371/journal.pone.0052261
PloS one, Vol. 8 (january 2013)  

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