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10 p, 912.2 KB Pharmacokinetic analysis of omomyc shows lasting structural integrity and long terminal half-Life in tumor tissue / Beaulieu, Marie-Eve (Peptomyc SL) ; Martínez-Martín, Sandra (Peptomyc SL) ; Kaur, Jastrinjan (Vall d'Hebron Institut d'Oncologia) ; Castillo Cano, Virginia (Peptomyc SL) ; Massó Vallés, Daniel (Peptomyc SL) ; Foradada Felip, Laia (Peptomyc SL) ; López-Estévez, Sergio (Peptomyc SL) ; Serrano del Pozo, Erika (Vall d'Hebron Institut d'Oncologia) ; Thabussot, Hugo (Peptomyc SL) ; Soucek, Laura (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
MYC is an oncoprotein causally involved in the majority of human cancers and a most wanted target for cancer treatment. Omomyc is the best-characterized MYC dominant negative to date. In the last years, it has been developed into a therapeutic miniprotein for solid tumor treatment and recently reached clinical stage. [...]
2023 - 10.3390/cancers15030826
Cancers, Vol. 15, Issue 3 (February 2023) , art. 826  
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