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13 p, 2.1 MB |
Immunological Pattern in IgA Nephropathy
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Esteve Cols, Clara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Graterol Torres, Freddzia-Amanda (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Marco Rusiñol, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Navarro Díaz, Maruja Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ara del Rey, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The current gold-standard diagnostic technique for IgA nephropathy (IgAN), the leading form of primary glomerulonephritis, is renal biopsy. CD89 (the main IgA receptor) is expressed on the surface of monocytes and plays a role in disease pathogenesis. [...]
2020 -  10.3390/ijms21041389
International journal of molecular sciences, Vol. 21 (february 2020)
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15 p, 3.0 MB |
Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia
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Zielen, Stefan (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ;
Duecker, Ruth Pia (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ;
Woelke, Sandra (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ;
Donath, Helena (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ;
Bakhtiar, Shahrzad (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ;
Buecker, Aileen (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ;
Kreyenberg, Hermann (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ;
Huenecke, Sabine (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ;
Bader, Peter (Goethe University. Division for Stem Cell Transplantation, Immunology and Intensive Care Unit) ;
Mahlaoui, Nizar (Necker Children's University Hospital. Pediatric Immunology-Hematology and Rheumatology Unit) ;
Ehl, Stephan (University of Freiburg. Institute for Immunodeficiency) ;
El-Helou, Sabine M. (Hannover Medical School. Department of Rheumatology and Immunology) ;
Pietrucha, Barbara (The Children's Memorial Health Institute. Department of Immunology) ;
Plebani, Alessandro (University of Brescia. Department of Clinical and Experimental Sciences) ;
van der Flier, Michiel (Radboud University Medical Center. Section Pediatric Infectious Diseases) ;
van Aerde, Koen (Radboud University Medical Center. Department of Pediatrics) ;
Kilic, Sara S. (Uludag University. Department of Pediatric Immunology and Rheumatology) ;
Reda, Shereen M. (Ain Shams University. Department of Pediatrics) ;
Kostyuchenko, Larysa (Western Ukrainian Specialized Children's Medical Centre) ;
McDermott, Elizabeth (Nottingham University Hospitals NHS Trust (Regne Unit)) ;
Galal, Nermeen (Cairo University Specialized Pediatric Hospital. Department of Pediatrics) ;
Pignata, Claudio (Federico II University. Department of Translational Medical Sciences) ;
Santos-Pérez, Juan Luis (Hospital Universitario Virgen de las Nieves (Granada)) ;
Laws, Hans-Juergen (Heinrich-Heine University. Department of Pediatric Oncology, Hematology and Clinical Immunology) ;
Niehues, Tim (Centre for Child and Adolescent Health (Krefeld, Germany)) ;
Kutukculer, Necil (Ege University. Department of Pediatric Immunology) ;
Seidel, Markus G. (Medical University Graz. Department of Pediatrics and Adolescent Medicine) ;
Marques, Laura (Porto Hospital Center. Pediatric Department) ;
Ciznar, Peter (Comenius University in Bratislava. Pediatric Department) ;
Edgar, John David M. (The Royal Hospitals & Queen's University) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
von Bernuth, Horst (Charité - Universitätsmedizin Berlin) ;
Krueger, Renate (Charité - Universitätsmedizin Berlin) ;
Meyts, Isabelle (University Hospitals Leuven (Bèlgica)) ;
Baumann, Ulrich (Hannover Medical School. Department of Paediatric Pulmonology, Allergy and Neonatology) ;
Kanariou, Maria ("Aghia Sophia" Children's Hospital. Department of Immunology and Histocompatibility) ;
Grimbacher, Bodo (Albert-Ludwigs University) ;
Hauck, Fabian (Ludwig-Maximilians-University Munich. Department of Pediatrics) ;
Graf, Dagmar (MVZ Dr. Reising-Ackermann Und Kollegen (Leipzig, Germany)) ;
Granado, Luis Ignacio Gonzalez (Universidad Complutense de Madrid) ;
Prader, Seraina (University Children's Hospital Zurich. Division of Immunology and Children's Research Center) ;
Reisli, Ismail (Necmettin Erbakan University. Department of Pediatrics) ;
Slatter, Mary (Newcastle University. Primary Immunodeficiency Group, Paediatric Immunology and Haematopoietic Stem Cell Transplantation) ;
Rodríguez-Gallego, Carlos (University Fernando Pessoa Canarias. Department of Immunology) ;
Arkwright, Peter D. (University of Manchester. Lydia Becker Institute of Immunology and Inflammation) ;
Bethune, Claire (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Deripapa, Elena (National Medical Research Center of Pediatric Hematology, Oncology and Immunology (Moscow, Russia)) ;
Sharapova, Svetlana O. (Belarusian Research Center for Pediatric Oncology, Hematology and Immunology. Research Department) ;
Lehmberg, Kai (University Medical Center Hamburg-Eppendorf. Division for Pediatric Stem Cell Transplantation and Immunology) ;
Davies, E. Graham (Great Ormond Street Hospital for Children (Londres)) ;
Schuetz, Catharina (Technische Universität Dresden. Department of Pediatrics) ;
Kindle, Gerhard (University of Freiburg. FREEZE Biobank) ;
Schubert, Ralf (Goethe University. Division of Allergology, Pulmonology and Cystic Fibrosis) ;
Universitat Autònoma de Barcelona
Patients with ataxia-telangiectasia (A-T) sufer from progressive cerebellar ataxia, immunodefciency, respiratory failure, and cancer susceptibility. From a clinical point of view, A-T patients with IgA defciency show more symptoms and may have a poorer prognosis. [...]
2021 - 10.1007/s10875-021-01090-8
Journal of Clinical Immunology, Vol. 41 (september 2021) , p. 1878-1892
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26 p, 8.4 MB |
Human secretory IgM emerges from plasma cells clonally related to gut memory B cells and targets highly diverse commensals
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Magri, Giuliana (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Comerma, Laura (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Pybus, Marc (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Sintes, Jordi (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Llige, David (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Segura Garzón, Daniel (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Bascones, Sabrina (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Yeste, Ada (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya)) ;
Grasset, Emilie K. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Gutzeit, Cindy (ICAHN School of Medicine at Mount Sinai. Department of Medicine) ;
Uzzan, Mathieu (ICAHN School of Medicine at Mount Sinai. Department of Medicine) ;
Ramanujam, Meera (Boehringer Ingelheim Pharmaceuticals. Immunology and Respiratory Disease Research) ;
Van Zelm, Menno C. (Monash University and Alfred Hospital. Department of Immunology and Pathology) ;
Albero González, Raquel (Hospital del Mar (Barcelona, Catalunya)) ;
Vázquez, Ivonne (Hospital del Mar (Barcelona, Catalunya)) ;
Iglesias, Mar (Universitat Autònoma de Barcelona) ;
Serrano, Sergi (Universitat Autònoma de Barcelona) ;
Márquez, Lucía (Hospital del Mar (Barcelona, Catalunya)) ;
Mercadé, Elena (Universitat de Barcelona. Departament de Biologia) ;
Mehandru, Saurabh (ICAHN School of Medicine at Mount Sinai. Department of Medicine) ;
Cerutti, Andrea (Institució Catalana de Recerca i Estudis Avançats)
Secretory immunoglobulin A (SIgA) enhances host-microbiota symbiosis, whereas SIgM remains poorly understood. We found that gut IgM + plasma cells (PCs) were more abundant in humans than mice and clonally related to a large repertoire of memory IgM + B cells disseminated throughout the intestine but rare in systemic lymphoid organs. [...]
2017 - 10.1016/j.immuni.2017.06.013
Immunity, Vol. 47, issue 1 (July 2017) , p. 118-134
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