Resultats globals: 6 registres trobats en 0.04 segons.
Articles, 6 registres trobats
Articles 6 registres trobats  
1.
11 p, 1.0 MB Prevalence of vertebral fractures and their prognostic significance in the survival in patients with chronic kidney disease stages 3-5 not on dialysis / Castro-Alonso, Cristina (Universitat de València) ; D'Marco, Luis (Universitat de València) ; Pomes Tallo, Jaume (Hospital Clínic i Provincial de Barcelona) ; Conill, Montserrat Del Amo (Hospital Clínic i Provincial de Barcelona) ; García-Diez, Ana Isabel (Hospital Clínic i Provincial de Barcelona) ; Molina, Pablo (Universitat de València) ; Puchades, Mª Jesús (Universitat de València) ; Valdivielso, José Manuel (Instituto de Salud Carlos III) ; Escudero Quesada, Verónica (Universitat de València) ; Bover, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Navarro-González, Juan F. (Universidad de La Laguna) ; Ribas, Begoña (Hospital Universitario La Paz (Madrid)) ; Pallardo, Luis M. (Universitat de València) ; Gorriz, Jose Luis (Universitat de València) ; Universitat Autònoma de Barcelona
The prevalence of vertebral fractures (VF) and their association with clinical risk factors and outcomes are poorly documented in chronic kidney disease (CKD) cohorts. The aim of the study was to evaluate the prevalence of VF in patients with non-dialysis dependent CKD (NDD-CKD), their value in predicting mortality and its correlation with parameters of bone mineral metabolism and vascular calcification. [...]
2020 - 10.3390/JCM9051604
Journal of clinical medicine, Vol. 9 Núm. 5 (may 2020) , p. 1-11  
2.
11 p, 1.1 MB Clinical Approach to Vascular Calcification in Patients With Non-dialysis Dependent Chronic Kidney Disease : Mineral-Bone Disorder-Related Aspects / Bover, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Aguilar, Armando (Instituto Mexicano del Seguro Social) ; Arana Aliaga, Carolt (Institut d'Investigació Biomèdica Sant Pau) ; Molina, Pablo (Hospital Universitari Doctor Peset (València)) ; Lloret, Maria Jesus (Institut d'Investigació Biomèdica Sant Pau) ; Ochoa, Jackson (Institut d'Investigació Biomèdica Sant Pau) ; Berná, Gerson (Institut d'Investigació Biomèdica Sant Pau) ; Gutiérrez-Maza, Yessica G. (Instituto Mexicano del Seguro Social) ; Rodrigues, Natacha (Universitário Lisboa Norte) ; D'Marco, Luis (Hospital Clínic Universitari (València)) ; Górriz, José L. (Hospital Clínic Universitari (València)) ; Universitat Autònoma de Barcelona
Chronic kidney disease (CKD) is associated with a very high morbimortality, mainly from cardiovascular origin, and CKD is currently considered in the high- or very high risk- cardiovascular risk category. [...]
2021 - 10.3389/fmed.2021.642718
Frontiers in Medicine, Vol. 8 (may 2021)  
3.
21 p, 3.1 MB Emerging Roles of Lysyl Oxidases in the Cardiovascular System : New Concepts and Therapeutic Challenges / Martínez-González, José (Institut d'Investigació Biomèdica Sant Pau) ; Varona, Saray (Institut d'Investigació Biomèdica Sant Pau) ; Cañes Esteve, Laia (Institut d'Investigació Biomèdica Sant Pau) ; Galán, María (Institut d'Investigació Biomèdica Sant Pau) ; Briones, Ana M.. (Hospital Universitario La Paz (Madrid)) ; Cachofeiro, Victoria (Universidad Complutense de Madrid) ; Rodríguez, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Lysyl oxidases (LOX and LOX-likes (LOXLs) isoenzymes) belong to a family of copper-dependent enzymes classically involved in the covalent cross-linking of collagen and elastin, a pivotal process that ensures extracellular matrix (ECM) stability and provides the tensile and elastic characteristics of connective tissues. [...]
2019 - 10.3390/biom9100610
Biomolecules, Vol. 9 (october 2019)  
4.
19 p, 1.2 MB Role of the Scavenger Receptor CD36 in Accelerated Diabetic Atherosclerosis / Navas Madroñal, Miquel (Institut d'Investigació Biomèdica Sant Pau) ; Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ; Camacho, Mercedes (Institut d'Investigació Biomèdica Sant Pau) ; Consegal, Marta (Institut d'Investigació Biomèdica Sant Pau) ; Ramírez-Morros, Anna (Institut Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ; Perez, Paulina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alonso Pedrol, Núria (Institut Germans Trias i Pujol) ; Galán, María (Institut d'Investigació Biomèdica Sant Pau) ; Mauricio Puente, Dídac (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ; Universitat Autònoma de Barcelona
Diabetes mellitus entails increased atherosclerotic burden and medial arterial calcification, but the precise mechanisms are not fully elucidated. We aimed to investigate the implication of CD36 in inflammation and calcification processes orchestrated by vascular smooth muscle cells (VSMCs) under hyperglycemic and atherogenic conditions. [...]
2020 - 10.3390/ijms21197360
International journal of molecular sciences, Vol. 21 (october 2020)  
5.
5 p, 1.6 MB Effects of SNF472, a Novel Inhibitor of Hydroxyapatite Crystallization in Patients Receiving Hemodialysis - Subgroup Analyses of the CALIPSO Trial / Raggi, Paolo (Division of Cardiology and Department of Medicine, University of Alberta, Edmonton, Alberta, Canada) ; Bellasi, Antonio (Research, Innovation and Brand Reputation Unit, ASST Papa Giovanni XXIII, Bergamo, Italy) ; Sinha, Smeeta (Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, United Kingdom) ; Bover, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Rodriguez, Mariano (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ; Ketteler, Markus (Department of General Internal Medicine and Nephrology, Robert-Bosch-Krankenhaus, Stuttgart, Germany) ; Bushinsky, David A. (Department of Medicine, University of Rochester School of Medicine, Rochester, New York, USA) ; Garg, Rekha (PharmaDRS, LLC, San Diego, California, USA) ; Perelló, Joan (University of the Balearic Islands, Palma, Spain) ; Gold, Alex (Department of Medicine, Stanford University, Palo Alto, California, USA) ; Chertow, Glenn M. (Department of Medicine, Stanford University, Palo Alto, California, USA) ; Universitat Autònoma de Barcelona
Coronary artery calcium (CAC) is highly prevalent and linked with poor outcomes in patients receiving maintenance hemodialysis, and its reduction may improve patient prognosis. SNF472, a selective inhibitor of hydroxyapatite crystallization, slows CAC progression in patients receiving maintenance hemodialysis. [...]
2020 - 10.1016/j.ekir.2020.09.032
Kidney International Reports, Vol. 5 (november 2020) , p. 2178-2182  
6.
9 p, 506.6 KB Trial design and baseline characteristics of CaLIPSO : a randomized, double-blind placebo-controlled trial of SNF472 in patients receiving haemodialysis with cardiovascular calcification / Bellasi, Antonio (Research, Innovation and Brand Reputation Unit, ASST Papa Giovanni XXIII) ; Raggi, Paolo (Department of Medicine, Mazankowski Alberta Heart Institute and University of Alberta) ; Bover, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Bushinsky, David A. (Department of Medicine, University of Rochester Medical Center) ; Chertow, Glenn M. (Department of Medicine, Stanford University) ; Ketteler, Markus (Department of General Internal Medicine and Nephrology, Robert-Bosch-Krankenhaus) ; Rodriguez, Mariano (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ; Sinha, Smeeta (Department of Renal Medicine, Salford Royal NHS Foundation Trust) ; Salcedo, Carolina (Research and Development, Sanifit Therapeutics) ; Garg, Rekha (Research and Development, Sanifit Therapeutics) ; Gold, Alex (Research and Development, Sanifit Therapeutics) ; Perelló, Joan (Research and Development, Sanifit Therapeutics) ; Universitat Autònoma de Barcelona
The objective of CaLIPSO, a Phase 2b, randomized, double-blind, placebo-controlled clinical trial, is to test the hypothesis that myo-inositol hexaphosphate (SNF472) attenuates the progression of cardiovascular calcification in patients receiving maintenance haemodialysis. [...]
2019 - 10.1093/ckj/sfz144
Clinical Kidney Journal, Vol. 14 (october 2019) , p. 366-374  

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