UAB Digital Repository of Documents 4 records found  Search took 0.00 seconds. 
1.
19 p, 4.3 MB Deficits in neuronal architecture but not over-inhibition are main determinants of reduced neuronal network activity in a mouse model of overexpression of Dyrk1A / Manubens-Gil, Linus (Southeast University (SEU)) ; Pons-Espinal, Meritxell (Universitat de Barcelona. Institut de Biomedicina) ; Gener, Thomas (Institut Català de Nanociència i Nanotecnologia) ; Ballesteros-Yañez, Inmaculada (Universidad de Castilla-La Mancha) ; Martínez de Lagrán, María (Center for Genomic Regulation) ; Dierssen, Mara (Biomedical Research Networking Center for Rare Diseases (CIBERER))
In this study, we investigated the impact of Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Dyrk1A) overexpression, a gene associated with Down syndrome, on hippocampal neuronal deficits in mice. [...]
2024 - 10.1093/cercor/bhad431
Cerebral cortex (New York, N.Y.), Vol. 34, Issue 1, (January 2024) , art. bhad431  
2.
16 p, 1.8 MB Neural signatures of predictive language processing in Parkinson's disease with and without mild cognitive impairment / León-Cabrera, Patricia (Institut d'Investigació Biomèdica de Bellvitge) ; Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ; Morís, J. (Department of Educational and Evolutive Psychology. University of Granada) ; Martinez-Horta, Saul (Institut d'Investigació Biomèdica Sant Pau) ; Marín-Lahoz, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Horta, Andrea (Institut d'Investigació Biomèdica Sant Pau) ; Bejr-kasem, Helena (Institut d'Investigació Biomèdica Sant Pau) ; Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez-Fornells, A. (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona
Cognitive deficits are common in Parkinson's disease (PD), with some PD patients meeting criteria for mild cognitive impairment (MCI). An unaddressed question is whether linguistic prediction is preserved in PD. [...]
2021 - 10.1016/j.cortex.2021.03.032
Cortex, Vol. 141 (august 2021) , p. 112-127  
3.
14 p, 2.1 MB Stable Encoding of Visual Cues in the Mouse Retrosplenial Cortex / Powell, Anna (School of Psychology) ; Connelly, William M. (School of Medicine) ; Vasalauskaite, Asta (School of Biosciences) ; Nelson, Andrew J. D. (School of Psychology) ; Vann, Seralynne D. (School of Psychology) ; Aggleton, John P. (School of Psychology) ; Sengpiel, Frank (Neuroscience and Mental Health Research Institute) ; Ranson, Adam (Universitat Autònoma de Barcelona. Institut de Neurociències)
The rodent retrosplenial cortex (RSC) functions as an integrative hub for sensory and motor signals, serving roles in both navigation and memory. While RSC is reciprocally connected with the sensory cortex, the form in which sensory information is represented in the RSC and how it interacts with motor feedback is unclear and likely to be critical to computations involved in navigation such as path integration. [...]
2020 - 10.1093/cercor/bhaa030
Cerebral cortex (New York, N.Y.), Vol. 30 (march 2020) , p. 4424-4437  
4.
17 p, 2.1 MB Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells / Bosch, Carles (Universitat de Barcelona. Parc Cientific de Barcelona) ; Masachs, Nuria (Universitat de Barcelona. Parc Cientific de Barcelona) ; Exposito-Alonso, David (Universitat de Barcelona. Parc Cientific de Barcelona) ; Martínez, Albert (Universitat de Barcelona. Parc Cientific de Barcelona) ; Teixeira, Cátia M. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Fernaud, Isabel (Universidad Politécnica de Madrid. Centro de Tecnología Biomédica) ; Pujadas, Lluís (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ulloa, Fausto (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Comella i Carnicé, Joan Xavier 1963- (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; DeFelipe, Javier (Universidad Politécnica de Madrid. Centro de Tecnología Biomédica) ; Merchán-Pérez, Angel (Universidad Politécnica de Madrid. Departamento de Arquitectura y Tecnología de Sistemas Informáticos) ; Soriano García, Eduardo (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The extracellular protein Reelin has an important role in neurological diseases, including epilepsy, Alzheimer's disease and psychiatric diseases, targeting hippocampal circuits. Here we address the role of Reelin in the development of synaptic contacts in adult-generated granule cells (GCs), a neuronal population that is crucial for learning and memory and implicated in neurological and psychiatric diseases. [...]
2016 - 10.1093/cercor/bhw216
Cerebral cortex (New York, N.Y.), Vol. 26, Issue 11 (October 2016) , p. 4282-4298  

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