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9 p, 1.3 MB Altered cross-talk between the hypothalamus and non-homeostatic regions linked to obesity and difficulty to lose weight / Contreras Rodríguez, Oren (Institut d'Investigació Biomèdica de Bellvitge) ; Vilar-López, Raquel (Universidad de Granada. Mind, Brain and Behavior Research Center) ; Andrews, Zane B. (Monash Biomedicine Discovery Institute. Metabolic Disease and Obesity Program) ; Navas, Juan F.. (University of Granada. Department of Experimental Psychology) ; Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ; Verdejo-García, Antonio (Monash University. School of Psychological Sciences and Monash Institute of Cognitive and Clinical Neurosciences)
Interactions between the hypothalamus and non-homeostatic regions may contribute to explain the difficulty to lose weight in obesity, an assumption never tested in human longitudinal studies. We investigated whether the functional connectivity between the medial and lateral hypothalamus (MH and LH) and corticostriatal regions differs between individuals with excess weight (n = 42) and normal weight (n = 39) using a seed-based resting-state approach. [...]
2017 - 10.1038/s41598-017-09874-y
Scientific reports, Vol. 7 (august 2017)  

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