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12 p, 4.3 MB Beyond molecular tumor heterogeneity : protein synthesis takes control / Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castellvi, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hümmer, Stefan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Peg, Vicente (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pelletier, Jerry (Montreal, QC Canada) ; Sonenberg, Nahum (Montreal, QC Canada) ; Universitat Autònoma de Barcelona
One of the daunting challenges facing modern medicine lies in the understanding and treatment of tumor heterogeneity. Most tumors show intra-tumor heterogeneity at both genomic and proteomic levels, with marked impacts on the responses of therapeutic targets. [...]
2018 - 10.1038/s41388-018-0152-0
Oncogene, Vol. 37 (february 2018) , p. 2490-2501  

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