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1.
16 p, 1.2 MB Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers / Chereau, Fanny (Université Paris-Saclay) ; Madec, Yoann (Institut Pasteur) ; Sabin, Caroline A (Research Department of Infection and Population Health (Regne Unit)) ; Obel, Niels (Copenhagen University Hospital Rigshospitalet) ; Ruiz-Mateos, Ezequiel (Instituto de Biomedicina de Sevilla) ; Chrysos, Georgios (Tzaneio General Hospital of Piraeus) ; Fidler, Sarah (Imperial College (Regne Unit)) ; Lehmann, Clara (University of Cologne and German Center for Infection Research) ; Zangerle, Robert (DMedical University Innsbruck) ; Wittkop, Linda (University Bordeaux) ; Reiss, Peter (Stichting HIV Monitoring) ; Hamouda, Osamah (Robert Koch Institute) ; Estrada Perez, Vicente (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Leal, Manuel (Instituto de Biomedicina de Sevilla) ; Mocroft, Amanda (Research Department of Infection and Population Health (Regne Unit)) ; García de Olalla, Patricia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Ammassari, Adriana (Istituto Nazionale Malattie Infettive) ; D'Arminio Monforte, Antonella (University Hospital (Itàlia)) ; Mussini, Cristina (University of Modena and Reggio Emilia) ; Segura, Ferran (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Castagna, Antonella (San Raffaele Vita Salute University) ; Cavassini, Matthias (Lausanne University Hospital) ; Grabar, Sophie (Institut Pierre Louis d'Epidémiologie et de Santé Publique) ; Morlat, Philippe (Université de Bordeaux) ; De Wit, Stéphane (Université Libre de Bruxelles) ; Lambotte, Olivier (Université Paris Sud) ; Meyer, Laurence (Université Paris-Saclay) ; Universitat Autònoma de Barcelona
HIV controllers (HICs) spontaneously maintain HIV viral replication at low level without antiretroviral therapy (ART), a small number of whom will eventually lose this ability to control HIV viremia. [...]
2017 - 10.1371/journal.pone.0173893  
Registre complet - Creative Commons
2.
7 p, 259.3 KB Mortality According to CD4 Count at Start of Combination Antiretroviral Therapy Among HIV-infected Patients Followed for up to 15 Years After Start of Treatment : Collaborative Cohort Study / May, Margaret T. ; Vehreschild, Jorg-Janne ; Trickey, Adam ; Obel, Niels ; Reiss, Peter ; Bonnet, Fabrice ; Mary-Krause, Murielle ; Samji, Hasina ; Cavassini, Matthias ; Gill, Michael John ; Shepherd, Leah C. ; Crane, Heidi ; D'Arminio Monforte, Antonella ; Burkholder, Greer A. ; Johnson, Margaret M. ; Sobrino-Vegas, Paz ; Domingo, Pere (Domingo Pedrol) ; Zangerle, Robert (Universitat Autònoma de Barcelona. Departament de Medicina) ; Justice, Amy C. ; Sterling, Timothy R. ; Miró, José M. ; Sterne, Jonathan A. C.
The strong association of CD4 count at start of combination therapy with subsequent survival in HIV-infected patients diminished during the first 5 years of treatment. After 5 years, lower baseline CD4 counts were not associated with higher mortality. [...]
2016 - 10.1093/cid/ciw183
Clinical Infectious Diseases, Vol. 62 (march 2016) , p. 1571-1577  
Registre complet - Creative Commons

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