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14 p, 2.9 MB Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods / Xu, Zhen (Huazhong Agricultural University. Department of Aquatic Animal Medicine) ; Takizawa, Fumio (University of Pennsylvania. Department of Pathobiology) ; Parra, David (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Gómez, Daniela (University of Pennsylvania. Department of Pathobiology) ; von Gersdorff Jørgensen, Louise (University of Copenhagen. Department of Veterinary Disease Biology) ; LaPatra, Scott E. (Clear Springs Foods Inc) ; Sunyer, J. Oriol (University of Pennsylvania. Department of Pathobiology)
Gas-exchange structures are critical for acquiring oxygen, but they also represent portals for pathogen entry. Local mucosal immunoglobulin responses against pathogens in specialized respiratory organs have only been described in tetrapods. [...]
2016 - 10.1038/ncomms10728
Nature communications, Vol. 7 (February 2016) , art. 10728  

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