Resultats globals: 2 registres trobats en 0.02 segons.
Articles, 2 registres trobats
Articles 2 registres trobats  
1.
10 p, 790.0 KB Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial : A Secondary Analysis / Farrant, Mary (University of California) ; Easton, J.Donald (University of California) ; Adelman, Eric E. (University of Wisconsin) ; Cucchiara, Brett L. (University of Pennsylvania) ; Barsan, Willian G. (University of Michigan) ; Tillman, Holly J. (Medical University of South Carolina) ; Elm, Jordan J. (Medical University of South Carolina) ; Kim, Anthony S. (University of California) ; Lindblad, Anne S. (Emmes Corporation) ; Palesch, Yuyo Y. (Medical University of South Carolina) ; Zhao, Wenle (Medical University of South Carolina) ; Pauls, Keith (Medical University of South Carolina) ; Walsh, Kyle B. (University of Cincinnati) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Bernstein, Richard A. (Northwestern University) ; Johnston, Claiborne (University of Texas at Austin) ; Universitat Autònoma de Barcelona
Debate continues about the value of event adjudication in clinical trials and whether independent centralized assessments improve reliability and validity of study results in masked randomized trials compared with local, investigator-assessed end points. [...]
2019 - 10.1001/jamanetworkopen.2019.10769
JAMA network open, Vol. 2 Núm. 9 (june 2019) , p. e1910769  
2.
8 p, 351.8 KB Efficacy and Safety of Ticagrelor and Aspirin in Patients with Moderate Ischemic Stroke : An Exploratory Analysis of the THALES Randomized Clinical Trial / Wang, Yongjun (China National Clinical Research Center for Neurological Diseases) ; Pan, Yuesong (China National Clinical Research Center for Neurological Diseases) ; Li, Hao (China National Clinical Research Center for Neurological Diseases) ; Amarenco, Pierre (University of Paris) ; Denison, Hans (AstraZeneca) ; Evans, Scott R. (George Washington University) ; Himmelmann, Anders (AstraZeneca) ; James, Stefan (Uppsala University) ; Birve, Filip (AstraZeneca) ; Ladenvall, Per (AstraZeneca) ; Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ; Johnston, S. Claiborne (University of Texas at Austin) ; Universitat Autònoma de Barcelona
Importance: Prior trials of dual antiplatelet therapy excluded patients with moderate ischemic stroke. These patients were included in the Acute Stroke or Transient Ischaemic Attack Treated With Ticagrelor and ASA for Prevention of Stroke and Death (THALES) trial, but results have not been reported separately, raising concerns about safety and efficacy in this subgroup. [...]
2021 - 10.1001/jamaneurol.2021.2440
JAMA Neurology, Vol. 78 Núm. 9 (september 2021) , p. 1091-1098  

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