|
1.
|
|
10 p, 2.6 MB |
Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies
/
García-Prieto, Carlos A (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Villanueva, Lorea (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno-Costa, Alberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
González-Navarro, Europa Azucena (Department of Immunology. Hospital Clinic) ;
Juan, Manuel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Urbano-Ispizua, Álvaro (Department of Hematology. University of Barcelona) ;
Delgado, Julia (Centro de Investigación Biomedica en Red de Cancer) ;
Ortiz-Maldonado, Valetín (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Del Bufalo, Francesca (Department of Paediatric Haematology and Oncology. Bambino Gesù Children's Hospital) ;
Locatelli, Franco (Sapienza University of Rome) ;
Quintarelli, Concetta (Department of Clinical Medicine and Surgery. University of Naples Federico II) ;
Sinibaldi, Matilde (Department of Paediatric Haematology and Oncology. Bambino Gesù Children's Hospital) ;
Soler, Marta (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Castro De Moura, Manuel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ferrer, Gerardo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Urdinguio, Rocío G. (Universidad de Oviedo) ;
Fernandez, A.F. (Universidad de Oviedo) ;
Fraga, Mario F. (Universidad de Oviedo) ;
Bar, Diana (The Edmond and Lily Safra Children's Hospital) ;
Meir, Agustín (The Edmond and Lily Safra Children's Hospital) ;
Itzhaki, Orit (Ella Lemelbaum Institute for Immuno Oncology) ;
Besser, MichalJ. (Tel Aviv University) ;
Avigdor, Abraham (Sheba Medical Center) ;
Jacoby, Elad (Tel Aviv University) ;
Esteller, Manel (Universitat de Barcelona. Departament de Ciències Fisiològiques)
Background: Chimeric antigen receptor (CAR) T cells directed against CD19 (CART19) are effective in B-cell malignancies, but little is known about the molecular factors predicting clinical outcome of CART19 therapy. [...]
2022 -  10.1093/jnci/djab194
Journal of the National Cancer Institute, Vol. 114 Núm. 3 (january 2022) , p. 436-445
|
|
|
2.
|
|
4 p, 1.4 MB |
Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages
/
Bueno-Costa, Alberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Piñeyro, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Prieto, Carlos A. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ortiz-Barahona, Vanessa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martinez-Verbo, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Webster, Natalie A. (STORM Therapeutics Ltd, UK) ;
Andrews, Byron (STORM Therapeutics Ltd, UK) ;
Kol, Nitzan (Tel Aviv University, Israel) ;
Avrahami, Chen (Tel Aviv University, Israel) ;
Moshitch-Moshkovitz, Sharon (Tel Aviv University, Israel) ;
Rechavi, Gideon (Tel Aviv University, Israel) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
2022 - 10.1038/s41375-022-01621-1
Leukemia, Vol. 36 Núm. 8 (august 2022) , p. 2121-2124
|
|
|
3.
|
|
9 p, 1.5 MB |
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome
/
García-Prieto, Carlos A (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Álvarez-Errico, Damiana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Musulén, Eva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno-Costa, Alberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Vazquez Prat, Berta Nieves (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Vaquero, Alejandro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Mouse has been extensively used as a model organism in many studies to characterize biological pathways and drug effects and to mimic human diseases. Similar DNA sequences between both species facilitate these types of experiments. [...]
2022 - 10.1080/15592294.2022.2053816
Epigenetics, Vol. 17 Núm. 12 (december 2022) , p. 1677-1685
|
|
|
4.
|
|
|
5.
|
|
15 p, 1.4 MB |
Gene amplification-associated overexpression of the selenoprotein trna enzyme trit1 confers sensitivity to arsenic trioxide in small-cell lung cancer
/
Coll-Sanmartin, Laia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Piñeyro, David (Centro de Investigación Biomédica en Red de Cáncer) ;
Rosselló-Tortella, Margalida (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno-Costa, Alberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Setien, Fernando (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Villanueva, Alberto (Grup de Quimioresistències i Factors Predictius, Subprograma Contra la Resistència Terapèutica del Càncer (ProCURE)) ;
Granada, Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ruiz-Xiviller, Neus (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Kotter, Annika (Johannes Gutenberg-Universität Mainz) ;
Helm, Mark (Johannes Gutenberg-Universität Mainz) ;
Yokota, Jun (National Cancer Center Research Institute (Japò)) ;
Kawabata-Iwakawa, Reika (Gunma University Initiative for Advanced Research) ;
Kohno, Takashi (National Cancer Center (Japò)) ;
Esteller, M. (Universitat de Barcelona. Departament de Ciències Fisiològiques)
2021 - 10.3390/cancers13081869
Cancers, Vol. 13 Núm. 8 (february 2021) , p. 1869
|
|
|
6.
|
|
|
7.
|
|
11 p, 9.5 MB |
Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing
/
Pontel, Lucas B. (Instituto de Investigación en Biomedicina de Buenos Aires) ;
Bueno-Costa, Alberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Morellato, Agustín E. (Instituto de Investigación en Biomedicina de Buenos Aires) ;
Santos, Juliana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Roué, Gaël (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Universitat Autònoma de Barcelona
Ferroptosis is a form of cell death triggered by phospholipid hydroperoxides (PLOOH) generated from the iron-dependent oxidation of polyunsaturated fatty acids (PUFAs). To prevent ferroptosis, cells rely on the antioxidant glutathione (GSH), which serves as cofactor of the glutathione peroxidase 4 (GPX4) for the neutralization of PLOOHs. [...]
2022 - 10.1016/j.redox.2022.102408
Redox biology, Vol. 55 (september 2022) , p. 102408
|
|
|
8.
|
|
|
9.
|
|
13 p, 1.5 MB |
Medical vulnerability of individuals with Down syndrome to severe COVID-19-data from the Trisomy 21 Research Society and the UK ISARIC4C survey
/
Hüls, Anke (Department of Epidemiology and Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA) ;
Costa, Alberto C. S. (Departments of Pediatrics and of Psychiatry, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA) ;
Dierssen, Mara (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Baksh, R. Asaad (The London Down Syndrome (LonDownS) Consortium, London, United Kingdom) ;
Bargagna, Stefania (Fondazione Stella Maris IRCCS, Pisa, Italy) ;
Baumer, Nicole (Harvard Medical School) ;
Brandão, Ana Claudia (Hospital Israelita Albert Einstein (Sao Paolo, Brasil)) ;
Carfi, Angelo (Policlinico Universitario Agostino Gemelli IRCCS (Roma, Itàlia)) ;
Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ;
Chicoine, Brian (Advocate Medical Group Adult Down Syndrome Center, Park Ridge, IL, USA) ;
Ghosh, Sujay (Cytogenetics and Genomics Reserach Unit. Department of Zoology, University of Calcutta.Kolkata. West Bengal, India) ;
Lakhanpaul, Monica (Whttington NHS Trust, London, United Kingdom; Down Syndrome Medical Interest Group, London, United Kingdom) ;
Manso, Coral (CM: DOWN ESPAÑA, Madrid, Spain) ;
Mayer, Miguel-Angel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ortega, Maria del Carmen (Hospital Universitario 12 de Octubre (Madrid)) ;
de Asua, Diego Real (Instituto de Investigación Hospital Universitario de la Princesa) ;
Rebillat, Anne-Sophie (Institut Jérôme Lejeune, Paris, France) ;
Russell, Lauren Ashley (Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA) ;
Sgandurra, Giuseppina (Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy) ;
Valentini, Diletta (Bambino Gesù Children's Hospital) ;
Sherman, Stephanie L. (Department of Human Genetics, School of Medicine, Emory University, Atlanta, Georgia, USA) ;
Strydom, Andre (South London and the Maudsley NHS Foundation Trust) ;
Universitat Autònoma de Barcelona
Health conditions, immune dysfunction, and premature aging associated with trisomy 21 (Down syndrome, DS) may impact the clinical course of COVID-19. The T21RS COVID-19 Initiative launched an international survey for clinicians or caregivers on patients with COVID-19 and DS. [...]
2021 - 10.1016/j.eclinm.2021.100769
EClinicalMedicine, february 2021
|
|
|
10.
|
|
guest ::
email alert
or subscribe to the 
RSS feed.
