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17 p, 3.0 MB The nonlinear relationship between cerebrospinal fluid Aβ and tau in preclinical Alzheimer's disease / de Leon, Mony J.. (NYU Medical Center, New York, United States of America) ; Pirraglia, Elizabeth (NYU Medical Center, New York, United States of America) ; Osorio, Ricardo S. (Nathan Kline Institute for Psychiatric Research) ; Glodzik, Lidia (NYU Medical Center, New York, United States of America) ; Saint-Louis, Les (Lennox Hill Radiology, New York, United States of America) ; Kim, Hee-Jin (Hanyang University, Seoul, Korea) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Fossati, Silvia (NYU Medical Center, New York, United States of America) ; Laska, Eugene (NYU Medical Center, New York, United States of America) ; Siegel, Carole (NYU Medical Center, New York, United States of America) ; Butler, Tracy (NYU Medical Center, New York, United States of America) ; Li, Yi (NYU Medical Center, New York, United States of America) ; Rusinek, Henry (NYU Medical Center, New York, United States of America) ; Zetterberg, Henrik (UK Dementia Research Institute, London, United Kingdom) ; Blennow, Kaj (Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden) ; Universitat Autònoma de Barcelona
Cerebrospinal fluid (CSF) studies consistently show that CSF levels of amyloid-beta 1-42 (Aβ) are reduced and tau levels increased prior to the onset of cognitive decline related to Alzheimer's disease (AD). [...]
2018 - 10.1371/journal.pone.0191240
PloS one, Vol. 13 (february 2018)  

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