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9 p, 1005.0 KB |
Chronic hypogammaglobulinemia after allogeneic stem cell transplantation and their treatment with subcutanaeos inmunoglobulin in pediatric patients Hipogammaglobulinemia crónica postrasplante de precursores hematopoyéticos y su tratamiento con gammaglobulina subcutánea en pacientes pediátricos
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Serra Font, Sara (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
López-Granados, Lucía (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sisinni, Luisa (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Serna Berna, José (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Martinez-Martinez, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Fernández de Gamarra Martínez, Edurne (Institut d'Investigació Biomèdica Sant Pau) ;
de la Calle-Martín, Oscar (Institut d'Investigació Biomèdica Sant Pau) ;
Badell Serra, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Hypogammaglobulinemia in the first months after allogeneic hematopoietic stem cell transplantation (HSCT) is common in pediatric patients. During this phase, replacement therapy with human immunoglobulin must be administered parenterally to prevent infections. [...]
2022 -  10.1016/j.anpedi.2021.08.011
Anales de pediatría, Vol. 97 Núm. 2 (agosto 2022) , p. 103-111
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2.
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14 p, 1.7 MB |
Prognostic utility of serum free light chain ratios and heavy-light chain ratios in multiple myeloma in three PETHEMA/GEM phase III clinical trials
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López-Anglada, Lucía (Hospital 12 de Octubre (Madrid)) ;
Cueto-Felgueroso, Cecilia (Hospital 12 de Octubre (Madrid)) ;
Rosiñol, Laura (Hospital Clínic i Provincial de Barcelona) ;
Oriol, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teruel, Ana Isabel (Hospital Clínic Universitari (València)) ;
Lopez de la Guia, Ana (Hospital Universitario La Paz (Madrid)) ;
Bengoechea, Enrique (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Palomera, Luis (Hospital Clínico Universitario Lozano Blesa) ;
De Arriba, Felipe (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Hernandez, Jose Mariano (Hospital General de Segovia) ;
Granell, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Peñalver, Francisco Javier (Hospital Universitario Fundacion Alcorcon) ;
García-Sanz, Ramón (Hospital Universitario de Salamanca-IBSAL) ;
Besalduch, Juan (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Gonzalez Montes, Yolanda (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martinez, Rafael Benigno (Hospital Universitario Clínico San Carlos (Madrid)) ;
Hernández, Miguel Teodoro (Hospital Universitario de Canarias (La Laguna)) ;
Gutierrez, Norma C. (Hospital Clínic i Provincial de Barcelona) ;
Puerta, Paloma (Hospital 12 de Octubre (Madrid)) ;
Valeri, Antonio (Hospital 12 de Octubre (Madrid)) ;
Paiva, Bruno (Clínica Universidad de Navarra) ;
Bladé Creixenti, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mateos, Maria-Victoria (Hospital Clínic i Provincial de Barcelona) ;
San-Miguel, J (Clínica Universidad de Navarra) ;
Lahuerta, J. J. (Hospital Universitario 12 de Octubre (Madrid)) ;
Martínez-López, Joaquín (Hospital Universitario 12 de Octubre (Madrid)) ;
Universitat Autònoma de Barcelona
We investigated the prognostic impact and clinical utility of serum free light chains (sFLC) and serum heavy-light chains (sHLC) in patients with multiple myeloma treated according to the GEM2005MENOS65, GEM2005MAS65, and GEM2010MAS65 PETHEMA/GEM phase III clinical trials. [...]
2018 - 10.1371/journal.pone.0203392
PloS one, Vol. 13 Núm. 9 (september 2018) , p. e0203392
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3.
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8 p, 1012.2 KB |
Reduced intensity conditioning increases risk of severe cGVHD : identification of risk factors for cGVHD in a multicenter setting
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Afram, Gabriel (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Simón, Jose Antonio Pérez (Instituto de Biomedicina de Sevilla) ;
Remberger, Mats (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Caballero Velazquez, Teresa (Instituto de Biomedicina de Sevilla) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Piñana, Jose Luis (Hospital Clinico Universitario) ;
Ringden, Olle (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Lopez-Corral, Lucia (Hospital Universitario de Salamanca-IBSAL) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
López-Godino, Oriana (Hospital Universitario de Salamanca-IBSAL) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Caballero, Dolores (Hospital Universitario de Salamanca-IBSAL) ;
Ljungman, Per (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Vazquez, Lourdes (Hospital Clínico Universitario (Salamanca)) ;
Hägglund, Hans (Uppsala University Hospital) ;
Universitat Autònoma de Barcelona
Chronic graft-versus-host disease (cGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Aim is to identify risk factors for the development of cGVHD in a multicenter setting. [...]
2018 - 10.1007/s12032-018-1127-2
Medical Oncology, Vol. 35 Núm. 6 (january 2018) , p. 79
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25 p, 635.6 KB |
CD34 + Cell Selection versus Reduced-Intensity Conditioning and Unmodified Grafts for Allogeneic Hematopoietic Cell Transplantation in Patients Age >50 Years with Acute Myelogenous Leukemia and Myelodysplastic Syndrome
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Barba, Pere (Hospital Universitari Vall d'Hebron) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Zhou, Qin (Memorial Sloan Kettering Cancer Center) ;
Cho, Christina (Weill Cornell Medical College) ;
Castro-Malaspina, Hugo (Weill Cornell Medical College) ;
Devlin, Sean M (Memorial Sloan Kettering Cancer Center) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Giralt, Sergio (Weill Cornell Medical College) ;
Jakubowski, Ann A. (Weill Cornell Medical College) ;
Caballero, Dolores (Hospital Universitario Salamanca (CAUSA/IBSAL)) ;
Maloy, Molly (Memorial Sloan Kettering Cancer Center) ;
Papadopoulos, Esperanza B. (Weill Cornell Medical College) ;
Piñana, José Luis (Hospital Clínic Universitari (València)) ;
Fox, Maria Laura (Hospital Universitari Vall d'Hebron) ;
Márquez-Malaver, Francisco J. (Hospital Virgen del Rocío Sevilla) ;
Valcárcel, David (Hospital Universitari Vall d'Hebron) ;
Solano, Carlos (Hospital Clínic Universitari (València)) ;
López-Corral, Lucía (Hospital Universitario Salamanca (CAUSA/IBSAL)) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Perales, Miguel-Angel (Weill Cornell Medical College) ;
Universitat Autònoma de Barcelona
Reduced-intensity conditioning (RIC) and T cell depletion (TCD) through CD34 cell selection without the use of post-transplantation immunosuppression are 2 strategies used to reduce nonrelapse mortality (NRM) in older patients after allogeneic hematopoietic cell transplantation (allo-HCT). [...]
2018 - 10.1016/j.bbmt.2017.12.804
Biology of blood and marrow transplantation, Vol. 24 Núm. 5 (may 2018) , p. 964-972
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8 p, 692.3 KB |
Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma : Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment
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Reinoso-Segura, Marta (Universidad de Sevilla) ;
Caballero Velazquez, Teresa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Herrera, Pilar (Hospital Universitario Ramón y Cajal (Madrid)) ;
Patriarca, Francesca (University Hospital and DAME) ;
Fanin, Renato (University Hospital and DAME) ;
Bruno, Benedetto (AOU Città della Salute e della Scienza) ;
Einsele, Hermann (Medizinische Klinik and Poliklinik II University Hospital) ;
Nahi, Hareth (Karolinska University Hospital) ;
Granell, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
López-Corral, Lucía (Centro de Investigación del Cáncer-IBMCC) ;
Reguera, Juan L. (Universidad de Sevilla) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Gahrton, Gösta (European Society for Blood and Marrow Transplantation) ;
Pérez-Simón, José A. (Universidad de Sevilla) ;
Universitat Autònoma de Barcelona
The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after allogeneic stem cell transplantation (alloSCT). In contrast, disease relapse remains the most frequent cause of treatment failure and death. [...]
2022 - 10.1016/j.jtct.2022.01.026
Transplantation and Cellular Therapy, Vol. 28 Núm. 5 (may 2022) , p. 258.e1-258.e8
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11 p, 893.9 KB |
SARS-CoV-2 vaccine response and rate of breakthrough infection in patients with hematological disorders
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Piñana, José Luis (Fundación INCLIVA. Instituto de Investigación Sanitaria Hospital Clínico Universitario de Valencia) ;
López-Corral, Lucía (Hospital Clínico Universitario (Salamanca)) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Vazquez, Lourdes (Hospital Clínico Universitario (Salamanca)) ;
Pérez, Ariadna (Fundación INCLIVA. Instituto de Investigación Sanitaria Hospital Clínico Universitario de Valencia) ;
Martin-Martin, Gabriel Andres (Hospital Clínico Universitario (Salamanca)) ;
Gago, Beatriz (Hospital Regional Universitario Carlos Haya (Málaga)) ;
Sanz-Linares, Gabriela (Institut Català Oncologia-Hospital Duran i Reynals. Institut d'Investigació Biomèdica de Bellvitge) ;
Sánchez Salinas, Andrés (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Villalon, Lucia B. (Hospital Universitario Fundación Alcorcón) ;
Conesa-García, Venancio (Hospital General Universitario de Elche) ;
Olave, María Teresa (Hospital Clínico Universitario Lozano Blesa. Instituto de Investigacón Sanitaria Aragón) ;
Corona de Lapuerta, Magdalena (Hospital Universitario Ramón y Cajal (Madrid)) ;
Marcos-Corrales, Sara (Hospital Clínico Universitario (Salamanca)) ;
Tormo, Mar (Instituto de Investigación Sanitaria Fundación Para la Investigación del Hospital Clínico de Valencia) ;
Hernandez-Rivas, JA (Hospital Universitario Infanta Leonor) ;
Montoro, Juan B. (Hospital Universitari y politècnic La Fe (València)) ;
Rodríguez-Fernández, Alicia (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Risco-Gálvez, Irene (Hospital Arnau de Vilanova (València)) ;
Rodríguez-Belenguer, Pablo (Research Program on Biomedical Informatics (GRIB). Institut Hospital del Mar d'Investigacions Mèdiques. Universitat Pompeu Fabra) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínic Universitari (València)) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Ruíz-García, Montserrat M. (Hospital General Universitario de Elche) ;
Muñoz-Bellido, Juan Luis (Hospital Clínico Universitario (Salamanca)) ;
Solano, Carlos (Hospital Clínic Universitari (València)) ;
Cedillo Cedillo, Angel (Hematopoietic Stem Cell Transplantation and Cell Therapy Group) ;
Sureda, Anna (Institut Català Oncologia-Hospital Duran i Reynals. Institut d'Investigació Biomèdica de Bellvitge) ;
Navarro, David (Hospital Clínic Universitari (València))
Background: The clinical efficacy of SARS-CoV-2 vaccines according to antibody response in immunosuppressed patients such as hematological patients has not yet been established. Patients and methods: A prospective multicenter registry-based cohort study conducted from December 2020 to December 2021 by the Spanish transplant and cell therapy group was used to analyze the relationship of antibody response at 3-6 weeks after full vaccination (2 doses) with breakthrough SARS-CoV-2 infection in 1394 patients with hematological disorders. [...]
2022 - 10.1186/s13045-022-01275-7
Journal of hematology & oncology, Vol. 15 Núm. 1 (december 2022) , p. 54
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8 p, 930.0 KB |
Ruxolitinib in refractory acute and chronic graft-versus-host disease : a multicenter survey study
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Escamilla Gómez, Virginia (Universidad de Sevilla) ;
García-Gutiérrez, Valentín (University Hospital Ramon y Cajal) ;
López Corral, Lucía (Complejo Asistencial Universitario de Salamanca-IBSAL) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Pérez Martínez, Ariadna (Hospital Clínic Universitari (València)) ;
Márquez Malaver, Francisco J. (Universidad de Sevilla) ;
Caballero-Velázquez, Teresa (Universidad de Sevilla) ;
González Sierra, Pedro A. (Hospital Universitario (Granada)) ;
Viguria Alegría, María C. (Complejo Hospitalario de Navarra) ;
Parra Salinas, Ingrid M. (Hospital Universitario Miguel Servet (Saragossa)) ;
Calderón Cabrera, Cristina (Universidad de Sevilla) ;
González Vicent, Marta (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Rodríguez Torres, Nancy (Universidad de Sevilla) ;
Parody Porras, Rocío (Instituto Catalá de Oncología Hospitalet) ;
Ferra Coll Christelle (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Orti, Guillermo (Hospital Universitari Vall d'Hebron) ;
Valcárcel Ferreiras, David (Hospital Universitari Vall d'Hebron) ;
de la Cámara Llanzá, Rafael (Hospital Universitario de la Princesa (Madrid)) ;
Molés, Paula (Hospital Universitari i Politècnic La Fe (València)) ;
Velázquez-Kennedy, Kyra (Hospital Universitari Ramon y Cajal) ;
João Mende, María (Complejo Asistencial Universitario de Salamanca-IBSAL) ;
Caballero Barrigón, Dolores (Complejo Asistencial Universitario de Salamanca-IBSAL) ;
Pérez, Estefanía (Complejo Asistencial Universitario de Salamanca-IBSAL) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Saavedra Gerosa, Silvanna (Institut d'Investigació Biomèdica Sant Pau) ;
Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Poch, Marc (Clinic Hospital Universitari de Valencia) ;
Zudaire Ripa, María T. (Complejo Hospitalario de Navarra) ;
Díaz Pérez, Miguel A. (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Molina Angulo, Blanca (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Sánchez Ortega, Isabel (Instituto Catalá de Oncología Hospitalet) ;
Sanz Caballer, Jaime (Hospital Universitari i Politècnic La Fe (València)) ;
Montoro Gómez, Juan (Hospital Universitari i Politècnic La Fe (València)) ;
Espigado Tocino, Ildefonso (Universidad de Sevilla) ;
Pérez-Simón, José A. (Universidad de Sevilla) ;
Universitat Autònoma de Barcelona
Graft-versus-host disease is the main cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. First-line treatment is based on the use of high doses of corticosteroids. [...]
2020 - 10.1038/s41409-019-0731-x
Bone marrow transplantation, Vol. 55 Núm. 3 (january 2020) , p. 641-648
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15 p, 3.0 MB |
Identifying Early Infections in the Setting of CRS With Routine and Exploratory Serum Proteomics and the HT10 Score Following CD19 CAR-T for Relapsed/Refractory B-NHL
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Rejeski, Kai (Bavarian Cancer Research Center (Alemanya)) ;
Blumenberg, Viktoria (Bavarian Cancer Research Center (Alemanya)) ;
Iacoboni, Gloria (Vall d'Hebron Institut d'Oncologia) ;
López Corral, Lucia (Centro de Investigación del Cáncer-IBMCC (Espanya)) ;
Kharboutli, Soraya (University Hospital Erlangen (Alemanya)) ;
Hernani, Rafael (Hospital Clínico Universitario (Espanya)) ;
Petrera, Agnese (German Research Center for Environmental Health (Alemanya)) ;
Müller, Niklas (University Hospital (Alemanya)) ;
Hildebrand, Friederike (University Hospital (Alemanya)) ;
Frölich, Lisa (German Cancer Consortium (Alemanya)) ;
Karschnia, Philipp (University Hospital (Alemanya)) ;
Schmidt, Christian (University Hospital (Alemanya)) ;
Cordas dos Santos, David M. (German Cancer Consortium (Alemanya)) ;
Piñana, José Luis (Hospital Clínic Universitari (València)) ;
Müller, Fabian (University Hospital Erlangen (Alemanya)) ;
Martin, Ana Africa (Centro de Investigación del Cáncer-IBMCC (Espanya)) ;
Dreyling, Martin (University Hospital (Alemanya)) ;
von Bergwelt-Baildon, Michael (Bavarian Cancer Research Center (Alemanya)) ;
Barba, Pere (Vall d'Hebron Institut d'Oncologia) ;
Subklewe, Marion (Bavarian Cancer Research Center (Alemanya)) ;
Bücklein, Veit (Bavarian Cancer Research Center (Alemanya)) ;
Universitat Autònoma de Barcelona
Early fever after chimeric antigen receptor T-cell (CAR-T) therapy can reflect both an infection or cytokine release syndrome (CRS). Identifying early infections in the setting of CRS and neutropenia represents an unresolved clinical challenge. [...]
2023 - 10.1097/HS9.0000000000000858
HemaSphere, Vol. 7 (april 2023)
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13 p, 3.3 MB |
Results of haploidentical transplant in patients with donor-specific antibodies : a survey on behalf of the Spanish Group of Hematopoietic Transplant and Cell Therapy
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Bailén, Rebeca (Hospital General Universitario Gregorio Marañón) ;
Alenda, Raquel (Centro de Transfusión de la Comunidad de Madrid) ;
Herruzo-Delgado, Beatriz (Hospital Regional Universitario de Málaga) ;
Acosta-Fleitas, Cynthia (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Vallés, Ana (Hospital Universitario Ramón y Cajal (Madrid)) ;
Esquirol, Albert (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Fonseca, Marta (Hospital Clínico Universitario (Salamanca)) ;
Solán, Laura (Hospital Universitario Fundación Jiménez Díaz) ;
Sánchez-Vadillo, Irene (Hospital Universitario La Paz (Madrid)) ;
Bautista, Guiomar (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Bento, Leyre (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
López-Godino, Oriana (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Pérez-Martínez, Ariadna (Hospital Clínic Universitari (València)) ;
Torrent Catarineu, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Zanabili, Joud (Hospital Universitario Central de Asturias) ;
Calbacho, Maria (Hospital Universitario 12 de Octubre (Madrid)) ;
Moreno, Miguel Ángel (Centro de Transfusión de la Comunidad de Madrid) ;
Pascual-Cascón, María Jesús (Hospital Regional Universitario de Málaga) ;
Guerra-Domínguez, Luisa (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Chinea, Anabelle (Hospital Universitario Ramón y Cajal (Madrid)) ;
Garcia Cadenas, Irene (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
López-Corral, Lucía (Hospital Clínico Universitario (Salamanca)) ;
Boix, Francisco (Universidad de Salamanca) ;
López Lorenzo, José Luis (Hospital Universitario Fundación Jiménez Díaz) ;
Humala, Karem (Hospital Universitario La Paz (Madrid)) ;
Duarte, Rafael (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Sampol, Antonia (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Heras, Inmaculada (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Vicario, José Luis (Centro de Transfusión de la Comunidad de Madrid) ;
Balas, Antonio (Centro de Transfusión de la Comunidad de Madrid) ;
Oarbeascoa, Gillen (Hospital General Universitario Gregorio Marañón) ;
Fernández-Caldas, Paula (Hospital General Universitario Gregorio Marañón) ;
Anguita, Javier (Universidad Complutense de Madrid) ;
Kwon, Mi (Universidad Complutense de Madrid) ;
Universitat Autònoma de Barcelona
Donor-specific antibodies (DSAs) are IgG allo-antibodies against mismatched donor HLA molecules and can cause graft failure (GF) in the setting of haploidentical hematopoietic stem cell transplantation (haplo-HSCT). [...]
2023 - 10.3389/fimmu.2023.1165759
Frontiers in immunology, Vol. 14 (may 2023)
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11 p, 1.6 MB |
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia
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Friedberg, Adit (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Pasquini, Lorenzo (Neuroscape, University of California, San Francisco) ;
Diggs, Ryan (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Glaubitz, Erika A. (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Lopez, Lucia (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Illán-Gala, Ignacio (Institut de Recerca Sant Pau) ;
Iaccarino, Leonardo (now with Eli Lilly and Company, Philadelphia, Pennsylvania) ;
La Joie, Renaud (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Mundada, Nidhi (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Knudtson, Marguerite (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Neylan, Kyra (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Brown, Jesse (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Allen, Isabel (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Rankin, Katherine P. (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Bonham, Luke W. (Department of Radiology and Biomedical Imaging, University of California, San Francisco) ;
Yokoyama, Jennifer S. (Department of Radiology and Biomedical Imaging, University of California, San Francisco) ;
Ramos, Eliana M. (Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles) ;
Geschwind, Daniel H. (Institute for Precision Health, University of California, Los Angeles) ;
Spina, Salvatore (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Grinberg, Lea T. (Department of Pathology, University of California, San Francisco) ;
Miller, Zachary A. (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Kramer, Joel H. (University of California. Department of Neurology) ;
Rosen, Howard (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Gorno-Tempini, Maria Luisa (Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco) ;
Rabinovici, Gil (Associate Editor, JAMA Neurology) ;
Seeley, William W. (Department of Pathology, University of California, San Francisco) ;
Miller, Bruce L. (Global Brain Health Institute, University of California, San Francisco, and Trinity College Dublin, Dublin, Ireland) ;
Universitat Autònoma de Barcelona
This case-control study assesses the anatomical and physiological underpinnings of visual artistic creativity in individuals with frontotemporal dementia. What are the neural underpinnings of visual artistic creativity (VAC) in the setting of frontotemporal dementia (FTD)? In this study of 119 patients, VAC occurred early in the course of FTD, was disproportionately observed in patients with temporal lobe-predominant degeneration, and may be associated with damage to brain regions that normally suppress dorsomedial occipital cortex function. [...]
2023 - 10.1001/jamaneurol.2023.0001
JAMA Neurology, Vol. 80 (february 2023) , p. 377-387
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