UAB Digital Repository of Documents 2 records found  Search took 0.01 seconds. 
1.
30 p, 5.9 MB Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury : A Review of the Evidence / Jha, Ruchira M. (University of Pittsburgh) ; Bell, Josh (Biogen (Estats Units d'Amèrica)) ; Citerio, Giuseppe (Ospedale San Gerardo (Itàlia)) ; Hemphill, J. Claude (University of California) ; Kimberly, W. Taylor (Massachusetts General Hospital (Boston)) ; Narayan, Raj K. (North Shore University Hospital) ; Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sheth, Kevin N. (Yale University School of Medicine) ; Simard, J. Marc (University of Maryland School of Medicine) ; Universitat Autònoma de Barcelona
Cerebral edema and contusion expansion are major determinants of morbidity and mortality after TBI. Current treatment options are reactive, suboptimal and associated with significant side effects. First discovered in models of focal cerebral ischemia, there is increasing evidence that the sulfonylurea receptor 1 (SUR1)-Transient receptor potential melastatin 4 (TRPM4) channel plays a key role in these critical secondary injury processes after TBI. [...]
2020 - 10.3390/ijms21020409
International journal of molecular sciences, Vol. 21 (january 2020)  
2.
20 p, 3.7 MB Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion / Gerzanich, Volodymyr (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Stokum, Jesse A. (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Ivanova, Svetlana (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Woo, Seung Kyoon (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Tsymbalyuk, Orest (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Sharma, Amit (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Akkentli, Fatih (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Imran, Ziyan (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Aarabi, Bizhan (Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland) ; Sahuquillo Barris, Juan (Hospital Universitari Vall d'Hebron) ; Simard, J. Marc (Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland) ; Universitat Autònoma de Barcelona
In severe traumatic brain injury (TBI), contusions often are worsened by contusion expansion or hemorrhagic progression of contusion (HPC), which may double the original contusion volume and worsen outcome. [...]
2019 - 10.1089/neu.2018.5986
Journal of Neurotrauma, Vol. 36 (march 2019) , p. 1060-1079  

See also: similar author names
2 Simard, J.
1 Simard, J.M.
11 Simard, Jacques
Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.