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13 p, 1.3 MB Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing / Ferreira, Pedro G. (Centre de Regulació Genòmica) ; Oti, Martin (Federal University of Rio de Janeiro. Institute of Biophysics Carlos Chagas Filho) ; Barann, Matthias (Christians-Albrechts-Universität zu Kiel. Institute of Clinical Molecular Biology) ; Wieland, Thomas (Helmholtz Center Munich. Institute of Human Genetics) ; Ezquina, Suzana (University of São Paulo. Center for Human Genome and Stem-cell research) ; Friedländer, Marc R. (Stockholm University. Science for Life Laboratory) ; Rivas, Manuel A. (University of Oxford. Wellcome Trust Centre for Human Genetics) ; Esteve-Codina, Anna (Centre de Recerca en Agrigenòmica) ; Rosenstiel, Philip (Christians-Albrechts-Universität zu Kiel. Institute of Clinical Molecular Biology) ; Strom, Tim M. (Technische Universität München. Institute of Human Genetics) ; Lappalainen, Tuuli (University of Geneva. Institute for Genetics and Genomics in Geneva) ; Guigó, Roderic (Universitat Pompeu Fabra) ; Sammeth, Michael (National Center of Scientific Computing (Brazil))
Recent advances in the cost-efficiency of sequencing technologies enabled the combined DNA- and RNA-sequencing of human individuals at the population-scale, making genome-wide investigations of the inter-individual genetic impact on gene expression viable. [...]
2016 - 10.1038/srep32406
Scientific reports, Vol. 6 (September 2016) , art. 32406  

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