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Articles, 4 records found
Articles 4 records found  
1.
12 p, 608.0 KB Switching from a ritonavir-boosted protease inhibitor to a dolutegravir-based regimen for maintenance of HIV viral suppression in patients with high cardiovascular risk / Gatell, José Mª (Hospital Clínic i Provincial de Barcelona) ; Assoumou, Lambert (UPMC Univ Paris 06) ; Moyle, Graeme (St Chelsea and Westminster Hospital) ; Waters, Laura (Mortimer Market Center) ; Johnson, Margaret (Royal Free Hospital) ; Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ; Fox, Julie (Guys and St. Thomas Hospital) ; Martinez, Esteban (Hospital Clínic i Provincial de Barcelona) ; Stellbrink, Hans-Jürgen (ICH Study Centrum) ; Guaraldi, Giovanni (University of Modena and Reggio Emilia) ; Masia, Mar (Hospital General Universitario de Elche) ; Gompels, Marl (Southmead Hospital) ; De Wit, Stephane (Université Libre de Bruxelles) ; Florence, Eric (Institute of Tropical Medicine) ; Esser, Stefan (Universitatsklinikum) ; Raffi, François (CHU de Nantes) ; Pozniak, Anton L. (St Chelsea and Westminster Hospital) ; Universitat Autònoma de Barcelona
To compare the efficacy, safety, and impact on lipid fractions of switching from a ritonavir-boosted protease inhibitor (PI/r) to a dolutegravir (DTG) regimen. HIV type 1-infected adults more than 50 years or with a Framingham score more than 10% were eligible if plasma HIV RNA less than 50 copies per ml for at least 24 weeks while on a PI/r regimen. [...]
2017 - 10.1097/QAD.0000000000001675
AIDS, Vol. 31 Núm. 18 (28 2017) , p. 2503-2514  
Detailed record - Creative Commons
2.
4 p, 220.6 KB Integrase strand-transfer inhibitors for treatment of early HIV infection : A case series / Teira, Ramón (Hospital Universitario de Sierrallana) ; Gutierrez, Mª del Mar (Institut d'Investigació Biomèdica Sant Pau) ; Galindo, Pepa (Hospital Clínico Universitario) ; Martínez, Elisa (Complejo Hospitalario Universitario de Albacete) ; Muñoz, Pepa (Hospital de Basurto (Bilbao, Biscaia)) ; de la Fuente, Belén (Hospital Universitario de Cabueñes (Gijón)) ; Téllez, Francisco (Hospital Universitario de Puerto Real) ; Montero, Marta (Hospital Universitari i Politècnic La Fe (València)) ; Universitat Autònoma de Barcelona
This study evaluated whether the interval from the first clinic visit until the start of antiretroviral treatment (ART) was correlated with common parameters of immunological recovery among patients with early HIV infection (EHI). [...]
2019 - 10.1097/MD.0000000000016866
Medicine, Vol. 98 Núm. 35 (january 2019) , p. e16866  
Detailed record - Creative Commons
3.
9 p, 544.7 KB Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir/Abacavir/Lamivudine in Antiretroviral-Naive Adults (SYMTRI) : A Multicenter Randomized Open-Label Study (PReEC/RIS-57) / Podzamczer, Daniel (Hospital Universitari de Bellvitge) ; Micán, R. (Hospital Universitario La Paz (Madrid)) ; Tiraboschi, Juan Manuel (Hospital Universitari de Bellvitge) ; Portilla, J. (Hospital General Universitario de Alicante (Alacant, País Valencià)) ; Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ; Llibre, Josep M.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ribera, E. (Hospital Universitari Vall d'Hebron) ; Vivancos, M.J. (Hospital Universitario Ramón y Cajal (Madrid)) ; Morano, L. (Hospital Álvaro Cunqueiro (Vigo)) ; Masiá, M. (Hospital General Universitario de Elche) ; Gómez, C. (Hospital Universitario Virgen de la Victoria-IBIMA) ; Fanjul, F. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Payeras, A. (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ; Inciarte, Alexy (Hospital Clínic i Provincial de Barcelona) ; Estrada, V. (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ; Rivero, A. (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ; Castro, A. (Complejo Hospitalario Universitario) ; Bernal, Enrique (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ; Vinuesa, D. (Hospital Universitario San Cecilio (Granada)) ; Knobel Freud, Hernando (Hospital del Mar (Barcelona, Catalunya)) ; Troya, J. (Hospital Universitario Infanta Leonor) ; Macías, Juan (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Montero, M. (Hospital Universitari i Politècnic La Fe (València)) ; Sanz, J. (Hospital Universitario de la Princesa (Madrid)) ; Navarro-Alcaraz, Antonio (Hospital Universitari de Bellvitge) ; Caicedo, A. (Ris Red de Investigación en Sida) ; Fernández, G. (Hospital Universitari de Bellvitge) ; Martínez, Esteban (Hospital Clínic i Provincial de Barcelona) ; Moreno, S. (Hospital Universitario Ramón y Cajal (Madrid)) ; Universitat Autònoma de Barcelona
Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) is the reference for combination therapy based on protease inhibitors due to its efficacy, tolerability, and convenience. Head-to-head randomized comparisons between D/C/F/TAF and combination therapy based on integrase inhibitors in antiretroviral-naive patients are lacking. [...]
2022 - 10.1093/ofid/ofab595
Open Forum Infectious Diseases, Vol. 9 Núm. 3 (january 2022) , p. ofab595  
Detailed record - Creative Commons
4.
9 p, 1.7 MB Switching From a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen : A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human Immunodeficiency Virus-infected Individuals / Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Navarro, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jimenez, Montse (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rutsaert, Sofie (Universitair Ziekenhuis Gent) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron) ; De Clercq, Laura (Universitair Ziekenhuis Gent) ; Ribas, Bibiana Planas (Hospital Universitari Vall d'Hebron) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vandekerckhove, Linos (Universitair Ziekenhuis Gent) ; Blanco, Julià (Universitat de Vic - Universitat Central de Catalunya) ; Crespo Casal, Manuel (Instituto de Investigación Sanitaria Galicia Sur) ; Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona
Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted protease inhibitor (PI/r)-based therapy to dolutegravir (DTG)-based therapy. [...]
2018 - 10.1093/cid/ciy1095
Clinical Infectious Diseases, Vol. 69 (december 2018) , p. 1320-1328  
Detailed record - Creative Commons

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