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Results overview: Found 3 records in 0.03 seconds.
Articles, 3 records found
Articles 3 records found  
1.
10 p, 531.5 KB The MacroH2A1.1 - PARP1 Axis at the Intersection Between Stress Response and Metabolism / Hurtado-Bagès, Sarah (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Guberovic, Iva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Universitat Autònoma de Barcelona
The exchange of replication-coupled canonical histones by histone variants endows chromatin with specific features. The replacement of the canonical H2A histone for the histone variant macroH2A is one of the most remarkable epigenetic modifications. [...]
2018 - 10.3389/fgene.2018.00417
Frontiers in genetics, Vol. 9 (october 2018)  
Detailed record - Creative Commons
2.
14 p, 1.7 MB Crown ethers reverse P-glycoprotein-mediated multidrug resistance in cancer cells / Guberovic, Iva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Marjanović, Marko (Ruđer Bošković Institute. Division of Molecular Medicine) ; Mioč, Marija (Ruđer Bošković Institute. Division of Molecular Medicine) ; Ester, Katja (Ruđer Bošković Institute. Division of Molecular Medicine) ; Martin-Kleiner, Irena (Ruđer Bošković Institute. Division of Molecular Medicine) ; Šumanovac Ramljak, Tatjana (Ruđer Bošković Institute. Department of Organic Chemistry and Biochemistry) ; Mlinarić-Majerski, Kata (Ruđer Bošković Institute. Department of Organic Chemistry and Biochemistry) ; Kralj, Marijeta (Ruđer Bošković Institute. Division of Molecular Medicine)
Multidrug resistance (MDR) is a widespread phenomenon exhibited by many cancers and represents a fundamental obstacle for successful cancer treatments. Tumour cells commonly achieve MDR phenotype through overexpression and/or increased activity of ABC transporters. [...]
2018 - 10.1038/s41598-018-32770-y
Scientific reports, Vol. 8 (september 2018)  
Detailed record - Creative Commons
3.
1.9 MB MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD + consumption / Posavec Marjanović, Melanija (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Hurtado-Bagès, Sarah (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Lassi, Maximilian (German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany) ; Valero, Vanesa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Malinverni, Roberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Delage, Hélène (Centre National de la Recherche Scientifique (França)) ; Navarro, Miriam (Universitat Rovira i Virgili) ; Corujo, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Guberovic, Iva (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Douet, Julien (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Gama-Pérez, Pau (Universitat de Barcelona. Departament de Ciències Fisiològiques II) ; Garcia-Roves, Pablo M. (Universitat de Barcelona. Departament de Ciències Fisiològiques II) ; Ahel, Ivan (Sir William Dunn School of Pathology, University of Oxford, Oxford, UK) ; Ladurner, Andreas G. (Biomedical Center Munich (BMC) - Physiological Chemistry, Center for Integrated Protein Science Munich, Munich Cluster for Systems Neurology, Faculty of Medicine, LMU Munich, Planegg-Martinsried, Germany) ; Yanes, Oscar (Universitat Rovira i Virgili) ; Bouvet, Philippe (Université de Lyon, Ecole Normale Supérieure de Lyon) ; Suelves Esteban, Mònica (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Teperino, Raffaele (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Pospisilik, J. Andrew (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Histone variants are structural components of eukaryotic chromatin that can replace replication-coupled histones in the nucleosome. The histone variant macroH2A. 1. 1 contains a macrodomain able to bind NAD + derived metabolites. [...]
2017 - 10.1038/nsmb.3481
Nature structural & molecular biology, Vol. 24 (october 2017) , p. 902-910  
Detailed record -

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