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21 p, 3.3 MB The histone variant macroh2a1 impacts circadian gene expression and cell phenotype in an in vitro model of hepatocellular carcinoma / Carbone, Annalucia (Fondazione IRCCS Casa Sollievo della Sofferenza) ; De Santis, Elisabetta (Fondazione IRCCS Casa Sollievo della Sofferenza) ; Cela, Olga (University of Foggia) ; Giambra, Vincenzo (Fondazione IRCCS Casa Sollievo della Sofferenza) ; Miele, Luca (Catholic University of the Sacred Heart) ; Marrone, Giuseppe (Catholic University of the Sacred Heart) ; Grieco, Antonio (Catholic University of the Sacred Heart) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Capitanio, Nazzareno (University of Foggia) ; Mazza, Tommaso (Fondazione IRCCS Casa Sollievo della Sofferenza) ; Mazzoccoli, Gianluigi (Fondazione IRCCS Casa Sollievo della Sofferenza)
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. A foremost risk factor for HCC is obesity/metabolic syndrome-related non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), which is prompted by remarkable changes in transcription patterns of genes enriching metabolic, immune/inflammatory, and circadian pathways. [...]
2021 - 10.3390/biomedicines9081057
Biomedicines, Vol. 9 Núm. 8 (august 2021) , p. 1057  
Detailed record - Creative Commons

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