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9 p, 612.9 KB |
Bariatric surgery increases the rate of major fracture : self-controlled case series study in Clinical Practice Research Datalink
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Robinson, Danielle E. (University of Oxford) ;
Douglas, Ian (London School of Hygiene & Tropical) ;
Tan, Garry D. (The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre) ;
Delmestri, Antonella (University of Oxford) ;
Judge, Andrew (University of Bristol) ;
Cooper, Cyrus (University of Oxford) ;
Javaid, M. Kassim (University of Southampton) ;
Strauss, Victoria Y. (University of Oxford) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
Conflicting results exist about the relationship between bariatric surgery and fracture risk. Also, prediction of who is at increased risk of fracture after bariatric surgery is not currently available. [...]
2021 -  10.1002/jbmr.4405
Journal of Bone and Mineral Research, Vol. 36 (july 2021) , p. 2153-2161
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11 p, 548.2 KB |
Estimating the Incidence and Key Risk Factors of Cardiovascular Disease in Patients at High Risk of Imminent Fracture Using Routinely Collected Real-World Data From the
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Pineda-Moncusí, Marta (University of Oxford) ;
El-Hussein, Leena (University of Oxford) ;
Delmestri, Antonella (University of Oxford) ;
Cooper, Cyrus (University of Southampton) ;
Moayyeri, Alireza (UCB Biopharma Sprl) ;
Libanati, Cesar (UCB Biopharma Sprl) ;
Toth, Emese (UCB Biopharma Sprl) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Khalid, Sara (University of Oxford) ;
Universitat Autònoma de Barcelona
The objective of this work was to estimate the incidence rate of cardiovascular disease (CVD) events (myocardial infarction, stroke, or CVD death) at 1 year among three cohorts of patients at high risk of fracture (osteoporosis, previous fracture, and anti-osteoporosis medication) and to identify the key risk factors of CVD events in these three cohorts. [...]
2022 - 10.1002/jbmr.4648
Journal of Bone and Mineral Research, Vol. 37 (september 2022) , p. 1986-1996
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2 p, 74.0 KB |
Corrigendum : Transmissibility, hospitalization, and intensive care admissions due to omicron compared to delta variants of SARS-CoV-2 in Catalonia: A cohort study and ecological analysis
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Català, Martí (University of Oxford) ;
Coma, Ermengol (Institut Català de la Salut) ;
Alonso Muñoz, Sergio (Universitat Politècnica de Catalunya) ;
Andrés, Cristina (Hospital Universitari Vall d'Hebron) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Antón, Andrés (Hospital Universitari Vall d'Hebron) ;
Bordoy, Antoni E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fina, Francesc (Institut Català de la Salut) ;
Martró, Elisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Medina, Manuel (Institut Català de la Salut) ;
Mora, Núria (Institut Català de la Salut) ;
Saludes, Verónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prats, Clara (Universitat Politècnica de Catalunya) ;
Prieto-Alhambra, Daniel (University of Oxford) ;
Alvarez-Lacalle, Enrique (Universitat Politècnica de Catalunya) ;
Universitat Autònoma de Barcelona
We aim to compare the severity of infections between omicron and delta variants in 609,352 SARS-CoV-2 positive cases using local hospitalization, vaccination, and variants data from the Catalan Health Care System (which covers around 7. [...]
2022 - 10.3389/fpubh.2022.1060328
Frontiers in Public Health, Vol. 10 (november 2022)
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0 p, 2.5 MB |
Transmissibility, hospitalization, and intensive care admissions due to omicron compared to delta variants of SARS-CoV-2 in Catalonia : A cohort study and ecological analysis
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Català, Martí (University of Oxford. Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences) ;
Coma, Ermengol (Institut Català de la Salut) ;
Alonso Muñoz, Sergio (Universitat Politècnica de Catalunya. Departament de Física) ;
Andrés, Cristina (Instituto de Salud Carlos III) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Antón, Andrés (Instituto de Salud Carlos III) ;
Bordoy, Antoni E. (Instituto de Salud Carlos III) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Fina, Francesc (Institut Català de la Salut) ;
Martró, Elisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Medina, Manuel (Institut Català de la Salut) ;
Mora, Núria (Institut Català de la Salut) ;
Saludes, Verónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prats, Clara (Universitat Politècnica de Catalunya. Departament de Física) ;
Prieto-Alhambra, Daniel (University of Oxford. Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences) ;
Alvarez-Lacalle, Enrique (Universitat Politècnica de Catalunya. Departament de Física)
We aim to compare the severity of infections between omicron and delta variants in 609,352 SARS-CoV-2 positive cases using local hospitalization, vaccination, and variants data from the Catalan Health Care System (which covers around 7. [...]
2022 - 10.3389/fpubh.2022.961030
Frontiers in Public Health, Vol. 10 (August 2022)
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24 p, 1.5 MB |
Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group
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Chotiyarnwong, P. (Mahidol University) ;
McCloskey, E. V. (University of Sheffield) ;
Harvey, N. C. (University of Southampton) ;
Lorentzon, M. (Australian Catholic University) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona) ;
Abrahamsen, Bo (Holbæk Hospital (Dinamarca)) ;
Adachi, Jonathan D (St Joseph's Healthcare-McMaster University) ;
Borgström, F. (Karolinska Institutet (Estocolm, Suècia)) ;
Bruyère, Olivier (Université de Liège) ;
Carey, J. J. (Galway University Hospitals) ;
Clark, P. (Universidad Nacional Autónoma de México) ;
Cooper, Cyrus (University of Southampton) ;
Curtis, E. M. (University of Southampton) ;
Dennison, E. M (University of Southampton) ;
Diaz-Curiel, Manuel (Hospital Universitario Fundación Jiménez Díaz) ;
Dimai, Hans Peter (Medical University of Graz) ;
Grigorie, D. (National Institute of Endocrinology) ;
Hiligsmann, M. (Maastricht University) ;
Khashayar, P. (Imec and Ghent University) ;
Lewiecki, E. M. (New Mexico Clinical Research & Osteoporosis Center) ;
Lips, P. (Vrije Universiteit Amsterdam) ;
Lorenc, R. S. (Multidisciplinary Osteoporosis Forum (Polònia)) ;
Ortolani, S. (IRCCS Istituto Auxologico (Itàlia)) ;
Papaioannou, A. (GERAS Centre for Aging Research (Canadà)) ;
Silverman, Stuart (Cedars-Sinai Medical Center) ;
Sosa-Henríquez, Manuel (Universidad de Las Palmas de Gran Canaria) ;
Szulc, P. (Hôpital Edouard Herriot (França)) ;
Ward, K. A. (University of Southampton) ;
Yoshimura, N. (University of Tokyo) ;
Kanis, John A (Australian Catholic University)
The IOF Epidemiology and Quality of Life Working Group has reviewed the potential role of population screening for high hip fracture risk against well-established criteria. The report concludes that such an approach should strongly be considered in many health care systems to reduce the burden of hip fractures. [...]
2022 - 10.1007/s11657-022-01117-6
Archives of Osteoporosis, Vol. 17 (june 2022)
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10 p, 451.3 KB |
Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events : population based cohort and self-controlled case series analysis
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Li, Xintong (University of Oxford) ;
Raventós, Berta (Universitat Autònoma de Barcelona) ;
Roel, Elena (Universitat Autònoma de Barcelona) ;
Pistillo, Andrea (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Martinez-Hernandez, Eugenia (Hospital Clínic i Provincial de Barcelona) ;
Delmestri, Antonella (University of Oxford) ;
Reyes, Carlen (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Strauss, Victoria (University of Oxford) ;
Prieto-Alhambra, Daniel (Erasmus University Medical Center) ;
Burn, Edward (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Duarte-Salles, Talita 1985- (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
To study the association between covid-19 vaccines, SARS-CoV-2 infection, and risk of immune mediated neurological events. Population based historical rate comparison study and self-controlled case series analysis. [...]
2022 - 10.1136/bmj-2021-068373
The BMJ, Vol. 376 (march 2022)
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7 p, 785.6 KB |
Comparative effectiveness and safety of homologous two-dose ChAdOx1 versus heterologous vaccination with ChAdOx1 and BNT162b2
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Hermosilla, Eduardo (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Coma, Ermengol (Institut Català de la Salut) ;
Xie, Junqing (University of Oxford) ;
Feng, Shuo (University of Oxford) ;
Cabezas Peña, Carmen (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Méndez-Boo, Leonardo (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Fina, Francesc (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Balló, Elisabet (Institut Català de la Salut) ;
Martínez, Montserrat (Generalitat de Catalunya. Departament de Salut) ;
Medina-Peralta, Manuel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Argimon, Josep Maria (Generalitat de Catalunya. Departament de Salut) ;
Prieto-Alhambra, Daniel (University of Oxford) ;
Universitat Autònoma de Barcelona
Small trials have suggested that heterologous vaccination with first-dose ChAdOx1 and second-dose BNT162b2 may generate a better immune response than homologous vaccination with two doses of ChAdOx1. [...]
2022 - 10.1038/s41467-022-29301-9
Nature communications, Vol. 13 (march 2022)
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11 p, 902.4 KB |
Comparison of Risk of Osteoporotic Fracture in Denosumab vs Alendronate Treatment Within 3 Years of Initiation
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Pedersen, Alma B. (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Heide-Jørgensen, Uffe (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Sørensen, Henrik T. (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona) ;
Ehrenstein, Vera (Aarhus University Hospital (Aarhus, Dinamarca))
What is the real-world risk of fracture for patients treated with denosumab compared with those treated with alendronate? In this Danish cohort study including 4624 individuals treated with denosumab and 87 731 individuals treated with alendronate, 3-year cumulative incidence of hip fracture was 3. [...]
2019 - 10.1001/jamanetworkopen.2019.2416
JAMA network open, Vol. 2 (april 2019)
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13 p, 619.1 KB |
Use of dialysis, tracheostomy, and extracorporeal membrane oxygenation among 842,928 patients hospitalized with COVID-19 in the United States
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Burn, Edward (Centre for Statistics in Medicine, University of Oxford) ;
Sena, Anthony G. (Department of Medical Informatics, Erasmus University Medical Center (Holanda)) ;
Prats-Uribe, Albert (University of Oxford. Centre for Statistics in Medicine) ;
Spotnitz, Matthew (Department of Biomedical Informatics, Columbia University) ;
DuVall, Scott (University of Utah School of Medicine) ;
Lynch, Kristine E. (Department of Internal Medicine, University of Utah School of Medicine) ;
Matheny, Michael E. (Department of Biomedical Informatics, Vanderbilt University Medical Center) ;
Nyberg, Fredrik (School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg) ;
Ahmed, Waheed-Ul-Rahman (College of Medicine and Health, University of Exeter) ;
Alser, Osaid (Massachusetts General Hospital (Boston)) ;
Alghoul, Heba (Faculty of Medicine, Islamic University of Gaza, Palestine) ;
Alshammari, Thamir (Medication Safety Research Chair, King Saud University) ;
Zhang, Lin (School of Population and Global Health, The University of Melbourne) ;
Casajust, Paula (Trial Form Support (Barcelona)) ;
Areia, Carlos (Nuffield Department of Clinical Neurosciences, University of Oxford) ;
Shah, Karishma (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre) ;
Reich, Christian (Real World Solutions (Estats Units d'Amèrica)) ;
Blacketer, Clair (Janssen Research & Development (Estats Units d'Amèrica)) ;
Andryc, Alan (Janssen Research & Development (Estats Units d'Amèrica)) ;
Fortin, Stephen (Janssen Research & Development (Estats Units d'Amèrica)) ;
Natarajan, Karthik (Department of Biomedical Informatics, Columbia University) ;
Gong, Mengchun (Southern Medical University, Guangzhou, China) ;
Golozar, Asieh (Johns Hopkins Bloomberg School of Public Health) ;
Morales, Daniel (Division of Population Health and Genomics, University of Dundee) ;
Rijnbeek, Peter (Department of Medical Informatics, Erasmus University Medical Center) ;
Subbian, Vignesh (College of Engineering, The University of Arizona, Tucson) ;
Roel, Elena (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Recalde, Martina (Universitat Autònoma de Barcelona) ;
Lane, Jennifer C. E. (Centre for Statistics in Medicine, University of Oxford) ;
Vizcaya, David (Bayer Pharmaceuticals (Barcelona)) ;
Posada, Jose D. (Department of Medicine, Stanford University) ;
Shah, Nigam H. (Department of Medicine, Stanford University) ;
Jonnagaddala, Jitendra (School of Public Health and Community Medicine (Austràlia)) ;
Lai, Lana Yin Hui (University of Manchester) ;
Avilés-Jurado, Francesc Xavier (Agència de Gestió d'Ajuts Universitaris i de Recerca) ;
Hripcsak, George (Department of Biomedical Informatics, Columbia University) ;
Suchard, Marc A. (Department of Biostatistic, UCLA Fielding School of Public Health, University of California) ;
Ranzani, Otavio T. (Pulmonary Division, Heart Institute Universidade de Sao Paulo) ;
Ryan, Patrick (Columbia University) ;
Prieto-Alhambra, Daniel (Centre for Statistics in Medicine, University of Oxford) ;
Kostka, Kristin (Real World Solutions (Estats Units d'Amèrica)) ;
Duarte-Salles, Talita 1985- (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
To estimate the proportion of patients hospitalized with COVID-19 who undergo dialysis, tracheostomy, and extracorporeal membrane oxygenation (ECMO). A network cohort study. Seven databases from the United States containing routinely-collected patient data: HealthVerity, Premier, IQVIA Hospital CDM, IQVIA Open Claims, Optum EHR, Optum SES, and VA-OMOP. [...]
2021 - 10.1101/2020.11.25.20229088
medRxiv, february 2021
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25 p, 727.1 KB |
Characteristics, outcomes, and mortality amongst 133,589 patients with prevalent autoimmune diseases diagnosed with, and 48,418 hospitalised for COVID-19 : a multinational distributed network cohort analysis
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Tan, Eng Hooi (Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford) ;
Sena, Anthony G. (Department of Medical Informatics, Erasmus University Medical Center (Holanda)) ;
Prats-Uribe, Albert (University of Oxford. Centre for Statistics in Medicine) ;
You, Seng Chan (Department of Biomedical Informatics, Ajou University School of Medicine (Corea)) ;
Ahmed, Waheed-Ul-Rahman (College of Medicine and Health, University of Exeter) ;
Kostka, Kristin (Real World Solutions (Estats Units d'Amèrica)) ;
Reich, Christian (Real World Solutions (Estats Units d'Amèrica)) ;
Duvall, Scott L. (Department of Internal Medicine, University of Utah School of Medicine) ;
Lynch, Kristine E. (Department of Internal Medicine, University of Utah School of Medicine) ;
Matheny, Michael E. (Department of Biomedical Informatics, Vanderbilt University Medical Center) ;
Duarte-Salles, Talita 1985- (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Bertolin, Sergio Fernandez (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Hripcsak, George (New York-Presbyterian Hospital) ;
Natarajan, Karthik (New York-Presbyterian Hospital) ;
Falconer, Thomas (Columbia University. Department of Biomedical Informatics) ;
Spotnitz, Matthew (Columbia University. Department of Biomedical Informatics) ;
Ostropolets, Anna (Columbia University. Department of Biomedical Informatics) ;
Blacketer, Clair (Department of Medical Informatics, Erasmus University Medical Center (Holanda)) ;
Alshammari, Thamir (Medication Safety Research Chair, King Saud Univeristy) ;
Alghoul, Heba (Faculty of Medicine, Islamic University of Gaza) ;
Alser, Osaid (Massachusetts General Hospital (Estats Units d'Amèrica)) ;
Lane, Jennifer C. E. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford) ;
Dawoud, Dalia M. (Cairo University, Faculty of Pharmacy, Cairo, Egypt) ;
Shah, Karishma (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford) ;
Yang, Yue (DHC Technologies) ;
Zhang, Lin (Melbourne School of Population and Global Health, The University of Melbourne, Victoria 3015, Australia) ;
Areia, Carlos (Nuffield Department of Clinical Neurosciences, University of Oxford) ;
Golozar, Asieh (Departament of Epidemiology, Johns Hopkins School of Public) ;
Relcade, Martina (Universitat Autònoma de Barcelona) ;
Casajust, Paula (Trial Form Support (Barcelona)) ;
Jonnagaddala, Jitendra (School of Public Health and Community Medicine (Austràlia)) ;
Subbian, Vignesh (College of Engineering, The University of Arizona Tucson) ;
Vizcaya, David (Bayer Pharmaceuticals (Barcelona)) ;
Lai, Lana Y. H. (School of Medical Sciences, University of Manchester) ;
Nyberg, Fredrik (School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg (Suècia)) ;
Morales, Daniel R. (Division of Population Health Sciences, University of Dundee) ;
Posada, Jose D. (Stanford Center for Biomedical Informatics Research, Department of Medicine, School of Medicine, Stanford University) ;
Shah, Nigam H. (Stanford Center for Biomedical Informatics Research, Department of Medicine, School of Medicine, Stanford University) ;
Gong, Mengchun (Health Management Institute, Southern Medical University) ;
Vivekanantham, Arani (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford) ;
Abend, Aaron (Autoimmune Registry (Regne Unit)) ;
Minty, Evan P. (O'Brien School for Public Health, Faculty of Medicine, University of Calgary) ;
Suchard, Marc (Department of Biostatistics, University of California) ;
Rijnbeek, Peter (Department of Medical Informatics, Erasmus University Medical Center (Holanda)) ;
Ryan, Patrick B. (Department of Biomedical Informatics, Columbia University) ;
Prieto-Alhambra, Daniel (Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford) ;
Universitat Autònoma de Barcelona
Patients with autoimmune diseases were advised to shield to avoid COVID-19, but information on their prognosis is lacking. We characterised 30-day outcomes and mortality after hospitalisation with COVID-19 among patients with prevalent autoimmune diseases, and compared outcomes after hospital admissions among similar patients with seasonal influenza. [...]
2020 - 10.1101/2020.11.24.20236802
medRxiv, november 2020
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