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795.1 KB |
Genetic and phenotypic spectrum associated with IFIH1 gain-of-function
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Rice, Gillian I. (University of Manchester) ;
Park, Sehoon (Boston Children's Hospital) ;
Gavazzi, Francesco (Children's Hospital of Philadelphia) ;
Adang, Laura A. (Children's Hospital of Philadelphia) ;
Ayuk, Loveline A. (Dumfries and Galloway Royal Infirmary) ;
Eyck, Lien Van (Institut Imagine (Paris, França)) ;
Seabra, Luis (Institut Imagine (Paris, França)) ;
Barrea, Christophe (Université de Liège) ;
Battini, Roberta (IRCCS Fondazione Stella Maris) ;
Belot, Alexandre (Université de Lyon) ;
Berg, Stefan (The Queen Silvia Children's Hospital) ;
de Villemeur, Thierry Billette (Sorbonne Université) ;
Bley, Annette E. (University Children's Hospital) ;
Blumkin, Lubov (Tel-Aviv University) ;
Boespflug-Tanguy, Odile (Centre de Référence Maladies Rares "Leucodystrophies") ;
Briggs, Tracy A. (St Mary's Hospital) ;
Brimble, Elise (Stanford University School of Medicine) ;
Dale, Russell C. (University of Sydney) ;
Darin, Niklas (The Queen Silvia Children's Hospital) ;
Debray, François-Guillaume (Université de Liège) ;
De Giorgis, Valentina (IRCCS Mondino Foundation) ;
Denecke, Jonas (University Medical Center Hamburg Eppendorf) ;
Doummar, Diane (Hôpital Armand Trousseau) ;
Hagelsrum, Gunilla Drake af (PeThe Queen Silvia Children's Hospital) ;
Eleftheriou, Despina (University College London (UCL)) ;
Estienne, Margherita (Istituto Neurologico Carlo Besta) ;
Fazzi, Elisa (Department of Experimental and Clinical Sciences, University of Brescia, Brescia, Italy) ;
Feillet, François (Service de Médecine Infantile, Centre de Référence des maladies métaboliques de Nancy, CHU Brabois Enfants, Unité INSERM NGERE U1256, Nancy, France) ;
Galli, Jessica (Department of Experimental and Clinical Sciences, University of Brescia, Brescia, Italy) ;
Hartog, Nicholas (Department of Allergy/Immunology, Spectrum Health Helen Devos Children's Hospital, Michigan State University College of Human Medicine, East Lansing, Michigan) ;
Harvengt, Julie (Department of Medical Genetics, CHU & University of Liège, Gembloux, Belgium) ;
Heron, Bénédicte (Service de Neuropédiatrie, Centre Référence des Maladies Lysosomales, Hôpital Trousseau, Paris, France) ;
Heron, Delphine (UF Génétique Médicale et Centre de Référence "Déficiences Intellectuelles", Groupe Hospitalier Pitié-Salpêtrière, Paris, France) ;
Kelly, Diedre A. (The Liver Unit, Birmingham Women's and Children's Hospital NHS Foundation Trust, Birmingham, United Kingdom) ;
Lev, Dorit (Metabolic Neurogenetic Service, Wolfson Medical Center, The Rina Mor Institute of Medical Genetics, Holon, Israel) ;
Levrat, Virginie (Service de pédiatrie, Centre Hospitalier Annecy Genevois, Pringy, France) ;
Livingston, John H. (Department of Paediatric Neurology, Leeds General Infirmary, Leeds, United Kingdom) ;
Marti, Itxaso (Pediatric Neurology, Hospital Universitario Donostia, Universidad del País Vasco UPV-EHU, San Sebastian, Spain) ;
Mignot, Cyril (Departement de Génétique & Centre de Référence Déficience Intellectuelle de cause rare, GH Pitié-Sapêtrière, Paris, France) ;
Mochel, Fanny (Institut du Cerveau et de la Moelle épinière, INSERM U 1127, Sorbonne Universités, Paris, France) ;
Nougues, Marie-Christine (Service de Neuropédiatrie, GHUEP, Hôpital Armand Trousseau, APHP, Paris, France) ;
Oppermann, Ilena (University Children's Hospital, University Medical Center Hamburg Eppendorf, Hamburg, Germany) ;
Pérez-Dueñas, Belén (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Popp, Bernt (Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany) ;
Rodero, Mathieu P. (Laboratory of Neurogenetics and Neuroinflammation, Institut Imagine, Paris, France) ;
Rodriguez, Diana (Service de Neuropédiatrie, Hôpital Trousseau, Groupe Hospitalier HUEP, Inserm U1141, Paris, France) ;
Saletti, Veronica (Developmental Neurology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy) ;
Sharpe, Cia (Paediatric Neurology, Starship Children's Hospital, Auckland, New Zealand) ;
Tonduti, Davide (Pediatric Neurology Unit, V. Buzzi Children's Hospital, Milan, Italy) ;
Vadlamani, Gayatri (Department of Paediatric Neurology, Leeds General Infirmary, Leeds, United Kingdom) ;
Haren, Keith Van (Department of Neurology, Stanford University School of Medicine, Stanford, California) ;
Vila, Miguel Tomas (Neuropediatría, Hospital Universitari i Pôlitecnic La Fe, Valencia, Spain) ;
Vogt, Julie (West Midlands Regional Clinical Genetics Service and Birmingham Health Partners, Birmingham Women's and Children's Hospitals NHS Foundation Trust, Birmingham, United Kingdom) ;
Wassmer, Evangeline (Department of Paediatric Neurology, Birmingham Women's and Children's Hospitals NHS Foundation Trust, Birmingham, United Kingdom) ;
Wiedemann, Arnaud (Service de Médecine Infantile, Centre de Référence des maladies métaboliques de Nancy, CHU Brabois Enfants, Unité INSERM NGERE U1256, Nancy, France) ;
Wilson, Callum J. (National Metabolic Service, Starship Children's Hospital, Auckland, New Zealand) ;
Zerem, Ayelet (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ;
Zweier, Christiane (Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany) ;
Zuberi, Sameer M. (School of Medicine, University of Glasgow, Glasgow, United Kingdom) ;
Orcesi, Simona (Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy) ;
Vanderver, Adeline L. (Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania) ;
Hur, Sun (Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, Massachusetts) ;
Crow, Yanick J. (Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom) ;
Universitat Autònoma de Barcelona
IFIH1 gain-of-function has been reported as a cause of a type I interferonopathy encompassing a spectrum of autoinflammatory phenotypes including Aicardi-Goutières syndrome and Singleton Merten syndrome. [...]
2020 -  10.1002/humu.23975
Human mutation, Vol. 41 (january 2020) , p. 837-849
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7 p, 443.9 KB |
Acute tubulointerstitial nephritis induced by checkpoint inhibitors versus classical acute tubulointerstitial nephritis : are they the same disease?
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Draibe, Juliana B (Hospital Universitari de Bellvitge) ;
García-Carro, Clara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martinez-Valenzuela, Laura (Hospital Universitari de Bellvitge) ;
Agraz Pamplona, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fulladosa, Xavier (Hospital Universitari de Bellvitge) ;
Bolufer, Monica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tango, Ariel (Hospital Universitari de Bellvitge) ;
Torras, Joan (Universitat de Barcelona) ;
Soler, María José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
The incidence of acute tubulointerstitial nephritis (ATIN) related to drugs has dramatically increased over recent years. A new subtype of ATIN, apparently different from classical drug-related ATIN, has emerged that has been related to the administration of immune checkpoint inhibitors (ICIs). [...]
2020 - 10.1093/ckj/sfaa027
Clinical Kidney Journal, Vol. 14 (may 2020) , p. 884-890
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28 p, 649.1 KB |
COVID-19 in patients with autoimmune diseases : characteristics and outcomes in a multinational network of cohorts across three countries
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Tan, Eng Hooi (Rheumatology, and Musculoskeletal Sciences, University of Oxford. Centre for Statistics in Medicine) ;
Sena, Anthony G (Erasmus University Medical Center) ;
Prats-Uribe, Albert (Rheumatology, and Musculoskeletal Sciences, University of Oxford. Centre for Statistics in Medicine) ;
You, Seng Chan (Suwon) ;
Ahmed, Waheed-Ul-Rahman (University of Exeter) ;
Kostka, Kristin (Real World Solutions) ;
Reich, Christian (Real World Solutions) ;
Duvall, Scott L (Salt Lake City) ;
Lynch, Kristine E (Salt Lake City) ;
Matheny, Michael E (Vanderbilt University Medical Center) ;
Duarte-Salles, Talita (Institut d'Investigació en Atenció Primària Jordi Gol) ;
Bertolin, Sergio Fernandez (Institut d'Investigació en Atenció Primària Jordi Gol) ;
Hripcsak, George (New York-Presbyterian Hospital) ;
Natarajan, Karthik (New York-Presbyterian Hospital) ;
Falconer, Thomas (Columbia University) ;
Spotnitz, Matthew (Columbia University) ;
Ostropolets, Anna (Columbia University) ;
Blacketer, Clair (Erasmus University Medical Center) ;
Alshammari, Thamir M (King Saud Univeristy. Medication Safety Research Chair) ;
Alghoul, Heba (Islamic University of Gaza) ;
Alser, Osaid (Harvard Medical School. Massachusetts General Hospital) ;
Lane, Jennifer C E (Rheumatology, and Musculoskeletal Sciences, University of Oxford. Centre for Statistics in Medicine) ;
Dawoud, Dalia M (Cairo University) ;
Shah, Karishma (Botnar Research Centre. University of Oxford. Rheumatology) ;
Yang, Yue (DHC Technologies Co) ;
Zhang, Lin (The University of Melbourne) ;
Areia, Carlos (University of Oxford) ;
Golozar, Asieh (Departament of Epidemiology) ;
Recalde, Martina (Institut d'Investigació en Atenció Primària Jordi Gol) ;
Casajust, Paula (Real-World Evidence) ;
Jonnagaddala, Jitendra (UNSW Sydney) ;
Subbian, Vignesh (The University of Arizona Tucson) ;
Vizcaya, David (Bayer Pharmaceuticals) ;
Lai, Lana Y H (University of Manchester) ;
Nyberg, Fredrik (University of Gothenburg. Sahlgrenska Academy. Institute of Medicine) ;
Morales, Daniel R (University of Dundee) ;
Posada, Jose D (Stanford University. Stanford Center for Biomedical Informatics Research) ;
Shah, Nigam H (Stanford University. Stanford Center for Biomedical Informatics Research) ;
Gong, Mengchun (Southern Medical University. Health Management Institute) ;
Vivekanantham, Arani (Botnar Research Centre. University of Oxford. Rheumatology) ;
Abend, Aaron (Autoimmune Registry Inc) ;
Minty, Evan P (University Drive NW. University of Calgary. O'Brien School for Public Health) ;
Suchard, Marc (University of California) ;
Rijnbeek, Peter (Erasmus University Medical Center) ;
Ryan, Patrick B (Columbia University) ;
Prieto-Alhambra, Daniel (Rheumatology, and Musculoskeletal Sciences, University of Oxford. Centre for Statistics in Medicine) ;
Universitat Autònoma de Barcelona
Patients with autoimmune diseases were advised to shield to avoid COVID-19, but information on their prognosis is lacking. We characterised 30-day outcomes and mortality after hospitalisation with COVID-19 among patients with prevalent autoimmune diseases, and compared outcomes after hospital admissions among similar patients with seasonal influenza. [...]
2021 - 10.1093/rheumatology/keab250
Rheumatology, march 2021
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14 p, 1.2 MB |
Diagnostic Utility of Measuring Cerebral Atrophy in the Behavioral Variant of Frontotemporal Dementia and Association With Clinical Deterioration
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Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ;
Falgàs, Neus (Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Barcelona, Spain) ;
Friedberg, Adit (Atlantic Fellow for Equity in Brain Health, Department of Neurology, University of California, San Francisco) ;
Castro-Suárez, Sheila (Atlantic Fellow for Equity in Brain Health, Department of Neurology, University of California, San Francisco) ;
Keret, Ophir (Atlantic Fellow for Equity in Brain Health, Department of Neurology, University of California, San Francisco) ;
Rogers, Nicole (Atlantic Fellow for Equity in Brain Health, Department of Neurology, University of California, San Francisco) ;
Oz, Didem (Atlantic Fellow for Equity in Brain Health, Department of Neurology, University of California, San Francisco) ;
Nigro, Salvatore (Neuroscience Centre, Magna Graecia University, Catanzaro, Italy) ;
Quattrone, Andrea (Department of Medical and Surgical Sciences, Institute of Neurology, Magna Graecia University, Catanzaro, Italy) ;
Quattrone, Aldo (Neuroimaging Research Unit, Institute of Molecular Bioimaging and Physiology, National Research Council, Catanzaro, Italy) ;
Wolf, Amy (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Younes, Kyan (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Santos-Santos, Miguel (Institut d'Investigació Biomèdica Sant Pau) ;
Borrego-Écija, Sergi (Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Barcelona, Spain) ;
Cobigo, Yann (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ;
Lladó, Albert (Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Barcelona, Spain) ;
Sánchez-Valle, Raquel (Alzheimer's Disease and Other Cognitive Disorders Unit, Department of Neurology, Hospital Clínic, Institut d'Investigació Biomèdica August Pi i Sunyer, University of Barcelona, Barcelona, Spain) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Grinberg, Lea T. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Spina, Salvatore (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Kramer, Joel H. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Rabinovici, Gil D. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Boxer, Adam (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Gorno Tempini, Maria Luisa (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Miller, Bruce L. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Seeley, William W. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Rosen, Howard J. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Perry, David C. (Memory and Aging Center, Department of Neurology, University of California, San Francisco) ;
Universitat Autònoma de Barcelona
Can widely available measures of atrophy on magnetic resonance imaging increase diagnostic certainty of underlying frontotemporal lobar degeneration (FTLD) and estimate clinical deterioration in the behavioral variant of frontotemporal dementia (bvFTD)? This diagnostic/prognostic study investigated the clinical utility of 5 validated visual atrophy scales (VAS) and the Magnetic Resonance Parkinsonism Index. [...]
2021 - 10.1001/jamanetworkopen.2021.1290
JAMA network open, Vol. 4 (march 2021)
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6 p, 431.4 KB |
Relationship between adiponectin, TNFα, and SHBG in prepubertal children with obesity
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Ramon-Krauel, Marta (Hospital Sant Joan de Déu. Endocrinology Department, Institut de Recerca Sant Joan de Déu) ;
Leal-Witt, María Jesús (Hospital Sant Joan de Déu. Endocrinology Department, Institut de Recerca Sant Joan de Déu) ;
Osorio-Conles, Óscar (Hospital Sant Joan de Déu. Endocrinology Department, Institut de Recerca Sant Joan de Déu) ;
Amat-Bou, Montse (Hospital Sant Joan de Déu. Endocrinology Department, Institut de Recerca Sant Joan de Déu) ;
Lerin, Carles (Hospital Sant Joan de Déu. Endocrinology Department, Institut de Recerca Sant Joan de Déu) ;
Martínez Selva, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Sex hormone-binding globulin (SHBG) levels are low in adult subjects with obesity when compared to normal-weight individuals. Obesity is associated with higher tumor necrosis factor alpha (TNFα) plasma levels and lower adiponectin levels. [...]
2021 - 10.1186/s40348-021-00113-z
Molecular and Cellular Pediatrics, Vol. 8 (march 2021)
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10 p, 563.7 KB |
Mortality risk prediction in elderly patients with cardiogenic shock : results from the CardShock study
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Hongisto, Mari (Helsinki University Hospital) ;
Lassus, Johan (Helsinki University Hospital) ;
Tarvasmäki, Tuukka (Helsinki University Hospital) ;
Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ;
Sans-Rosello, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Tolppanen, Heli (Helsinki University Hospital) ;
Kataja, Anu (Helsinki University Hospital) ;
Jäntti, Toni (Helsinki University Hospital) ;
Sabell, Tuija (Helsinki University Hospital) ;
Lindholm, Matias Greve (Zealand University Hospital) ;
Banaszewski, Marek (National Institute of Cardiology) ;
Silva Cardoso, Jose (University of Porto, São João University Medical Centre) ;
Parissis, John (Attikon University Hospital) ;
Di Somma, Salvatore (Sapienza University of Rome) ;
Carubelli, Valentina (University and Civil Hospital of Brescia) ;
Jurkko, Raija (Helsinki University Hospital) ;
Masip, Josep (Hospital Sant Joan Despi Moisès Broggi, Consorci Sanitari Integral, University of Barcelona) ;
Harjola, Veli-Pekka (Helsinki University Hospital) ;
Universitat Autònoma de Barcelona
This study aimed to assess the utility of contemporary clinical risk scores and explore the ability of two biomarkers [growth differentiation factor-15 (GDF-15) and soluble ST2 (sST2)] to improve risk prediction in elderly patients with cardiogenic shock. [...]
2021 - 10.1002/ehf2.13224
ESC Heart Failure, Vol. 8 (january 2021) , p. 1398-1407
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10 p, 1.2 MB |
Correlation Between Respiratory Accessory Muscles and Diaphragm Pillars MRI and Pulmonary Function Test in Late-Onset Pompe Disease Patients
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Reyes-Leiva, David
0000-0001-6983-7130 (Institut d'Investigació Biomèdica Sant Pau) ;
Alonso-Pérez, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Mayos, Mercedes (Institut d'Investigació Biomèdica Sant Pau) ;
Nuñez-Peralta, Claudia Alejandra (Institut d'Investigació Biomèdica Sant Pau) ;
Llauger, Jaume (Institut d'Investigació Biomèdica Sant Pau) ;
Belmonte Jimeno, Izaskun (Institut d'Investigació Biomèdica Sant Pau) ;
Pedrosa-Hernández, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Segovia, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Objectives: Pompe disease is a rare genetic disease produced by mutations in the GAA gene leading to progressive skeletal and respiratory muscle weakness. T1-weighted magnetic resonance imaging is useful to identify fatty replacement in skeletal muscles of late-onset Pompe disease (LOPD) patients. [...]
2021 - 10.3389/fneur.2021.621257
Frontiers in Neurology, Vol. 12 (march 2021)
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8 p, 554.4 KB |
A Simple Score to Identify Super-Responders to Sacubitril/Valsartan in Ambulatory Patients With Heart Failure
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Moliner-Abós, Carles (Institut d'Investigació Biomèdica Sant Pau) ;
Mojón Álvarez, Diana (Hospital del Mar (Barcelona)) ;
Rivas-Lasarte, Mercedes (Institut d'Investigació Biomèdica Sant Pau) ;
Belarte Tornero, Laia Carla (Hospital del Mar (Barcelona)) ;
Pamies Besora, Julia (Institut d'Investigació Biomèdica Sant Pau) ;
Solé-González, Eduard (Hospital del Mar (Barcelona)) ;
Fluvià-Brugues, Paula (Institut d'Investigació Biomèdica Sant Pau) ;
Zegrí-Reiriz, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
López López, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Brossa, Vicens (Institut d'Investigació Biomèdica Sant Pau) ;
Pirla, Maria José (Institut d'Investigació Biomèdica Sant Pau) ;
Mesado, Nuria (Institut d'Investigació Biomèdica Sant Pau) ;
Mirabet, Sonia (Institut d'Investigació Biomèdica Sant Pau) ;
Roig, Eulàlia (Institut d'Investigació Biomèdica Sant Pau) ;
Álvarez-García, Jesús (The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai) ;
Universitat Autònoma de Barcelona
Sacubitril/valsartan (SV) promotes cardiac remodeling and improves prognosis in patients with heart failure (HF). However, the response to the drug may vary between patients and its implementation in daily clinical practice has been slower than expected. [...]
2021 - 10.3389/fphys.2021.642117
Frontiers in physiology, Vol. 12 (february 2021)
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9 p, 999.0 KB |
Long-Term Outcomes of Patients With Cocaine Use Disorder : A 18-years Addiction Cohort Study
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Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández-Rubio, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zuluaga Cruz, Andrea Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Papaseit, Esther (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Galan, Sara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Farré Albaladejo, Magí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Objective: Cocaine Use Disorder (CUD) has been associated with multiple complications and premature death. The purpose of the present study was to analyze the relationship between baseline medical comorbidity and long-term medical outcomes (i. [...]
2021 - 10.3389/fphar.2021.625610
Frontiers in Pharmacology, Vol. 12 (february 2021)
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12 p, 700.5 KB |
Osimertinib in advanced EGFR-T790M mutation-positive non-small cell lung cancer patients treated within the Special Use Medication Program in Spain : OSIREX-Spanish Lung Cancer Group
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Provencio, Mariano (Universidad Autónoma de Madrid) ;
Terrasa, Josefa (Hospital Universitari Son Espases. Medical Oncology Department) ;
Garrido, Pilar (IRYCIS Hospital Universitario Ramón y Cajal. Medical Oncology Department) ;
Campelo, Rosario García (Instituto de Investigación Biomédica A Coruña INIBIC) ;
Aparisi, Francisco (Hospital General Universitario de Valencia. Medical Oncology Department Valencia) ;
Diz, Pilar (Complejo Asistencial Universitario de León. Medical Oncology Department León) ;
Aguiar, David (Hospital Universitario de Gran Canaria Dr. Negrín. Medical Oncology Department) ;
García-Giron, Carlos (Hospital Universitario De Burgos. Medical Oncology Department) ;
Hidalgo, Julia (Hospital Lluís Alcanyis. Medical Oncology Department) ;
Aguado, Carlos (Hospital Clínico San Carlos. Medical Oncology Department) ;
González, Jorge García (Hospital Clínico Universitario de Santiago. Medical Oncology Department Santiago de Compostela) ;
Esteban, Emilio (Hospital Universitario Central de Asturias. Medical Oncology Department) ;
Gómez-Aldavarí, Lorenzo (Complejo Hospitalario Universitario de Albacete. Medical Oncology Department) ;
Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Juan, Oscar (Hospital Universitari i Politècnic La Fe. Medical Oncology Department) ;
Chara, Luís Enrique (Hospital Universitario de Guadalajara. Medical Oncology Department) ;
Marti, Juan L. (Hospital General Universitario de Alicante. Medical Oncology Department) ;
Castro, Rafael López (Hospital Clínico Universitario de Valladolid. Medical Oncology Department) ;
Ortega, Ana Laura (Complejo Hospitalario de Jaen. Medical Oncology Department) ;
Moreno, Elia Martínez (Hospital Virgen de la Salud. Medical Oncology Department) ;
Coves, Juan (Hospital Son Llàtzer. Medical Oncology Department) ;
Sánchez Peña, Ana M. (Hospital Universitario de Getafe. Medical Oncology Department) ;
Bosch-Barrera, Joaquim (Catalan Institute of Oncology. Dr. Josep Trueta University Hospital. Department of Oncology) ;
Gastaldo, Amparo Sánchez (Hospital Universitario Virgen del Rocío. Medical Oncology Department) ;
Núñez, Natalia Fernández (Hospital Universitario Lucus Augusti. Medical Oncology Department) ;
del Barco, Edel (Hospital Universitario de Salamanca. Medical Oncology Department) ;
Cobo, Manuel (Hospitales Universitarios Regional y Virgen de la Victoria, IBIMA, Unidad de Gestión Clínica Intercentros de Oncología Médica) ;
Isla, Dolores (Hospital Universitario Lozano Blesa. Medical Oncology Department) ;
Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ;
Navarro, Fátima (Hospital Universitario Príncipe de Asturias. Medical Oncology Department) ;
Calvo, Virginia (Health Research Institute, Hospital Universitario Puerta de Hierro) ;
Universitat Autònoma de Barcelona
AURA study reported 61% objective response rate and progression-free survival of 9. 6 months with osimertinib in patients with EGFR/T790M+ non-small cell lung cancer. Due to lack of real-world data, we proposed this study to describe the experience with osimertinib in Spain. [...]
2021 - 10.1186/s12885-021-07922-5
BMC Cancer, Vol. 21 (march 2021)
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