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12 p, 524.6 KB |
Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells
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Huyveneers, Laura E. P. (University Medical Center Utrecht) ;
Bruns, Anke (University Medical Center Utrecht) ;
Stam, Arjen (University Medical Center Utrecht) ;
Ellerbroek, Pauline (University Medical Center Utrecht) ;
de Jong, Dorien (University Medical Center Utrecht) ;
Nagy, Noémi A. (University Medical Center Utrecht) ;
Gumbs, Stephanie B. H. (University Medical Center Utrecht) ;
Tesselaar, Kiki (University Medical Center Utrecht) ;
Bosman, Kobus (University Medical Center Utrecht) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Hütter, Gero (DKMS CC) ;
Brosens, Lodewijk A. A. (University Medical Center Utrecht) ;
Kwon, Mi (Hospital General Universitario Gregorio Marañón) ;
Diez Martin, Jose (Hospital General Universitario Gregorio Marañón) ;
van der Meer, Jan T. M. (Amsterdam UMC) ;
de Kort, Theun M. (Leiden University Medical Center) ;
Sáez-Cirión, Asier (Université Paris Cité) ;
Schulze zur Wiesch, Julian (UMC Hamburg-Eppendorf) ;
Boelens, Jaap Jan (Memorial Sloan Kettering Cancer Center) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Kuball, Jurgen (University Medical Center Utrecht) ;
Wensing, Annemarie M. J. (University Medical Center Utrecht) ;
Nijhuis, Monique (University Medical Center Utrecht)
Allo-HSCT with CCR5Δ32/Δ32 donor cells is the only curative HIV-1 intervention. We investigated the impact of allo-HSCT on the viral reservoir in PBMCs and post-mortem tissue in two patients. IciS-05 and IciS-11 both received a CCR5Δ32/Δ32 allo-HSCT. [...]
2022 -  10.3390/v14092069
Viruses, Vol. 14 (september 2022)
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17 p, 810.8 KB |
EAES Recommendations for Recovery Plan in Minimally Invasive Surgery Amid COVID-19 Pandemic
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Arezzo, Alberto (Department of Surgical Sciences. University of Torino) ;
Francis, Nader (The Griffin Institute. The Northwick Park Institute for Medical Research. Northwick Park and St Marks Hospital) ;
Mintz, Yoav (Department of Surgery. Hadassah. Hebrew University Medical Center) ;
Adamina, Michel (Faculty of Medicine. University of Basel) ;
Antoniou, Stavros A. (Department of Surgery. Mediterranean Hospital of Cyprus) ;
Bouvy, Nicole (Department of Surgery. Maastricht University Medical Centre) ;
Copaescu, Catalin (Ponderas Academic Hospital Regina Maria (Bucarest, Romania)) ;
de Manzini, Nicolò (General Surgery Clinic. Department of Medical. Surgical and Health Sciences. University of Trieste. University Hospital of Trieste) ;
Di Lorenzo, Nicola (Department of Surgical Sciences. University of Rome "Tor Vergata") ;
Morales-Conde, Salvador (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Müller-Stich, Beat P. (Department of General. Visceral and Transplantation Surgery. Heidelberg University Hospital) ;
Nickel, Felix (Department of General. Visceral and Transplantation Surgery. Heidelberg University Hospital) ;
Popa, Dorin (General Surgery. Linköping University Hospital) ;
Tait, Diana (The Royal Marsden NHS Foundation Trust) ;
Thomas, Cenydd (Department of Radiology. Yeovil District Hospital NHS Foundation Trust) ;
Nimmo, Susan (Department of Anaesthesia. Critical Care and Pain Medicine. Western General Hospital) ;
Paraskevis, Dimitrios (Department of Hygiene. Epidemiology and Medical Statistics. Medical School. National and Kapodistrian University of Athens) ;
Pietrabissa, Andrea (Department of Surgery. Fondazione IRCCS Policlinico San Matteo) ;
Eck, M. ;
Letić, Emina ;
Preda, Silviu Daniel ;
Tsai, Alice ;
Malanowska, Ewelina ;
Lesko, Dusan ;
Majewski, Wlodzimierz ;
Baldari, Ludovica ;
Morelli, Luca ;
Shamiyeh, Andreas ;
Faria, Gil ;
Carrano, Francesco Maria ;
Mysliwiec, Piotr ;
Ahlberg, Gunnar ;
Cassinotti, Elisa ;
Delibegović, Samir ;
Martinek, Lubomír ;
Yiannakopoulou, Eugenia ;
Gorter-Stam, Marguerite ;
Hanna, George ;
Fuchs, Hans ;
Bjelovic, Miloš ;
Markar, Sheraz ;
Yan, Philip Wai ;
Chiu, Bang ;
Ecom, Bang Wool ;
Kim, Young-Woo ;
Balaguè Ponz, Carmen (Institut d'Investigació Biomèdica Sant Pau) ;
Schijven, Marlies ;
Boni, Luigi ;
Carus, Thomas ;
Theodoropoulos, George ;
Forgione, Antonello ;
Milone, Marco ;
Petz, Luisa Wanda Rita ;
Andrejevic, Predag ;
Ignjatovic, Dejan ;
Arulampalam, Thanjakumar ;
Campbell, Kenneth ;
Chand, Manish ;
Coleman, Mark ;
Kontovounisios, Christos ;
Sagiv, Chen ;
Ficuciello, Fanny ;
Marconi, Stefania ;
Mascagni, Pietro (IHU-Strasbourg. Institute of Image-Guided Surgery) ;
Nakajima, Kiyokazu ;
Sánchez Margallo, Francisco Miguel ;
Horeman, Tim ;
Mylonas, George ;
Valdastri, Pietro
Background: COVID-19 pandemic presented an unexpected challenge for the surgical community in general and Minimally Invasive Surgery (MIS) specialists in particular. This document aims to summarize recent evidence and experts' opinion and formulate recommendations to guide the surgical community on how to best organize the recovery plan for surgical activity across different sub-specialities after the COVID-19 pandemic. [...]
2021 - 10.1007/s00464-020-08131-0
Surgical endoscopy, Vol. 35 Núm. 1 (january 2021) , p. 1-17
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13 p, 4.7 MB |
Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis
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Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Rogers, R. B. (Department of Medicine. University of Cambridge. Cambridge Biomedical Campus) ;
Roy, A. (Department of Paediatrics. University of Oxford) ;
Schneider, P. (Princess Maxima Center for Pediatric Oncology) ;
Bardini, Michela (Università degli Studi di Milano-Bicocca) ;
Ballerini, Paola (Pediatric Hematology. A. Trousseau Hospital) ;
Cazzaniga, Giovanni (Centro Ricerca Tettamanti. Department of Pediatrics. University of Milano Bicocca. Fondazione MBBM) ;
Moreno, T. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ;
Revilla, C. (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ;
Gut, Marta (Universitat Pompeu Fabra) ;
Valsecchi, M. G. (Interfant Trial Data Center. University of Milano-Bicocca) ;
Roberts, I. (MRC Molecular Haematology Unit. MRC Weatherall Institute of Molecular Medicine. University of Oxford) ;
Pieters, R. (Princess Maxima Center for Pediatric Oncology) ;
De Lorenzo, P. (Interfant Trial Data Center. University of Milano-Bicocca) ;
Varela, Ignacio (Instituto de Biomedicina y Biotecnología de Cantabria. Universidad de Cantabria-CSIC) ;
Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Stam, R. W. (Princess Maxima Center for Pediatric Oncology) ;
Universitat Autònoma de Barcelona
Bcell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1 (MLL-AF4) infant B-cell acute lymphoblastic leukemia remains difficult to model, and the pathogenic contribution in cancer of the reciprocal fusions resulting from derivative translocated-chromosomes remains obscure. [...]
2019 - 10.3324/haematol.2018.206375
Haematologica, Vol. 104 Núm. 6 (2019) , p. 1176-1188
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Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency
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Muñoz López, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Romero Moya, Damià (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Prieto, Cristina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ramos Mejía, Verónica (Centro Pfizer - Universidad de Granada - Junta de Andalucía de Genómica e Investigación Oncológica) ;
Agraz-Doblás, Antonio (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Varela, Ignacio (Instituto de Biomedicina y Biotecnología de Cantabria) ;
Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Palau de Miguel, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Carvajal Vergara, Xonia (Universidad de Navarra. Centro de Investigación Médica Aplicada) ;
Giorgetti, Alessandra (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ford, Anthony (Institute of Cancer Research (London, Gran Bretanya)) ;
Lako, Majlinda (Newcastle University. Institute of Genetic Medicine) ;
Granada, Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ruiz Xivillé, Neus (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodríguez Perales, Sandra (Centro Nacional de Investigaciones Oncológicas) ;
Torres Ruíz, Raúl (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Stam, Ronald W. (Erasmus University Medical Center (Rotterdam, Holanda)) ;
Fuster, José Luis (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Fraga, Mario F.. (Instituto Universitario de Oncología del Principado de Asturias (Oviedo)) ;
Nakanishi, Mahito (National Institute of Advanced Industrial Science and Technology (Tsukuba, Japó)) ;
Cazzaniga, Giovanni (Università degli Studi di Milano-Bicocca) ;
Bardini, Michela (Università degli Studi di Milano-Bicocca) ;
Cobo, Isabel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Fernández Bayón, Gustavo (Instituto Universitario de Oncología del Principado de Asturias (Oviedo)) ;
Fernández, Agustín F. (Instituto Universitario de Oncología del Principado de Asturias (Oviedo)) ;
Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Menéndez Bujan, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Induced pluripotent stem cells (iPSCs) are a powerful tool for disease modeling. They are routinely generated from healthy donors and patients from multiple cell types at different developmental stages. [...]
2016 - 10.1016/j.stemcr.2016.08.013
Stem cell reports, Vol. 7 Núm. 4 (October 2016)
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