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Depósito Digital de Documentos de la UAB Encontrados 5 registros  La búsqueda tardó 0.00 segundos. 
1.
13 p, 1.1 MB Immunotherapy for people with clinically isolated syndrome or relapsing-remitting multiple sclerosis : treatment response by demographic, clinical, and biomarker subgroups (PROMISE)-a systematic review protocol / Lehnert, Thomas (University Medical Center Hamburg-Eppendorf) ; Röver, Christian (University Medical Center Göttingen) ; Köpke, Sascha (University of Cologne) ; Río, Jordi (Hospital Universitari Vall d'Hebron) ; Chard, Declan (University College London Hospitals) ; Fittipaldo, Andrea V. (Istituto Ricerche Farmacologiche "Mario Negri" IRCCS) ; Friede, Tim (University Medical Center Göttingen) ; Heesen, Christoph (University Medical Center Hamburg-Eppendorf) ; Rahn, Anne C. (University of Lübeck) ; Universitat Autònoma de Barcelona
Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system with an increasing worldwide prevalence. Since 1993, more than 15 disease-modifying immunotherapies (DMTs) have been licenced and have shown moderate efficacy in clinical trials. [...]
2022 - 10.1186/s13643-022-01997-2
Systematic Reviews, Vol. 11 (july 2022)  
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2.
11 p, 844.8 KB Relationship between paramagnetic rim lesions and slowly expanding lesions in multiple sclerosis / Calvi, Alberto (University College London) ; Clarke, Margareta A. (Hospital Universitari Vall d'Hebron) ; Prados Carrasco, Ferran (University College London) ; Chard, Declan (University College London) ; Ciccarelli, Olga (University College London) ; Alberich, Manel (Hospital Universitari Vall d'Hebron) ; Pareto, Deborah (Hospital Universitari Vall d'Hebron) ; Rodríguez Barranco, Marta (Hospital Universitari Vall d'Hebron) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ; Tur, Carmen (Hospital Universitari Vall d'Hebron) ; Rovira, Alex (Hospital Universitari Vall d'Hebron) ; Barkhof, Frederik (University College London) ; Universitat Autònoma de Barcelona
Magnetic resonance imaging (MRI) markers for chronic active lesions in MS include slowly expanding lesions (SELs) and paramagnetic rim lesions (PRLs). To identify the relationship between SELs and PRLs in MS, and their association with disability. [...]
2022 - 10.1177/13524585221141964
Multiple sclerosis, Vol. 29 (december 2022) , p. 352-362  
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3.
5 p, 792.2 KB The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease / Geraldes, Ruth (Nuffield Department of Clinical Neurosciences) ; Juryńczyk, Maciej (Nuffield Department of Clinical Neurosciences) ; dos Passos, Giordani Rodrigues (Nuffield Department of Clinical Neurosciences) ; Pichler, Alexander (Medical University of Graz. Department of Neurology) ; Chung, Karen (University College London Institute of Neurology) ; Hagens, Marloes (Vrije Universiteit Amsterdam. Department of Neurology) ; Ruggieri, Serena (San Camillo Forlanini Hospital) ; Auger, Cristina (Hospital Universitari Vall d'Hebron) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ; Enzinger, Christian (Medical University of Graz. Department of Neurology) ; Chard, Declan (University College London. Institute of Neurology) ; Barkhof, Frederik (Vrije Universiteit Amsterdam. Department of Radiology and Nuclear Medicine) ; Gasperini, Claudio (San Camillo Forlanini Hospital) ; Rovira, Alex (Hospital Universitari Vall d'Hebron) ; DeLuca, Gabriele (Nuffield Department of Clinical Neurosciences) ; Palace, Jacqueline (Nuffield Department of Clinical Neurosciences) ; Universitat Autònoma de Barcelona
Differentiating multiple sclerosis (MS) from vascular risk factor (VRF)-small vessel disease (SVD) can be challenging. In order to determine whether or not pontine lesion location is a useful discriminator of MS and VRF-SVD, we classified pontine lesions on brain magnetic resonance imaging (MRI) as central or peripheral in 93 MS cases without VRF, 108 MS patients with VRF and 43 non-MS cases with VRF. [...]
2020 - 10.1177/1352458520943777
Multiple sclerosis, Vol. 27 Núm. 6 (2021) , p. 968-972  
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4.
13 p, 1.2 MB Progression of regional grey matter atrophy in multiple sclerosis / Eshaghi, Arman (University College London. Department of Computer Science) ; Marinescu, Razvan V (University College London. Department of Computer Science) ; Young, Alexandra L. (University College London. Department of Computer Science) ; Firth, Nicholas C. (University College London. Department of Computer Science) ; Prados Carrasco, Ferran (University College London. Department of Medical Physics and Bioengineering) ; Jorge Cardoso, M. (University College London. Department of Medical Physics and Bioengineering) ; Tur, Carmen (University College London. Faculty of Brain Sciences) ; De Angelis, Floriana (University College London. Faculty of Brain Sciences) ; Cawley, Niamh (University College London. Faculty of Brain Sciences) ; Brownlee, Wallace J. (University College London. Faculty of Brain Sciences) ; De Stefano, Nicola (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ; Laura Stromillo, M. (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ; Battaglini, Marco (University of Siena (Itàlia). Department of Medicine, Surgery and Neuroscience) ; Ruggieri, Serena (University of Rome Sapienza. Department of Neurology and Psychiatry) ; Gasperini, Claudio (San Camillo Forlanini Hospital) ; Filippi, Massimo (Vita-Salute San Raffaele University (Milà, Itàlia)) ; Rocca, Maria A. (Vita-Salute San Raffaele University (Milà, Itàlia)) ; Rovira, Alex (Hospital Universitari Vall d'Hebron) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Geurts, Jeroen J. G. (Amsterdam UMC. University Medical Center) ; Vrenken, Hugo (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ; Wottschel, Viktor (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ; Leurs, Cyra E. (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ; Uitdehaag, Bernard (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ; Pirpamer, Lukas (Medical University of Graz (Graz, Àustria)) ; Enzinger, Christian (Medical University of Graz (Graz, Àustria)) ; Ourselin, Sebastien (University College London Hospitals) ; Gandini Wheeler-Kingshott, Claudia A. M (IRCCS Mondino Foundation (Pavia, Itàlia)) ; Chard, Declan (University College London Hospitals) ; Thompson, Alan J. (University College London. Faculty of Brain Sciences) ; Barkhof, Frederik (MS Center Amsterdam. Department of Radiology and Nuclear Medicine) ; Alexander, Daniel C.. (University College London. Department of Computer Science) ; Ciccarelli, Olga (University College London Hospitals) ; Universitat Autònoma de Barcelona
See Stankoff and Louapre (doi:) for a scientific commentary on this article. Grey matter atrophy in multiple sclerosis affects certain areas preferentially. Eshaghi et al. use a data-driven computational model to predict the order in which regions atrophy, and use this sequence to stage patients. [...]
2018 - 10.1093/brain/awy088
Brain, Vol. 141 (may 2018) , p. 1665-1677  
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5.
13 p, 862.2 KB Deep gray matter volume loss drives disability worsening in multiple sclerosis / Eshaghi, Arman (University College London) ; Prados Carrasco, Ferran (University College London Hospitals) ; Brownlee, Wallace J. (University College London) ; Altmann, Daniel R. (London School of Hygiene & Tropical Medicine) ; Tur, Carmen (University College London) ; Cardoso, M. Jorge (University College London) ; De Angelis, Floriana (University College London) ; van de Pavert, Steven H. (University College London) ; Cawley, Niamh (University College London) ; De Stefano, Nicola (University of Siena) ; Stromillo, M. Laura (University of Siena) ; Battaglini, Marco (University of Siena) ; Ruggieri, Serena (University of Rome Sapienza) ; Gasperini, Claudio (San Camillo Forlanini Hospital) ; Filippi, Massimo (Vita-Salute San Raffaele University) ; Rocca, Maria A. (Vita-Salute San Raffaele University) ; Rovira, Alex (Hospital Universitari Vall d'Hebron) ; Sastre-Garriga, Jaume (Hospital Universitari Vall d'Hebron) ; Vrenken, Hugo (VU University Medical Centre) ; Leurs, Cyra E. (Amsterdam UMC. University Medical Center) ; Killestein, Joep (Amsterdam UMC. University Medical Center) ; Pirpamer, Lukas (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Ourselin, Sebastien (University College London Hospitals) ; Wheeler-Kingshott, Claudia A. M. Gandini (C. Mondino National Neurological Institute) ; Chard, Declan (University College London Hospitals) ; Thompson, Alan J. (University College London) ; Alexander, Daniel C.. (University College London) ; Barkhof, Frederik (VU University Medical Centre) ; Ciccarelli, Olga (University College London Hospitals) ; Universitat Autònoma de Barcelona
Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with faster disability accumulation in MS. [...]
2018 - 10.1002/ana.25145
Annals of neurology, Vol. 83, Issue 2 (February 2018) , p. 210-222  
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