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14 p, 1.5 MB |
Effects of Albumin Treatment on Systemic and Portal Hemodynamics and Systemic Inflammation in Patients With Decompensated Cirrhosis
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Fernández, Javier (Hospital Clínic i Provincial de Barcelona) ;
Clària, J (Hospital Clínic i Provincial de Barcelona) ;
Amorós, Alex (Grifols) ;
Aguilar, Ferran (Grifols) ;
Castro, Miriam (Hospital Clínic i Provincial de Barcelona) ;
Casulleras, Mireia (Hospital Clínic i Provincial de Barcelona) ;
Acevedo, Juan (Derriford Hospital) ;
Duran, Marta (Hospital Clínic i Provincial de Barcelona) ;
Nuñez, Laura (Grifols) ;
Costa, Montserrat (Grifols) ;
Torres, Mireia (Grifols) ;
Horrillo, Raquel (Grifols) ;
Ruiz-del-Árbol, Luis (Hospital Universitario Ramón y Cajal (Madrid)) ;
Villanueva, Càndid (Institut d'Investigació Biomèdica Sant Pau) ;
Prado, Veronica (Hospital Clínic i Provincial de Barcelona) ;
Arteaga, Mireya (Hospital Clínic i Provincial de Barcelona) ;
Trebicka, Jonel (University Hospital of Bonn) ;
Angeli, Paolo (University of Padova) ;
Merli, Manuela (Sapienza University of Rome) ;
Alessandria, Carlo (San Giovanni Battista Hospital) ;
Aagaard, Niels Kristian (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Soriano, German (Institut d'Investigació Biomèdica Sant Pau) ;
Durand, Francois (Hopital Beaujon) ;
Gerbes, Alexander L. (LMU Munich) ;
Gustot, Thierry (Erasme Hospital (ULB)) ;
Welzel, Tania M. (Goethe University) ;
Salerno, Francesco (Policlinico IRCCS San Donato) ;
Bañares, Rafael (Hospital General Universitario Gregorio Marañón) ;
Vargas Blasco, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Silva, Anibal (Hospital Clínic i Provincial de Barcelona) ;
Morales Ruiz, Manuel (Hospital Clínic i Provincial de Barcelona) ;
García-Pagán, JC. (Hospital Clínic i Provincial de Barcelona) ;
Pavesi, Marco (Grifols) ;
Jalan, Rajiv (Royal Free Hospital) ;
Bernardi, Mauro (University of Bologna) ;
Moreau, Richard (Université Paris Diderot-Paris 7) ;
Páez, Antonio (Grifols) ;
Arroyo, Vicente (Grifols) ;
Universitat Autònoma de Barcelona
We investigated the effect of albumin treatment (20% solution) on hypoalbuminemia, cardiocirculatory dysfunction, portal hypertension, and systemic inflammation in patients with decompensated cirrhosis with and without bacterial infections. [...]
2019 -  10.1053/j.gastro.2019.03.021
Gastroenterology, Vol. 157 Núm. 1 (july 2019) , p. 149-162
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11 p, 767.6 KB |
Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS
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Trebicka, Jonel (Institut de Bioenginyeria de Catalunya) ;
Gu, Wenyi (Shanghai Jiao Tong University) ;
Ibáñez-Samaniego, Luis (Hospital General Universitario Gregorio Marañón) ;
Hernández-Gea, Virginia (Centro de Investigación Biomédica Red de enfermedades hepáticas y digestivas (CIBERehd)) ;
Pitarch, Carla (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
García López, Elisabet (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
Procopet, Bogdan ("Iuliu Hatieganu" University of Medicine and Pharmacy) ;
Giráldez-Gallego, Álvaro (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Amitrano, Lucio (Ospedale A Cardarelli) ;
Villanueva, Càndid (Institut d'Investigació Biomèdica Sant Pau) ;
Thabut, Dominique (Paris Sorbonne Université) ;
Silva-Junior, Gilberto (Hospital Clínic i Provincial de Barcelona) ;
Martinez, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bureau, Cristophe (University Paul Sabatier of Toulouse) ;
Llop, Elba (Universidad Autónoma de Madrid) ;
Laleman, Wim (University Hospitals Leuven (Bèlgica)) ;
Palazon, Jose Maria (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Castellote, Jose (Hospital Universitari de Bellvitge) ;
Rodrigues, Susana G. (Centro Hospitalar São João) ;
Gluud, Lise Lotte (University of Copenhagen) ;
Ferreira, Carlos Noronha (Hospital de Santa Maria - Centro Hospitalar Lisboa Norte) ;
Barcelo, Rafael (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cañete Hidalgo, Nuria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez, Manuel (Hospital Universitario Central de Asturias) ;
Ferlitsch, Arnulf (Medical University of Vienna) ;
Mundi Sánchez-Ramade, Jose Luis (Hospital Universitario San Cecilio (Granada)) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Hernandez-Guerra, Manuel (Hospital Universitario de Canarias (La Laguna)) ;
Sassatelli, Romano (Arcispedale Santa Maria Nuova-IRCCS) ;
Dell'Era, Alessandra (University of the Studies of Milan) ;
Senzolo, Marco (University Hospital of Padova (Pàdua, Itàlia)) ;
Abraldes, Juan G. (University of Alberta) ;
Romero-Gómez, Manuel (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Zipprich, Alexander (Martin Luther University Halle-Wittenberg) ;
Casas, Meritxell (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Primignani, Massimo (CRC "A.M.and A.Miglaivacca" Center for Liver Disease) ;
Weiss, Emmanuel (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
Catalina, María-Vega (Hospital General Universitario Gregorio Marañón) ;
Erasmus, Hans Peter (University of Frankfurt) ;
Uschner, Frank Erhard (University of Frankfurt) ;
Schulz, Martin (University of Frankfurt) ;
Brol, Maximilian Joseph (University of Bonn) ;
Praktiknjo, Michael (University of Bonn) ;
Chang, Johannes (University of Bonn) ;
Krag, Aleksander (Odense University Hospital (Dinamarca)) ;
Nevens, Frederik (University Hospitals Leuven (Bèlgica)) ;
Calleja, Jose Luis (Universidad Autónoma de Madrid) ;
Robic, Marie Angèle (University Paul Sabatier of Toulouse) ;
Conejo, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Rudler, Marika (Paris Sorbonne Université) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Guardascione, Maria Anna (Ospedale A Cardarelli) ;
Tantau, Marcel ("Iuliu Hatieganu" University of Medicine and Pharmacy) ;
Bosch, Jaime (Bern University) ;
Torres, Ferran (Hospital Clínic i Provincial de Barcelona) ;
Pavesi, Marco (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
García-Pagán, JC (Centro de Investigación Biomédica Red de enfermedades hepáticas y digestivas (CIBERehd)) ;
Jansen, Christian (University of Bonn) ;
Bañares, Rafael (Universidad Complutense de Madrid) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The relationship between acute-on-chronic liver failure (ACLF) and acute variceal bleeding (AVB) is poorly understood. Specifically, the prevalence and prognosis of ACLF in the context of AVB is unclear, while the role of transjugular intrahepatic portosystemic shunt (TIPS) in the management in patients with ACLF has not been described to date. [...]
2020 - 10.1016/j.jhep.2020.04.024
Journal of Hepatology, Vol. 73 Núm. 5 (november 2020) , p. 1082-1091
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3.
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14 p, 1.0 MB |
The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology
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Trebicka, Jonel (JW Goethe University Hospital) ;
Fernández, Javier (Hospital Clínic i Provincial de Barcelona) ;
Papp, Maria (University of Debrecen) ;
Caraceni, Paolo (University of Bologna) ;
Laleman, Wim (University of Leuven) ;
Gambino, Carmine (University of Padova) ;
Giovo, Ilaria (University of Torino) ;
Uschner, Frank Erhard (JW Goethe University Hospital) ;
Jiménez, Cesar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mookerjee, Rajeshwar Prosad (UCL Royal Free Hospital) ;
Gustot, Thierry (Universite Libre de Bruxelles) ;
Albillos, Agustín (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Bañares, Rafael (Universidad Complutense de Madrid) ;
Janicko, Martin (Pavol Jozef Safarik University in Kosice) ;
Steib, Christian (University Hospital Munich) ;
Reiberger, Thomas (Medical University of Vienna) ;
Acevedo, Juan (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Gatti, Pietro (Internal Medicine PO Ostuni. ASL Brindisi) ;
Bernal, William (King's College Hospital NHS Foundation Trust) ;
Zeuzem, Stefan (JW Goethe University Hospital) ;
Zipprich, Alexander (University Hospital Halle-Wittenberg) ;
Piano, Salvatore (University of Padova) ;
Berg, Thomas (Leipzig University) ;
Bruns, Tony (Aachen University Hospital) ;
Bendtsen, Flemming (Hvidovre University Hospital) ;
Coenraad, Minneke (Leiden University Medical Center) ;
Merli, Manuela (Universitá Sapienza Roma) ;
Stauber, Rudolf (Medical University of Graz) ;
Zoller, Heinz (Medical University of Innsbruck) ;
Presa Ramos, José (CHTMAD Vila Real) ;
Solé, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Soriano, German (Institut d'Investigació Biomèdica Sant Pau) ;
De Gottardi, Andrea (Universita della Svizzera Italiana) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Saliba, Faouzi (AP-HP Hôpital Paul Brousse) ;
Trautwein, Christian (Aachen University Hospital) ;
Özdogan, Osman Cavit (Marmara University) ;
Francque, Sven (University Hospital Antwerp) ;
Ryder, Stephen David (University of Nottingham) ;
Nahon, Pierre (AP-HP. Hôpital Jean Verdier) ;
Romero-Gómez, Manuel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Van Vlierberghe, Hans (Universitair Ziekenhuis Gent) ;
Francoz, Claire (Université de Paris) ;
Manns, Michael (Hannover Medical School) ;
García López, Elisabet (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Tufoni, Manuel (University of Bologna) ;
Amoros, Alex (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pavesi, Marco (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Sanchez, Cristina (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Curto, Anna (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pitarch, Carla (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Putignano, Antonella (Universite Libre de Bruxelles) ;
Moreno, Esau (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Shawcross, Debbie (King's College Hospital NHS Foundation Trust) ;
Aguilar, Ferran (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Clària, J (Hospital Clínic i Provincial de Barcelona) ;
Ponzo, Paola (University of Torino) ;
Jansen, Christian (University Hospital Bonn (Bonn, Alemanya)) ;
Vitalis, Zsuzsanna (University of Debrecen) ;
Zaccherini, Giacomo (University of Bologna) ;
Balogh, Boglarka (University of Debrecen) ;
Vargas Blasco, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montagnese, Sara (University of Padova) ;
Alessandria, Carlo (University of Torino) ;
Bernardi, Mauro (University of Bologna) ;
Ginès, Pere (Hospital Clínic i Provincial de Barcelona) ;
Jalan, Rajiv (UCL Medical School. Royal Free Hospital) ;
Moreau, Richard (Université de Paris) ;
Angeli, Paolo (University of Padova) ;
Arroyo, Vicente (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Maschmeier, Miriam (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Semela, David (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Elkrief, Laure (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Elsharkawy, Ahmed (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Tornai, Tamás (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Tornai, Istvan (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Altorjay, Istvan (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Antognoli, Agnese (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Baldassarre, Maurizio (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Gagliardi, Martina (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Bertoli, Eleonora (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Mareso, Sara (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Brocca, Alessandra (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Campion, Daniela (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Saracco, Giorgio Maria (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rizzo, Martina (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Lehmann, Jennifer (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Pohlmann, Alessandra (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Praktiknjo, Michael (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Schierwagen, Robert (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Solà, Elsa (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Amari, Nesrine (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rodriguez, Miguel (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Nevens, Frederik (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Clemente, Ana (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Jarcuska, Peter (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Gerbes, Alexander L. (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Mandorfer, Mattias (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Welsch, Christoph (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Ciraci, Emanuela (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Patel, Vish (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Ripoll, Cristina (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Herber, Adam (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Horn, Paul (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Danielsen, Karen Vagner (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Gluud, Lise Lotte (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Schaapman, Jelte (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Riggio, Oliviero (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rainer, Florian (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Moritz, Jörg Tobiasch (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Mesquita, Mónica (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Akpata, Osagie (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Lykke Eriksen, Peter (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Samuel, Didier (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Tresson, Sylvie (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Strnad, Pavel (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Amathieu, Roland (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Simón-Talero, Macarena (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Smits, Francois (PREDICT STUDY group of the EASL-CLIF Consortium) ;
van den Ende, Natalie (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Martinez, Javier (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Garcia, Rita (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Markwardt, Daniel (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rupprechter, Harald (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Engelmann, Cornelius (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Universitat Autònoma de Barcelona
Acute decompensation (AD) of cirrhosis is defined as the acute development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination thereof, requiring hospitalization. [...]
2020 - 10.1016/j.jhep.2020.06.013
Journal of Hepatology, Vol. 73 Núm. 4 (october 2020) , p. 842-854
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5 p, 1.9 MB |
Sinusoidal obstruction syndrome after liver transplantation : A multicenter observational study
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Caballero-Marcos, Aránzazu (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Peligros, Isabel (Hospital General Universitario Gregorio Marañón) ;
Pérez-Rojas, Judith (Hospital Universitari i Politècnic La Fe (València)) ;
Campos Varela, Isabel (Hospital Universitari Vall d'Hebron) ;
Colmenero, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Gómez-Bravo, Miguel Ángel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Justo, Iago (Hospital Universitario 12 de Octubre (Madrid)) ;
Otero, Alejandra (Complejo Hospitalario Universitario de A Coruña) ;
Molina-Pérez, Esther (Hospital Universitario de Santiago) ;
González-Diéguez, Luisa (Hospital Universitario Central de Asturias) ;
Baliellas, Carme (Institut d'Investigació Biomèdica de Bellvitge) ;
Romero-Cristóbal, Mario (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Aguilera Sancho-Tello, Victoria (Hospital Universitari i Politècnic La Fe (València)) ;
Castells, Lluís (Hospital Universitari Vall d'Hebron) ;
Díaz, Alba (Hospital Clínic i Provincial de Barcelona) ;
Marín-Gómez, Luis Miguel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Loinaz, Carmelo (Hospital Universitario 12 de Octubre (Madrid)) ;
Bañares, Rafael (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Salcedo, Magdalena (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Universitat Autònoma de Barcelona
2022 - 10.1002/lt.26452
Liver Transplantation, Vol. 28 (april 2022) , p. 1257-1261
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11 p, 477.7 KB |
Metabolic-associated fatty liver disease : From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH)
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Gallego-Durán, Rocío (SeLiver Group. Instituto de Biomedicina de Sevilla. Consejo Superior de Investigaciones Científicas (Espanya). Universidad de Sevilla) ;
Albillos, Agustín (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Ampuero, Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Arechederra, María (Instituto de Investigación Sanitaria de Navarra) ;
Bañares, Rafael (Universidad Complutense de Madrid. Departamento de Medicina) ;
Blas-García, Ana (Universidad de Valencia. Departamento de Fisiología. Facultad de Medicina) ;
Berná, Genoveva (Universidad Pablo de Olavide. Universidad de Sevilla. Consejo Superior de Investigaciones Científicas (Espanya)) ;
Caparrós, Esther (Instituto de Investigación Sanitaria y Biomédica de Alicante. Hospital General de Alicante) ;
Delgado, Teresa C. (Laboratorio de Enfermedades Hepáticas. Centro de Investigación Cooperativa en Biociencias. Alianza Vasca de Investigación y Tecnología) ;
Falcón-Pérez, Juan Manuel (Ikerbasque Fundación Vasca para las Ciencias) ;
Francés, Rubén (Instituto de Investigación Sanitaria y Biomédica de Alicante. Hospital General de Alicante) ;
Fernández-Barrena, Maite G. (Instituto de Investigación Sanitaria de Navarra) ;
Graupera, Isabel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Iruzubieta, Paula (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Nevzorova, Yulia A. (University Hospital RWTH. Department of Internal Medicine III) ;
Nogueiras, Rubén (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Macías, Rocío I.R. (Grupo de Hepatología Experimental y Focalización de Fármacos (HEVEPHARM). Universidad de Salamanca. Instituto de Investigación Biomédica de Salamanca) ;
Martín, Franz (Universidad Pablo de Olavide. Universidad de Sevilla. Consejo Superior de Investigaciones Científicas (Espanya)) ;
Sabio, Guadalupe (Centro Nacional de Investigaciones Cardiovasculares. Fisiopatología miocárdica) ;
Soriano, German (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vaquero, Javier (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Cubero, Francisco Javoer (Universidad Complutense de Madrid. Departamento de Inmunología, Oftalmología y Otorrinolaringología) ;
Gracia-Sancho, Jordi (Department of Visceral Surgery and Medicine. Inselspital. Bern University Hospital. University of Bern)
This is a meeting report of the 3rd Translational Hepatology Meeting held in Alicante, Spain, in October 2021. The meeting, which was organized by the Spanish Association for the Study of the Liver (AEEH), provided an update on the recent advances in the field of basic and translational hepatology, with a particular focus on the molecular and cellular mechanisms and therapeutic targets involved in metabolic-associated fatty liver disease (MAFLD), metabolic-associated steatohepatitis (MASH), cirrhosis and end-stage hepatocellular carcinoma (HCC).
2022 - 10.1016/j.gastrohep.2022.02.005
Gastroenterologia y Hepatologia, Vol. 45 Núm. 9 (november 2022) , p. 724-734
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18 p, 1.3 MB |
Non-Alcoholic Fatty Liver Disease in Patients with Polycystic Ovary Syndrome : A Systematic Review, Meta-Analysis, and Meta-Regression
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Manzano-Nuñez, Ramiro (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Santana-Dominguez, Marta (Hospital Clínic i Provincial de Barcelona) ;
Rivera-Esteban, Jesús (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Sabiote, Clara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sena, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bañares, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Tacke, Frank (Charité - Universitätsmedizin Berlin) ;
Pericàs, Juan M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
Background: The metabolic effects of polycystic ovary syndrome (PCOS) may increase the risk of non-alcoholic fatty liver disease (NAFLD). However, the burden of NAFLD in PCOS has not been unequivocally defined. [...]
2023 - 10.3390/jcm12030856
Journal of clinical medicine, Vol. 12 (january 2023)
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12 p, 780.3 KB |
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
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Trebicka, Jonel (Department of Internal Medicine I. Goethe University Frankfurt) ;
Fernández, Javier (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Papp, Maria (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Caraceni, Paolo (University of Bologna) ;
Laleman, Wim (University of Leuven) ;
Gambino, Carmine (University of Padova) ;
Giovo, Ilaria (A.O.U. Città della Salute e della Scienza Torino) ;
Uschner, Frank Erhard (Department of Internal Medicine I. Goethe University Frankfurt) ;
Jansen, Christian (Department of Internal Medicine I. University Hospital Bonn) ;
Jimenez, Cesar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mookerjee, Rajeshwar Prosad (UCL Medical School. Royal Free Hospital) ;
Gustot, Thierry (C.U.B. Erasme) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Bañares, Rafael (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Jarcuska, Peter (Pavol Jozef Safarik University in Kosice) ;
Steib, Christian (Department of Medicine II. Liver Centre Munich. University Hospital. LMU) ;
Reiberger, Thomas (Medical University of Vienna) ;
Acevedo, Juan (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Gatti, Pietro (Internal Medicine PO Ostuni) ;
Shawcross, Debbie (King's College Hospital NHS Foundation Trust) ;
Zeuzem, Stefan (Department of Internal Medicine I. Goethe University Frankfurt) ;
Zipprich, Alexander (University Hospital Halle-Wittenberg) ;
Piano, Salvatore (University of Padova) ;
Berg, Thomas (Division of Hepatology. Department of Medicine II. Leipzig University. Medical Center) ;
Bruns, Tony (Aachen University Hospital) ;
Danielsen, Karen Vagner (University of Copenhagen) ;
Coenraad, Minneke (Leiden University Medical Center) ;
Merli, Manuela (Universitá Sapienza Roma) ;
Stauber, Rudolf (Medical University of Graz) ;
Zoller, Heinz (Medical University of Innsbruck) ;
Presa Ramos, José (CHTMAD Vila Real-Blueclinical) ;
Solé, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Soriano, German (Institut d'Investigació Biomèdica Sant Pau) ;
De Gottardi, Andrea (University Clinic of Visceral Surgery and Medicine-Inselspital. Bern and Ente Ospedaliero Cantonale. Universita della Svizzera Italiana) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Saliba, Faouzi (AP-HP Hôpital Paul Brousse. Centre Hépato-Biliaire. Universite Paris Saclay. INSERM Unit 1193) ;
Trautwein, Christian (Aachen University Hospital) ;
Kani, Haluk Tarik (Marmara University) ;
Francque, Sven (University Hospital Antwerp) ;
Ryder, Stephen David (NIHR Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham) ;
Nahon, Pierre (Inserm. UMR-1162. "Génomique fonctionnelle des tumeurs solides") ;
Romero-Gomez, Manuel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Van Vlierberghe, Hans (Universitair Ziekenhuis Gent) ;
Francoz, Claire (Inserm. Université de Paris. Centre de Recherche sur L'Inflammation) ;
Manns, Michael (Hannover Medical School) ;
Garcia-Lopez, Elisabet (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Tufoni, Manuel (University of Bologna) ;
Amoros, Alex (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pavesi, Marco (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Sanchez, Cristina (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Praktiknjo, Michael (Department of Internal Medicine I. University Hospital Bonn) ;
Curto, Anna (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pitarch, Carla (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Putignano, Antonella (C.U.B. Erasme) ;
Moreno, Esau (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Bernal, William (King's College Hospital NHS Foundation Trust) ;
Aguilar, Ferran (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Clària, J (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ponzo, Paola (A.O.U. Città della Salute e della Scienza Torino) ;
Vitalis, Zsuzsanna (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Zaccherini, Giacomo (University of Bologna) ;
Balogh, Boglarka (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Gerbes, Alexander L (Department of Medicine II. Liver Centre Munich. University Hospital. LMU) ;
Vargas, Victor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alessandria, Carlo (A.O.U. Città della Salute e della Scienza Torino) ;
Bernardi, Mauro (University of Bologna) ;
Ginès, Pere (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Moreau, Richard (Inserm. Université de Paris. Centre de Recherche sur L'Inflammation) ;
Angeli, Paolo (University of Padova) ;
Jalan, Rajiv (UCL Medical School. Royal Free Hospital) ;
Arroyo, Vicente (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Maschmeier, Miriam (Munster University Hospital) ;
Semela, David (University of Basel-St Gall Cantonal Hospital) ;
Elkrief, Laure (Hôpitaux Universitaires de Genève) ;
Elsharkawy, Ahmed (University of Birmingham) ;
Tornai, Tamas (University of Birmingham) ;
Tornai, Istvan (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Altorjay, Istvan (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Antognoli, Agnese (University of Bologna) ;
Baldassarre, Maurizio (University of Bologna) ;
Gagliardi, Martina (University of Bologna) ;
Bertoli, Eleonora (University of Padova) ;
Mareso, Sara (University of Padova) ;
Brocca, Alessandra (University of Padova) ;
Campion, Daniela (A.O.U. Città della Salute e della Scienza Torino) ;
Saracco, Giorgio Maria (A.O.U. Città della Salute e della Scienza Torino) ;
Rizzo, Martina (A.O.U. Città della Salute e della Scienza Torino) ;
Lehmann, Jennifer (University Hospital Bonn (Bonn, Alemanya)) ;
Pohlmann, Alessandra (University Hospital Bonn (Bonn, Alemanya)) ;
Brol, Maximilian Joseph (University Hospital Bonn (Bonn, Alemanya)) ;
Chang, Johannes (University Hospital Bonn (Bonn, Alemanya)) ;
Schierwagen, Robert (Department of Internal Medicine I. Goethe University Frankfurt) ;
Solà, Elsa (Hospital Clínic i Provincial de Barcelona) ;
Amari, Nesrine (C.U.B. Erasme) ;
Rodriguez, Miguel (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Nevens, Frederik (Department of Gastroenterology and Hepatology. Section of Liver and Biliopancreatic disorders. University of Leuven) ;
Clemente, Ana (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Janicko, Martin (Pavol Jozef Safarik University in Kosice) ;
Markwardt, Daniel (Department of Medicine II. Liver Centre Munich. University Hospital. LMU) ;
Mandorfer, Mattias (Medical University of Vienna) ;
Welsch, Christoph (Department of Internal Medicine I. Goethe University Frankfurt) ;
Welzel, Tanja M. (Department of Internal Medicine I. Goethe University Frankfurt) ;
Ciraci, Emanuela (Internal Medicine PO Ostuni) ;
Patel, Vish (King's College Hospital NHS Foundation Trust) ;
Ripoll, Cristina (University Hospital Halle-Wittenberg) ;
Herber, Aadam (Division of Hepatology. Department of Medicine II. Leipzig University. Medical Center) ;
Horn, Paul (Jena University Hospital (Alemanya)) ;
Bendtsen, Flemming (Gastrounit. Medical Section. Hvidovre Hospital and Department of Clinical Medicine. University of Copenhagen) ;
Gluud, Lise Lotte (Gastrounit. Medical Section. Hvidovre Hospital and Department of Clinical Medicine. University of Copenhagen) ;
Schaapman, Jelte (Leiden University Medical Center) ;
Riggio, Oliviero (Universitá Sapienza Roma) ;
Rainer, Florian (Medical University of Graz) ;
Moritz, Jörg Tobiasch (Medical University of Innsbruck) ;
Mesquita, M. (CHTMAD Vila Real-Blueclinical) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Akpata, Osagie (UCL Medical School. Royal Free Hospital) ;
Aamann, Luise (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Samuel, Didier (AP-HP Hôpital Paul Brousse. Centre Hépato-Biliaire. Universite Paris Saclay. INSERM Unit 1193) ;
Tresson, Sylvie (AP-HP Hôpital Paul Brousse. Centre Hépato-Biliaire. Universite Paris Saclay. INSERM Unit 1193) ;
Strnad, Pavel (Aachen University Hospital) ;
Amathieu, Roland (Inserm. UMR-1162. "Génomique fonctionnelle des tumeurs solides") ;
Simón-Talero, Macarena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Smits, Francois (C.U.B. Erasme) ;
van den Ende, Natalie (Department of Gastroenterology and Hepatology. Section of Liver and Biliopancreatic disorders. University of Leuven) ;
Martinez, Javier (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Garcia, Rita (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Rupprechter, Harald (Medical University of Vienna) ;
Engelmann, Cornelius (Division of Hepatology. Department of Medicine II. Leipzig University. Medical Center) ;
Özdogan, Osman Cavit (Marmara University) ;
Universitat Autònoma de Barcelona
Background & Aims: Acute decompensation (AD) of cirrhosis may present without acute-on-chronic liver failure (ACLF) (AD-No ACLF), or with ACLF (AD-ACLF), defined by organ failure(s). Herein, we aimed to analyze and characterize the precipitants leading to both of these AD phenotypes. [...]
2021 - 10.1016/j.jhep.2020.11.019
Journal of Hepatology, Vol. 74 Núm. 5 (may 2021) , p. 1097-1108
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6 p, 292.0 KB |
Serum miR-181b-5p predicts ascites onset in patients with compensated cirrhosis
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Garcia Garcia de Paredes, Ana (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Villanueva, Càndid (Institut d'Investigació Biomèdica Sant Pau) ;
Blanco, Carolina (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Manicardi, Nicolo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Garcia-Pagan, Juan Carlos (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Calleja, Jose Luis (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Aracil, Carlos (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Morillas Cunill, Rosa Ma (Universitat Autònoma de Barcelona) ;
Poca Sans, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Peñas, Beatriz (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Augustin Recio, Salvador (Hospital Universitari Vall d'Hebron) ;
Abraldes, Juan G. (University of Alberta) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Royo, Félix (Exosomes Laboratory. Center for Cooperative Research in Biosciencies (CIC bioGUNE). Basque Research and Technology Alliance (BRTA)) ;
García-Bermejo, Mª Laura (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Falcon-Perez, Juan Manuel (Exosomes Laboratory. Center for Cooperative Research in Biosciencies (CIC bioGUNE). Basque Research and Technology Alliance (BRTA)) ;
Bañares, Rafael (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Bosch, Jaime (Department of Biomedical Research and University Clinic for Visceral Medicine and Surgery. Inselspital) ;
Gracia-Sancho, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Albillos, Agustín (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Universitat Autònoma de Barcelona
Background & Aims: Treatment with non-selective beta-blockers (NSBBs) reduces the risk of ascites, which is the most common decompensating event in cirrhosis. This study aimed to assess the ability of a serum microRNA (miRNA) signature to predict ascites formation and the hemodynamic response to NSBBs in compensated cirrhosis. [...]
2021 - 10.1016/j.jhepr.2021.100368
JHEP Reports, Vol. 3 Núm. 6 (december 2021) , p. 100368
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10 p, 1.1 MB |
Risk of infections in patients with NAFLD and Type 2 Diabetes under treatment with SGLT2 inhibitors and relationship with liver outcomes : A retrospective case-control study
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Bañares, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Manzano-Nuñez, Ramiro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prió, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rivera-Esteban, Jesús (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Camps-Relats, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Villarejo, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz-Ortega, Lourdes (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pons, Mònica (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Ciudin, Andreea (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Salcedo, Maria-Teresa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vargas, Víctor (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Genescà Ferrer, Joan (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Pericàs, Juan M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in developed countries, with its incidence growing parallel to the epidemics of obesity and type 2 diabetes mellitus (T2DM). [...]
2022 - 10.3389/fendo.2022.945626
Frontiers in endocrinology, Vol. 13 (august 2022)
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14 p, 825.2 KB |
The role of liver steatosis as measured with transient elastography and transaminases on hard clinical outcomes in patients with COVID-19
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Campos Varela, Isabel (Hospital Universitari Vall d'Hebron) ;
Villagrasa, Ares (Hospital Universitari Vall d'Hebron) ;
Simon-Talero, Macarena (Hospital Universitari Vall d'Hebron) ;
Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ;
Ventura-Cots, Meritxell (Hospital Universitari Vall d'Hebron) ;
Aguilera-Castro, Lara (Hospital Universitari Vall d'Hebron) ;
Álvarez-López, Patricia (Hospital Universitari Vall d'Hebron) ;
Nordahl, Emilie A. (Hospital Universitari Vall d'Hebron) ;
Anton, Adrian (Hospital Universitari Vall d'Hebron) ;
Bañares, Juan (Hospital Universitari Vall d'Hebron) ;
Barber, Claudia (Hospital Universitari Vall d'Hebron) ;
Barreira-Diaz, Ana (Hospital Universitari Vall d'Hebron) ;
Biagetti, Betina (Hospital Universitari Vall d'Hebron) ;
Camps-Relats, Laura (Hospital Universitari Vall d'Hebron) ;
Ciudin, Andreea (Hospital Universitari Vall d'Hebron) ;
Cocera, Raul (Hospital Universitari Vall d'Hebron) ;
Dopazo, Cristina (Hospital Universitari Vall d'Hebron) ;
Fernandez, Andrea (Hospital Universitari Vall d'Hebron) ;
Jiménez, Cesar (Hospital Universitari Vall d'Hebron) ;
Jiménez, María M. (Hospital Universitari Vall d'Hebron) ;
Jofra, Mariona (Hospital Universitari Vall d'Hebron) ;
Gil, Clara (Hospital Universitari Vall d'Hebron) ;
Gómez Gavara, Concepción (Hospital Universitari Vall d'Hebron) ;
Guanozzi, Danila (Hospital Universitari Vall d'Hebron) ;
Guevara, Jorge A. (Hospital Universitari Vall d'Hebron) ;
Lobo Álvarez, Beatriz (Hospital Universitari Vall d'Hebron) ;
Malagelada Prats, Carolina (Hospital Universitari Vall d'Hebron) ;
Martinez-Camprecios, Joan (Hospital Universitari Vall d'Hebron) ;
Mayorga, Luis (Hospital Universitari Vall d'Hebron) ;
Miret Alomar, Enric (Hospital Universitari Vall d'Hebron) ;
Pando, Elizabeth (Hospital Universitari Vall d'Hebron) ;
Pérez-Lopez, Ana (Hospital Universitari Vall d'Hebron) ;
Pigrau Pastor, Marc (Hospital Universitari Vall d'Hebron) ;
Prió, Alba (Hospital Universitari Vall d'Hebron) ;
Rivera-Esteban, Jesus M. (Hospital Universitari Vall d'Hebron) ;
Romero, Alba (Hospital Universitari Vall d'Hebron) ;
Tasayco, Staphanie (Hospital Universitari Vall d'Hebron) ;
Vidal-Gonzalez, Judit (Hospital Universitari Vall d'Hebron) ;
Vidal, Laura (Hospital Universitari Vall d'Hebron) ;
Minguez, Beatriz (Hospital Universitari Vall d'Hebron) ;
Augustin Recio, Salvador (Hospital Universitari Vall d'Hebron) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Liver injury has been widely described in patients with Coronavirus disease 2019 (COVID-19). We aimed to study the effect of liver biochemistry alterations, previous liver disease, and the value of liver elastography on hard clinical outcomes in COVID-19 patients. [...]
2021 - 10.1177/17562848211016567
Therapeutic Advances in Gastroenterology, Vol. 14 (may 2021)
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