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17 p, 3.5 MB |
The recovery of cognitive and affective deficiencies linked with chronic osteoarthritis pain and implicated pathways by slow-releasing hydrogen sulfide treatment
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Batallé Melgarejo, Gerard (Institut d'Investigació Biomèdica Sant Pau) ;
Bai, Xue (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pouso-Vázquez, Enric (Institut d'Investigació Biomèdica Sant Pau) ;
Roch, Gerard (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Rodríguez, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pol, Olga (Universitat Autònoma de Barcelona. Institut de Neurociències)
Chronic osteoarthritis pain is accompanied by several comorbidities whose treatment has not been completely resolved. The anti-inflammatory, analgesic, and antidepressant effects of slow-releasing hydrogen sulfide (H2S) donors during osteoarthritic pain have been shown, but their actions in the accompanying memory impairment and anxious-like behaviors have not yet been demonstrated. [...]
2021 -  10.3390/antiox10101632
Antioxidants, Vol. 10 Núm. 10 (october 2021) , p. 1632
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21 p, 3.3 MB |
Hydrogen sulfide inhibits inflammatory pain and enhances the analgesic properties of delta opioid receptors
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Porta, Aina (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Rodríguez, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Bai, Xue (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Batallé Melgarejo, Gerard (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Roch, Gerard (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pouso-Vázquez, Enric (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Balboni, Gianfranco (University of Cagliari. Department of Life and Environmental Sciences) ;
Pol, Olga (Universitat Autònoma de Barcelona. Institut de Neurociències)
Chronic inflammatory pain is present in many pathologies and diminishes the patient's quality of life. Moreover, most current treatments have a low efficacy and significant side effects. Recent studies demonstrate the analgesic properties of slow-releasing hydrogen sulfide (HS) donors in animals with osteoarthritis or neuropathic pain, but their effects in inflammatory pain and related pathways are not completely understood. [...]
2021 - 10.3390/antiox10121977
Antioxidants, Vol. 10 Núm. 12 (december 2021) , p. 1977
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19 p, 2.8 MB |
The Beneficial Effects of Heme Oxygenase 1 and Hydrogen Sulfide Activation in the Management of Neuropathic Pain, Anxiety- and Depressive-like Effects of Paclitaxel in Mice
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Roch, Gerard (Institut d'Investigació Biomèdica Sant Pau) ;
Batallé Melgarejo, Gerard (Institut d'Investigació Biomèdica Sant Pau) ;
Bai, Xue (Institut d'Investigació Biomèdica Sant Pau) ;
Pouso-Vázquez, Enric (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Rodríguez, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pol, Olga (Universitat Autònoma de Barcelona. Institut de Neurociències)
Chemotherapy-induced peripheral neuropathy constitutes an unresolved clinical problem that severely decreases the quality of the patient's life. It is characterized by somatosensory alterations, including chronic pain, and a high risk of suffering mental disorders such as depression and anxiety. [...]
2022 - 10.3390/antiox11010122
Antioxidants, Vol. 11 (january 2022)
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11 p, 1.4 MB |
Urelumab alone or in combination with rituximab in patients with relapsed or refractory B-cell lymphoma
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Timmerman, John (UCLA Medical Center) ;
Herbaux, Charles (Centre Hospitalier Régional Universitaire de Lille) ;
Ribrag, Vincent (Institut Gustave Roussy (Villejuif, França)) ;
Zelenetz, Andrew D. (Memorial Sloan Kettering Cancer Center) ;
Houot, Roch (Unité dʼInvestigation Clinique) ;
Neelapu, Sattva S. (The University of Texas MD Anderson Cancer Center) ;
Logan, Theodore (Indiana University) ;
Lossos, Izidore S. (Sylvester Comprehensive Cancer Center) ;
Urba, Walter (Providence Cancer Center) ;
Salles, Gilles (Université de Lyon) ;
Ramchandren, Radhakrishnan (Karmanos Cancer Institute) ;
Jacobson, Caron (Harvard Medical School) ;
Godwin, John (Providence Cancer Center) ;
Carpio Segura, Cecilia del Carmen (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Lathers, Deanne (Bristol-Myers Squibb) ;
Liu, Yali (Bristol-Myers Squibb) ;
Neely, Jaclyn (Bristol-Myers Squibb) ;
Suryawanshi, Satyendra (Bristol-Myers Squibb) ;
Koguchi, Yoshinobu (Providence Cancer Center) ;
Levy, Ronald (Stanford University School of Medicine)
Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity in preclinical models, and may enhance cytotoxic activity of rituximab. [...]
2020 - 10.1002/ajh.25757
American Journal of Hematology, Vol. 95 (february 2020) , p. 510-520
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4 p, 96.8 KB |
Realising the European network of biodosimetry : RENEB-status quo
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Kulka, U. (Bundesamt für Strahlenschutz (Alemanya)) ;
Ainsbury, Elizabeth Ann (Public Health England (Chilton, Regne Unit)) ;
Atkinson, M. (Helmholtz Zentrum München) ;
Barnard, S. (Public Health England (Chilton, Regne Unit)) ;
Smith, R. (Public Health England (Chilton, Regne Unit)) ;
Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Barrios, Leonardo (Universitat Autònoma de Barcelona) ;
Bassinet, C. (Institut de Radioprotection et de Sûreté Nucléaire) ;
Beinke, C. (Universität Ulm. Bundeswehr Institut für Radiobiologie) ;
Cucu, A. (Institutul National de Sănătate Publică (Bucarest, Romania)) ;
Darroudi, F. (Leids Universitair Medisch Centrum) ;
Fattibene, P. (Istituto Superiore di Sanità (Roma, Itàlia)) ;
Bortolin, E. (Istituto Superiore di Sanità (Roma, Itàlia)) ;
Monaca, S. Della (Istituto Superiore di Sanità (Roma, Itàlia)) ;
Monteiro Gil, Octávia (Universidade de Lisboa. Instituto Superior Técnico) ;
Gregoire, Eric (Institut de Radioprotection et de Sûreté Nucléaire) ;
Hadjidekova, Valeria B. (National Centre of Radiobiology and Radiation Protection (Sofia, Bulgària)) ;
Haghdoost, Siamak (Stockholms universitet) ;
Hatzi, Vasiliki I. (National Centre for Scientific Research Demokritos (Atenes, Grècia)) ;
Hempel, William M. (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Herranz, R. (Hospital General Universitario Gregorio Marañón) ;
Jaworska, A. (Norwegian: Statens strålevern) ;
Lindholm, C. (Radiation and Nuclear Safety Authority (Hèlsinki, Finlàndia)) ;
Lumniczky, Katalin (National Research Institute for Radiobiology and Radiohygiene (Budapest, Hongria)) ;
M'kacher, R. (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Mörtl, S. (Helmholtz Zentrum München) ;
Montoro, A. (Hospital Universitari i Politècnic La Fe (València)) ;
Moquet, J. (Public Health England (Chilton, Regne Unit)) ;
Moreno, M. (Hospital General Universitario Gregorio Marañón) ;
Noditi, M. (Institutul National de Sănătate Publică (Bucarest, Romania)) ;
Ogbazghi, A. (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Oestreicher, U. (Bundesamt für Strahlenschutz) ;
Palitti, F. (Università degli Studi della Tuscia) ;
Pantelias, G. (National Centre for Scientific Research Demokritos (Atenes, Grècia)) ;
Popescu, I. (Institutul National de Sănătate Publică (Bucarest, Romania)) ;
Prieto, M. J. (Hospital General Universitario Gregorio Marañón) ;
Roch-Lefevre, S. (Institut de Radioprotection et de Sûreté Nucléaire) ;
Roessler, U. (Bundesamt für Strahlenschutz) ;
Romm, H. (Bundesamt für Strahlenschutz) ;
Rothkamm, K. (Helmholtz Zentrum München) ;
Sabatier, L. (Commissariat à l'Énergie Atomique et aux Énergies Alternatives (França)) ;
Sebastià, N. (Hospital Universitari i Politècnic La Fe (València)) ;
Sommer, S. (Instytut Chemii i Techniki Jadrowej (Warsaw, Poland)) ;
Terzoudi, G. (National Centre for Scientific Research Demokritos (Atenes, Grècia)) ;
Testa, A. (Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (Roma, Itàlia)) ;
Thierens, H. (Università degli Studi della Tuscia) ;
Trompier, François (Institut de Radioprotection et de Sûreté Nucléaire) ;
Turai, I. (National Research Institute for Radiobiology and Radiohygiene (Budapest, Hongria)) ;
Vandevoorde, C. (Universiteit Gent) ;
Vaz, P. (Universidade de Lisboa. Instituto Superior Técnico) ;
Voisin, Pascale (Institut de Radioprotection et de Sûreté Nucléaire) ;
Vral, A. (Universiteit Gent) ;
Ugletveit, F. (Norwegian: Statens strålevern) ;
Wieser, A. (Helmholtz Zentrum München) ;
Woda, C. (Helmholtz Zentrum München) ;
Wojcik, A. (Stockholms universitet)
Creating a sustainable network in biological and retrospective dosimetry that involves a large number of experienced laboratories throughout the European Union (EU) will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. [...]
2015 - 10.1093/rpd/ncu266
Radiation protection dosimetry, Vol. 164, issue 1-2 (April 2015) , p. 42-45
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10 p, 47.1 KB |
El sida en Cuba
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Rodríguez Roch, Liana (Universidad de La Habana)
Las siglas S. I. D. A. significan síndrome de inmuno deficiencia adquirida. Sida es una definición operativa del estadio extremo de la infección por el VIH (virus de la inmunodeficiencia humana). [...]
Aids is the extreme result of the HIV infection. Statistics show several ways of diffussion of "sida" or Aids through sexual relations, drugs, etc. This things into question the problem of death, sexuality, illness, to be controlled by the National Pragramme to Fight Aids as well as health treatment and education.
1997 - 10.5565/rev/papers/v52n0.1888
Papers : revista de sociologia, N. 52 (1997) , p. 177-186
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