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8 p, 602.5 KB Lactic acidosis associated with metformin in patients with moderate to severe chronic kidney disease : Study protocol for a multicenter population-based case-control study using health databases / Pedrós, Consuelo (Institut d'Investigació Biomèdica de Bellvitge) ; Ávila, Mónica (Institut d'Investigació Biomèdica de Bellvitge) ; Gomez-Lumbreras, Ainhoa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Manríquez, Marcela (Institut d'Investigació Biomèdica de Bellvitge) ; Morros, Rosa. (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Background: The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce. [...]
2019 - 10.1186/s12882-019-1389-8
BMC Nephrology, Vol. 20 Núm. 1 (05 2019)  
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