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Research literature, 1 records found
Research literature 1 records found  
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256 p, 4.4 MB Development of Pichia pastoris for the production of human α-galactosidase A as a model lysosomal enzyme / Barreiro Vázquez, Antonio ; Resina Rodríguez, David, dir. ; Ferrer, Pau ; Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental
L'α-galactosidasa A humana (GLA) pertany a la família d'hidrolases lisosomals involucrades en malalties d'emmagatzemat enzimàtic (MEEs). Les teràpies de reemplaçament enzimàtic (TREs), basades en l'administració de l'enzim disfuncional, són una mesura eficient per alentir l'avanç d'algunes MEEs. [...]
Human α-galactosidase A (GLA) belongs to the family of lysosomal hydrolases involved in lysosomal storage diseases (LSDs). Enzyme replacement therapies (ERTs), based on the administration of the recombinant missing enzyme, are an efficient measure to slow the advance of some LSDs. [...]
[Barcelona] : Universitat Autònoma de Barcelona, 2016  
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