Thirst distress in outpatients with heart failure in a Mediterranean zone of Spain
Eng, Sanna Hagelberg (Linköping University)
Waldréus, Nana (Karolinska University Hospital and Karolinska Institutet (Suècia))
González Fernández, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ehrlin, Jenny (Linköping University)
Díaz, Violeta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Rivas Jiménez, Carmen (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Velayos, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Puertas, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ros, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Martín, Paula (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Lupón, Josep (Instituto de Salud Carlos III)
Bayés-Genís, Antoni (Instituto de Salud Carlos III)
Jaarsma, Tiny (Linköping University)

Fecha:	2021
Resumen:	This study aimed to evaluate psychometric properties of the Spanish version of the Thirst Distress Scale for patients with Heart Failure (TDS-HF) and to describe thirst distress-associated factors in outpatients at a heart failure (HF) clinic in Spain. Thirst is common in patients with HF, but thirst distress has rarely been addressed and may significantly decrease quality of life. A cross-sectional study was performed assessing perceived thirst distress by patients with HF during the preceding 3 days, with the TDS-HF (scores 8 to 40). Univariable and multivariable linear regression analyses were performed to identify variables independently associated with thirst distress. Three-hundred two HF outpatients were included (age 67 ± 12 years, 74% male, HF duration 82 ± 75 months, left ventricular ejection fraction 42 ± 14%). Most patients were on treatment with fluid restriction (99%), sodium restriction (99%), and diuretics (70%). The psychometric evaluation of the Spanish version of the TDS-HF showed satisfactory item-total and inter-item correlations (range from 0. 77 to 0. 85 and 0. 60 to 0. 84, respectively), and internal consistency was 0. 95 (Cronbach's alpha). The majority perceived mild to moderate thirst distress, and 18% perceived it as high or severe. The mean score obtained was 16. 2 ± 9. 3 (median 13, Q1-Q3 8-20). Higher serum urea {beta coefficient 1. 6 [95% confidence interval (CI) 0. 267 to 2. 92], P = 0. 019} and lower potassium [beta coefficient −3. 63 (85% CI −6. 32 to −0. 93), P = 0. 009] remained significantly associated with thirst distress in the multivariable analysis, together with the dose of diuretics [beta coefficient 2. 98 (95% CI 1. 37 to 4. 59), P < 0. 001]. Treatment with angiotensin receptor blocker showed an independent protective effect [beta coefficient −3. 62 (95% CI −6. 89 to −0. 345), P = 0. 03]. The psychometric evaluation of the Spanish version of the TDS-HF showed good psychometric properties. One in five patients experienced severe distress by thirst, but the majority had mild to moderate thirst distress. The dose of diuretics and angiotensin receptor blocker treatment influence thirst distress and could be clinically important targets to relieve thirst distress in patients with HF.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Heart failure ; Thirst ; Thirst distress ; Quality of life ; ARB ; Diuretics
Publicado en:	ESC Heart Failure, Vol. 8 (may 2021) , p. 2492-2501, ISSN 2055-5822

DOI: 10.1002/ehf2.13395
PMID: 33942551

10 p, 537.6 KB

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