Calicivirus Infection in Cats
Hofmann-Lehmann, Regina (University of Zurich. Clinical Laboratory, Department of Clinical Diagnostics and Services)
Hosie, Margaret J. (University of Glasgow Centre for Virus Research)
Hartmann, Katrin (Ludwig Maximilian University of Munich. Clinic of Small Animal Medicine)
Egberink, Herman (University of Utrecht. Department of Biomolecular Health Sciences)
Truyen, Uwe (University of Leipzig. Institute of Animal Hygiene and Veterinary Public Health)
Tasker, Séverine (Linnaeus Veterinary Limited)
Belák, Sándor (Swedish University of Agricultural Sciences (SLU). Department of Biomedical Sciences and Veterinary Public Health)
Boucraut-Baralon, Corine (Scanelis Laboratory)
Frymus, Tadeusz (Warsaw University of Life Sciences. Department of Small Animal Diseases with Clinic)
Lloret Roca, Albert (Universitat Autònoma de Barcelona. Hospital Clínic Veterinari)
Marsilio, Fulvio (Università degli Studi di Teramo. Faculty of Veterinary Medicine)
Pennisi, Maria Grazia (Università di Messina. Dipartimento di Scienze Veterinarie)
Addie, Diane D. (University of Glasgow. School of Veterinary Medicine)
Lutz, Hans (University of Zurich. Department of Clinical Diagnostics and Services)
Thiry, Etienne (Liège University. Veterinary Virology and Animal Viral Diseases)
Radford, Alan D. (University of Liverpool. Institute of Infection, Veterinary and Ecological Sciences)
Möstl, Karin (University of Veterinary Medicine. Institute of Virology)

Data:	2022
Resum:	Feline calicivirus (FCV) is a common pathogen in domestic cats that is highly contagious, resistant to many disinfectants and demonstrates a high genetic variability. FCV infection can lead to serious or even fatal diseases. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from 11 European countries, presents the current knowledge of FCV infection and fills gaps with expert opinions. FCV infections are particularly problematic in multicat environments. FCV-infected cats often show painful erosions in the mouth and mild upper respiratory disease and, particularly in kittens, even fatal pneumonia. However, infection can be associated with chronic gingivostomatitis. Rarely, highly virulent FCV variants can induce severe systemic disease with epizootic spread and high mortality. FCV can best be detected by reverse-transcriptase PCR. However, a negative result does not rule out FCV infection and healthy cats can test positive. All cats should be vaccinated against FCV (core vaccine); however, vaccination protects cats from disease but not from infection. Considering the high variability of FCV, changing to different vaccine strain(s) may be of benefit if disease occurs in fully vaccinated cats. Infection-induced immunity is not life-long and does not protect against all strains; therefore, vaccination of cats that have recovered from caliciviral disease is recommended.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	FCV ; Feline ; Multicat environment ; Genetic variability ; Virulent systemic ; Diagnosis ; Vaccination ; Vaccine strains ; Tenacity ; Treatment
Publicat a:	Viruses, Vol. 14 (april 2022) , ISSN 1999-4915

DOI: 10.3390/v14050937
PMID: 35632680

31 p, 4.3 MB

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