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9 p, 599.8 KB |
Reduced 8-Gray Compared to Standard 12-Gray Total Body Irradiation for Allogeneic Transplantation in First Remission Acute Lymphoblastic Leukemia : A Study of the Acute Leukemia Working Party of the EBMT
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Spyridonidis, Alexandros (University of Patras) ;
Labopin, Myriam (Sorbonne University) ;
Savani, Bipin (Vanderbilt University Medical Center) ;
Giebel, Sebastian (Maria Sklodowska-Curie National Research Institute of Oncology) ;
Bug, Gesine (Department of Medicine II. Goethe-University) ;
Schönland, Stefan (Medical Department V. University Hospital Heidelberg) ;
Kröger, Nicolaus (Department of Stem Cell Transplantation. University Medical Center) ;
Stelljes, Matthias (Department of Hematology/Oncology. University of Muenster) ;
Schroeder, Thomas (Department of Bone Marrow Transplantation. University Hospital) ;
Mcdonald, Andrew (Netcare Pretoria East Hospital) ;
Blau, Igor-Wolfgang (Charité - Universitätsmedizin Berlin) ;
Bornhäuser, Martin (University Hospital. TU Dresden) ;
Rovira, Montse (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bethge, Wolfgang (Department of Hematology & Oncology. University Hospital Tuebingen.) ;
Neubauer, Andreas (Philipps Universitaet Marburg) ;
Ganser, Arnold (Hannover Medical School) ;
Bourhis, Jean Henri (Gustave Roussy Cancer Campus BMT. Department of Hematology) ;
Edinger, Matthias (University Regensburg. Department of Hematology and Oncology) ;
Lioure, Bruno (Hematology. Stem Cell Transplant Unit. ICANS) ;
Wulf, Gerald (University Medicine Goettingen) ;
Schäfer-Eckart, Kerstin (Klinikum Nuernberg. 5. Medizinische Klinik. BMT-Unit) ;
Arat, Mutlu (Demiroglu Bilim Univ. Istanbul Florence Nightingale Hospital) ;
Peric, Zinaida (University Hospital Centre) ;
Schmid, Christoph (Universitatsklinikum Augsburg. Section Stem Cell Transplantation. Augsburg University and Medical Faculty) ;
Bazarbachi, Ali (Bone Marrow Transplantation Program. Department of Internal Medicine. American University of Beirut-Medical Center) ;
Ciceri, Fabio (Ospedale San Raffaele) ;
Nagler, Arnon (Hematology Division. Chaim Sheba Medical Center) ;
Mohty, Mohamad (Sorbonne Université)
In this registry-based study, we compared outcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in adult patients with acute lymphoblastic leukemia (ALL) transplanted in first complete remission (CR-1), following conditioning with total body irradiation (TBI) at a standard 12-Gray or at a lower 8-Gray total dose. [...]
2023 -  10.1097/HS9.0000000000000812
HemaSphere, Vol. 7 Núm. 1 (september 2023) , p. e812
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2.
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12 p, 804.5 KB |
RIC versus MAC UCBT in adults with AML : A report from Eurocord, the ALWP and the CTIWP of the EBMT
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Baron, Frédéric (University of Liege) ;
Ruggeri, Annalisa (Hôpital Saint-Antoine (Paris, França)) ;
Beohou, Eric (Hôpital Saint-Antoine (Paris, França)) ;
Labopin, Myriam (Hôpital Saint-Antoine (Paris, França)) ;
Sanz, Guillermo (Hospital Universitari i Politècnic La Fe (València)) ;
Milpied, Noel (University of Bordeaux) ;
Michallet, Mauricette (Centre Hospitalier de Lyon Sud) ;
Bacigalupo, Andrea (Ospedale San Martino) ;
Blaise, Didier (Aix-Marseille Université) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Socié, Gérard (Hospital Saint-Louis) ;
Cornelissen, Jan J. (Erasmus Medical Center-Daniel den Hoed Cancer Center) ;
Schmid, Christoph (University of Munich) ;
Giebel, Sebastian (Gliwice Branch) ;
Gorin, Norbert-Claude (Hospital Saint Antoine) ;
Esteve, Jordi (Hematology. Hospital Clinic) ;
Ciceri, Fabio (Ospedale San Raffaele) ;
Savani, Bipin N. (Vanderbilt University Medical Center) ;
Mohty, Mohamad (UMRs 938) ;
Gluckman, Eliane (Centre Scientifique de Monaco) ;
Nagler, Arnon (The Chaim Sheba Medical Center) ;
Universitat Autònoma de Barcelona
Nonrelapse mortality (NRM) is the first cause of treatment failure after unrelated cord blood transplantation (UCBT) following myeloablative conditioning (MAC). In the last decade, reduced-intensity conditioning (RIC) regimens have been developed with the aim of reducing NRM and allowing older patients and those with medical comorbidities to benefit from UCBT. [...]
2016 - 10.18632/oncotarget.9599
Oncotarget, Vol. 7 Núm. 28 (2016) , p. 43027-43038
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3.
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10 p, 1.4 MB |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
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Manry, Jérémy ;
Bastard, Paul ;
Gervais, Adrian ;
Le Voyer, Tom ;
Rosain, Jérémie ;
Philippot, Quentin ;
Michailidis, Eleftherios ;
Hoffmann, Hans-Heinrich ;
Eto, Shohei ;
Garcia-Prat, Marina (Hospital Universitari Vall d'Hebron) ;
Bizien, Lucy ;
Parra-Martínez, Alba (Hospital Universitari Vall d'Hebron) ;
Yang, Rui ;
Haljasmägi, Liis ;
Migaud, Mélanie ;
Särekannu, Karita ;
Maslovskaja, Julia ;
de Prost, Nicolas ;
Tandjaoui-Lambiotte, Yacine ;
Luyt, Charles-Edouard ;
Amador-Borrero, Blanca ;
Gaudet, Alexandre ;
Poissy, Julien ;
Morel, Pascal ;
Richard, Pascale ;
Cognasse, Fabrice ;
Troya, Jesús ;
Trouillet-Assant, Sophie ;
Belot, Alexandre ;
Saker, Kahina ;
Garçon, Pierre ;
Rivière, Jacques G.. (Hospital Universitari Vall d'Hebron) ;
Lagier, Jean-Christophe ;
Gentile, Stéphanie ;
Rosen, Lindsey B. ;
Shaw, Elana ;
Morio, Tomohiro ;
Tanaka, Junko ;
Dalmau, David ;
Tharaux, Pierre-Louis ;
Sene, Damien ;
Stepanian, Alain ;
Mégarbane, Bruno ;
Triantafyllia, Vasiliki ;
Fekkar, Arnaud ;
Heath, James R. ;
Franco, Jose Luis ;
Anaya, Juan-Manuel ;
Solé-Violán, Jordi ;
Imberti, Luisa ;
Biondi, Andrea ;
Bonfanti, Paolo ;
Castagnoli, Riccardo ;
Delmonte, Ottavia M. ;
Zhang, Yu ;
Snow, Andrew ;
Holland, Steven M. ;
Biggs, Catherine M. ;
Moncada-Vélez, Marcela ;
Arias, Andrés Augusto ;
Lorenzo, Lazaro ;
Boucherit, Soraya ;
Anglicheau, Dany ;
Planas, Anna Maria ;
Haerynck, Filomeen ;
Duvlis, Sotirija ;
Ozcelik, Tayfun ;
Keles, Sevgi ;
Bousfiha, Ahmed A. ;
El Bakkouri, Jalila ;
Ramirez-Santana, Carolina ;
Paul, Stephane ;
Pan-Hammarström, Qiang ;
Hammarström, Lennart ;
Dupont, Annabelle ;
Kurolap, Alina ;
Metz, Christine N. ;
Aiuti, Alessandro ;
Casari, Giorgio ;
Lampasona, Vito ;
Ciceri, Fabio ;
Barreiros, Lucila A. ;
Domínguez-Garrido, Elena ;
Vidigal, Mateus ;
Zatz, Mayana ;
van de Beek, Diederik ;
Sahanic, Sabina ;
Tancevski, Ivan ;
Stepanovskyy, Yurii ;
Boyarchuk, Oksana ;
Nukui, Yoko ;
Tsumura, Miyuki ;
Vidaur, Loreto ;
Tangye, Stuart G. ;
Burrel, Sonia ;
Duffy, Darragh ;
Quintana-Murci, Lluis ;
Klocperk, Adam ;
Kann, Nelli Y. ;
Shcherbina, Anna ;
Lau, Yu-Lung ;
Leung, Daniel ;
Coulongeat, Matthieu ;
Marlet, Julien ;
Koning, Rutger ;
Reyes, Luis Felipe ;
Chauvineau-Grenier, Angélique ;
Venet, Fabienne ;
Monneret, Guillaume ;
Nussenzweig, Michel C. ;
Arrestier, Romain ;
Boudhabhay, Idris ;
Baris-Feldman, Hagit ;
Hagin, David ;
Wauters, Joost ;
Meyts, Isabelle ;
Dyer, Adam H. ;
Kennelly, Sean P. ;
Bourke, Nollaig M. ;
Halwani, Rabih ;
Sharif-Askari, Fatemeh Saheb ;
Dorgham, Karim ;
Sallette, Jérôme ;
Sedkaoui, Souad Mehlal ;
AlKhater, Suzan ;
Rigo Bonnin, Raül (Institut d'Investigació Biomèdica de Bellvitge) ;
Morandeira, Francisco ;
Roussel, Lucie ;
Vinh, Donald C. ;
Erikstrup, Christian ;
Condino-Neto, Antonio ;
Prando, Carolina ;
Bondarenko, Anastasiia ;
Spaan, András N. ;
Gilardin, Laurent ;
Fellay, Jacques ;
Lyonnet, Stanislas ;
Bilguvar, Kaya ;
Lifton, Richard P. ;
Mane, Shrikant ;
Anderson, Mark S. ;
Boisson, Bertrand ;
Béziat, Vivien ;
Zhang, Shen-Ying ;
Andreakos, Evangelos ;
Hermine, Olivier ;
Pujol, Aurora 1968- (Institut d'Investigació Biomèdica de Bellvitge) ;
Peterson, Pärt ;
Mogensen, Trine H. ;
Rowen, Lee ;
Mond, James ;
Debette, Stéphanie ;
De Lamballerie, Xavier ;
Burdet, Charles ;
Bouadma, Lila ;
Zins, Marie ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron) ;
Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron) ;
Gorochov, Guy ;
Solanich, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ;
Susen, Sophie ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Raoult, Didier ;
Vasse, Marc ;
Gregersen, Peter K. ;
Piemonti, Lorenzo ;
Rodríguez-Gallego, Carlos ;
Notarangelo, Luigi ;
Su, Helen C. ;
Kisand, Kai ;
Okada, Satoshi ;
Puel, Anne ;
Jouanguy, Emmanuelle ;
Rice, Charles M. ;
Tiberghien, Pierre ;
Zhang, Qian ;
Casanova, Jean-Laurent ;
Abel, Laurent ;
Cobat, Aurélie ;
Universitat Autònoma de Barcelona
There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. [...]
2022 - 10.1073/pnas.2200413119
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 (may 2022)
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4.
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10 p, 1.1 MB |
COVID-19 and stem cell transplantation; results from an EBMT and GETH multicenter prospective survey
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Ljungman, Per (Karolinska Institutet (Estocolm, Suècia)) ;
de la Camara, Rafael (Hospital Universitario de la Princesa (Madrid)) ;
Mikulska, Malgorzata (Division of Infectious Diseases. University of Genoa and Ospedale Policlinico San Martino) ;
Tridello, G. (Pediatric Hematology Oncology) ;
Aguado, Beatriz (Instituto de Investigación Hospital Universitario de la Princesa) ;
Zahrani, M.A. (King Abdul - Aziz Medical City) ;
Apperley, Jane (Centre for Haematology. Imperial College) ;
Berceanu, A. (Hopital Jean Minjoz) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Calbacho, Maria (Hospital Universitario 12 de Octubre (Madrid)) ;
Ciceri, Fabio (Ospedale San Raffaele s.r.l.) ;
Lopez-Corral, L. (Hematology Department. Complejo Asistencial Universitario de Salamanca-IBSAL; Centro de Investigación del Cáncer-IBMCC) ;
Crippa, C. (Spedali Civili) ;
Fox, M.L. (Vall d'Hebron Institut d'Oncologia) ;
Grassi, A. (ASST Papa Giovanni XXIII) ;
Jimenez, M.J. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Demir, S.K. (HSCT unit. Demiroglu Bilim University) ;
Kwon, Mi (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Llamas, C.V. (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Lorenzo, J.L.L. (Hospital Universitario Fundación Jiménez Díaz) ;
Mielke, S. (Karolinska Institutet (Estocolm, Suècia). Department of Laboratory Medicine) ;
Orchard, K. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Porras, R.P. (Hospital Duran i Reynals (Hospitalet del Llobregat)) ;
Vallisa, D. (Hospital Guglielmo da Saliceto) ;
Xhaard, A. (Hôpital St. Louis) ;
Knelange, N.S. (EBMT Data Office. Department of Medical Statistics & Bioinformatics) ;
Cedillo, Angel (GETH Spanish Registry) ;
Kroeger, Nicolaus (Department of Stem cell Transplantation. University Hospital Eppendorf) ;
Piñana, José Luis (Hospital Clínic Universitari (València)) ;
Styczynski, Jan (Pediatric Hematology and Oncology. University Hospital. Collegium Medicum. Nicolaus Copernicus University Torun)
This study reports on 382 COVID-19 patients having undergone allogeneic (n = 236) or autologous (n = 146) hematopoietic cell transplantation (HCT) reported to the European Society for Blood and Marrow Transplantation (EBMT) or to the Spanish Group of Hematopoietic Stem Cell Transplantation (GETH). [...]
2021 - 10.1038/s41375-021-01302-5
Leukemia, Vol. 35 Núm. 10 (october 2021) , p. 2885-2894
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5.
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15 p, 1.8 MB |
COVID-19 infection in adult patients with hematological malignancies : a European Hematology Association Survey (EPICOVIDEHA)
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Pagano, Livio (Università Cattolica del Sacro Cuore) ;
Salmanton-García, Jon (University of Cologne) ;
Marchesi, Francesco (IRCCS Regina Elena National Cancer Institute) ;
Busca, Alessandro (AOU Citta' Della Salute E Della Scienza) ;
Corradini, Paolo (University of Milan) ;
Hoenigl, Martin (Medical University of Graz) ;
Klimko, Nikolai (North-Western State Medical University Named After Iliá Ilich Méchnikov (Sant Petersburg, Rússia)) ;
Koehler, Philipp (University of Cologne. Faculty of Medicine) ;
Pagliuca, Antonio (King's College Hospital NHS Foundation Trust) ;
Passamonti, Francesco (University of Insubria) ;
Verga, Luisa (Università Milano-Bicocca) ;
Víšek, Benjamin (University Hospital Hradec Kralove (República Txeca)) ;
Ilhan, Osman (Ankara University) ;
Nadali, Gianpaolo (Policlinico Borgo Roma Verona (Verona, Itàlia)) ;
Weinbergerová, Barbora (University Hospital Brno (República Txeca)) ;
Cordoba, Raul (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Marchetti, Monia (Azienda Ospedaliera Nazionale SS. Antonio E Biagio E Cesare Arrigo) ;
Collins, Graham (NIHR Oxford Biomedical Research Centre) ;
Farina, Francesca (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Cattaneo, Chiara (ASST-Spedali Civili) ;
Cabirta, Alba (Hospital Universitari Vall d'Hebron) ;
Gomes da Silva, Maria (Portuguese Institute of Oncology) ;
Itri, Federico (San Luigi Gonzaga Hospital - Orbassano) ;
van Doesum, Jaap A (University Medical Center Groningen) ;
Ledoux, Marie-Pierre (ICANS) ;
Čerňan, Martin (University Hospital Olomouc (Olomouc, República Txeca)) ;
Jakšić, Ozren (University Hospital Dubrava) ;
Duarte, Rafael (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Magliano, Gabriele (ASST Grande Ospedale Metropolitano Niguarda (Milà, Itàlia)) ;
Omrani, Ali S. (Communicable Disease Center, Hamad Medical Corporation) ;
Fracchiolla, Nicola (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Kulasekararaj, Austin (King's College London) ;
Valković, Toni (University of Rijeka. Faculty of Medicine) ;
Poulsen, Christian Bjørn (Zealand University Hospital) ;
Machado, Marina (Hospital General Universitario Gregorio Marañón) ;
Glenthøj, Andreas (University of Copenhagen) ;
Stoma, Igor (Gomel State Medical University) ;
Ráčil, Zdeněk (Institute of Hematology and Blood Transfusion) ;
Piukovics, Klára (University of Szeged. Department of Internal Medicine) ;
Navrátil, Milan (University Hospital Ostrava) ;
Emarah, Ziad (Mansoura University. Oncology Center) ;
Sili, Uluhan (Marmara University) ;
Maertens, Johan (KU Leuven) ;
Blennow, Ola (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Bergantim, Rui (University of Porto) ;
Garcia-Vidal, Carolina (Hospital Clínic i Provincial de Barcelona) ;
Prezioso, Lucia (U.O. Ematologia E Centro Trapianti Midollo Osseo, Ospedale Maggiore) ;
Guidetti, Anna (Fondazione IRCCS Istituto Nazionale Dei Tumori) ;
del Principe, Maria Ilaria (University of Rome Tor Vergata. Department of Biomedicine and Prevention) ;
Popova, Marina (Pavlov University) ;
De Jonge, Nick (Amsterdam UMC, Location VUmc) ;
Ormazabal-Vélez, Irati (Complejo Hospitalario de Navarra) ;
Fernández, Noemí (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Falces-Romero, Iker (Hospital Universitario La Paz (Madrid)) ;
Cuccaro, Annarosa (Azienda USL Toscana NordOvest (Livorno, Itàlia)) ;
Meers, Stef (AZ Klina) ;
Buquicchio, Caterina (Ematologia Con Trapianto, Ospedale Dimiccoli Barletta, Barletta, Italy) ;
Antić, Darko (University of Belgrade. Faculty of Medicine) ;
Al-Khabori, Murtadha (Sultan Qaboos University Hospital) ;
García-Sanz, Ramón (IBSAL, Centro de Investigación del Cáncer-IBMCC) ;
Biernat, Monika M. (Wroclaw Medical University) ;
Tisi, Maria Chiara (San Bortolo Hospital. Cell Therapy and Hematology) ;
Sal, Ertan (University of Cologne, Faculty of Medicine and University Hospital Cologne. Cologne Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases) ;
Rahimli, Laman (University of Cologne. Faculty of Medicine) ;
Čolović, Natasa (University of Belgrade. Faculty of Medicine) ;
Schönlein, Martin (University Medical Center Hamburg-Eppendorf. Department of Oncology, Hematology and Bone Marrow Transplantation With Section of Pneumology) ;
Calbacho, Maria (Hospital Universitario 12 de Octubre (Madrid)) ;
Tascini, Carlo (Azienda Sanitaria Universitaria del Friuli Centrale (Udine, Itàlia)) ;
Miranda-Castillo, Carolina (Hospital Universitario Rey Juan Carlos (Madrid)) ;
Khanna, Nina (University Hospital Basel (Basilea, Suïssa)) ;
Méndez, Gustavo-Adolfo (Hospital Escuela de Agudos Dr. Ramón Madariaga, Posadas, Argentina) ;
Petzer, Verena (Medical University of Innsbruck. Department of Hematology and Oncology) ;
Novák, Jan (University Hospital of Královské Vinohrady) ;
Besson, Caroline (Centre Hospitalier de Versailles) ;
Duléry, Rémy (Sorbonne Université) ;
Lamure, Sylvain (Universite de Montpellier. Departement d'Hematologie Clinique) ;
Nucci, Marcio (Federal University of Rio de Janeiro) ;
Zambrotta, Giovanni (Università Milano-Bicocca) ;
Žák, Pavel (University Hospital Hradec Kralove (República Txeca)) ;
Seval, Guldane Cengiz (Ankara University) ;
Bonuomo, Valentina (Policlinico Borgo Roma Verona, Verona, Italy) ;
Mayer, Jiří (University Hospital Brno (República Txeca)) ;
López-García, Alberto (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Sacchi, Maria Vittoria (Azienda Ospedaliera Nazionale SS. Antonio E Biagio E Cesare Arrigo. Hematology and BMT Unit) ;
Booth, Stephen (NIHR Oxford Biomedical Research Centre, Churchill Hospital) ;
Ciceri, Fabio (IRCCS San Raffaele Scientific Institute. Hematology and Bone Marrow Transplantation) ;
Oberti, Margherita (ASST-Spedali Civili) ;
Salvini, Marco (University of Insubria) ;
Izuzquiza, Macarena (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Nunes-Rodrigues, Raquel (Portuguese Institute of Oncology) ;
Ammatuna, Emanuele (University Medical Center Groningen) ;
Obr, Aleš (Palacky University. University Hospital Olomouc) ;
Herbrecht, Raoul (ICANS) ;
Núñez-Martín-Buitrago, Lucía (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Mancini, Valentina (ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy) ;
Shwaylia, Hawraa (National Center for Cancer Care and Research, Hamad Medical Corporation) ;
Sciumè, Mariarita (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Essame, Jenna (King's College Hospital NHS Foundation Trust) ;
Nygaard, Marietta (Zealand University Hospital) ;
Batinić, Josip (University of Zagreb. Faculty of Medicine) ;
Gonzaga, Yung (Instituto Nacional Do Cancer. Hematology Service) ;
Regalado-Artamendi, Isabel (Hospital General Universitario Gregorio Marañón) ;
Karlsson, Linda Katharina (University of Copenhagen) ;
Shapetska, Maryia (Scientific and Practical Center for Surgery, Transplantology and Hematology (Mins, Bielorússia)) ;
Hanakova, Michaela (Institute of Hematology and Blood Transfusion) ;
El-Ashwah, Shaimaa (Mansoura University. Oncology Center) ;
Borbényi, Zita (University of Szeged. Department of Internal Medicine) ;
Çolak, Gökçe Melis (Marmara University) ;
Nordlander, Anna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Dragonetti, Giulia (Università Cattolica del Sacro Cuore) ;
Maraglino, Alessio Maria Edoardo (Università Cattolica del Sacro Cuore) ;
Rinaldi, Amelia (U.O. Ematologia E Centro Trapianti Midollo Osseo, Ospedale Maggiore) ;
De Ramón-Sánchez, Cristina (Instituto de Investigación Biomédica de Salamanca) ;
Cornely, Oliver A. (German Centre for Infection Research (DZIF))
Patients with hematological malignancies (HM) are at high risk of mortality from SARS-CoV-2 disease 2019 (COVID-19). A better understanding of risk factors for adverse outcomes may improve clinical management in these patients. [...]
2021 - 10.1186/s13045-021-01177-0
Journal of hematology & oncology, Vol. 14 (october 2021)
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6.
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17 p, 2.5 MB |
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
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Bastard, Paul (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Rosen, Lindsey B. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Zhang, Qian (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Michailidis, Eleftherios (The Rockefeller University. Laboratory of Virology and Infectious Disease) ;
Hoffmann, Hans-Heinrich (The Rockefeller University. Laboratory of Virology and Infectious Disease) ;
Zhang, Yu (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Dorgham, Karim (Sorbonne Université. Centre d'Immunologie et des Maladies Infectieuses) ;
Philippot, Quentin (University of Paris. Imagine Institute) ;
Rosain, Jérémie (University of Paris. Imagine Institute) ;
Béziat, Vivien (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Manry, Jeremy (University of Paris. Imagine Institute) ;
Shaw, Elana (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Haljasmägi, Liis (University of Tartu. Institute of Biomedicine and Translational Medicine) ;
Peterson, Pärt (University of Tartu. Institute of Biomedicine and Translational Medicine) ;
Lorenzo, Lazaro (University of Paris. Imagine Institute) ;
Bizien, Lucy (University of Paris. Imagine Institute) ;
Trouillet-Assant, Sophie (Lyon University. International Center of Research in Infectiology) ;
Dobbs, Kerry (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Almeida de Jesus, Adriana (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Belot, Alexandre (Lyon Immunopathology Federation. Hospices Civils de Lyon) ;
Kallaste, Anne (Internal Medicine Clinic. Tartu University Hospital) ;
Catherinot, Emilie (Hôpital Foch) ;
Tandjaoui-Lambiotte, Yacine (Avicenne Hospital. Assistance Publique Hôpitaux de Paris) ;
Le Pen, Jérémie (The Rockefeller University. Laboratory of Virology and Infectious Disease) ;
Kerner, Gaspard (University of Paris. Imagine Institute) ;
Bigio, Benedetta (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Seeleuthner, Yoann (University of Paris. Imagine Institute) ;
Yang, Rui (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Bolze, Alexandre (Helix) ;
Spaan, András N. (University Medical Center Utrecht) ;
Delmonte, Ottavia M. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Abers, Michael S. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Aiuti, Alessandro (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Casari, Giorgio (Medical Genetics. IRCCS Ospedale San Raffaele) ;
Lampasona, Vito (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Piemonti, Lorenzo (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Ciceri, Fabio (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Bilguvar, Kaya (Yale University School of Medicine. Department of Genetics) ;
Lifton, Richard P. (Rockefeller University. Laboratory of Human Genetics and Genomics) ;
Vasse, Marc (Consorcio Hospital. General Universitario) ;
Smadja, David M. (Paris University. European Georges Pompidou Hospital) ;
Migaud, Mélanie (University of Paris. Imagine Institute) ;
Hadjadj, Jérome (Hôpital Cochin. Department of Internal Medicine) ;
Terrier, Benjamin (Université de Paris. Department of Internal Medicine) ;
Duffy, Darragh (Pasteur Institute) ;
Quintana-Murci, Lluis (Institut Pasteur. Collège de France) ;
van de Beek, Diederik (Amsterdam UMC. University Medical Center) ;
Roussel, Lucie (McGill University Health Centre) ;
Vinh, Donald C. (McGill University Health Centre) ;
Tangye, Stuart (Garvan Institute of Medical Research (Darlinghurst, Austràlia)) ;
Haerynck, Filomeen (Ghent University Hospital. (Bèlgica)) ;
Dalmau, David (Fundació Docència i Recerca Mútua Terrassa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brodin, Petter (Karolinska Institutet (Estocolm, Suècia)) ;
Nussenzweig, Michel (Howard Hughes Medical Institute) ;
Boisson-Dupuis, Stephanie (The Rockefeller University. St. Giles Laboratory of Human Genetics of Infectious Diseases) ;
Rodríguez-Gallego, Carlos (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Vogt, Guillaume (University of Paris. Neglected Human Genetics Laboratory) ;
Mogensen, Trine Hyrup (Aarhus University) ;
Oler, Andrew J. (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ;
Gu, Jingwen (Bioinformatics and Computational Biosciences Branch. Office of Cyber Infrastructure and Computational Biology. NIAID. NIH) ;
Burbelo, Peter D. (Division of Intramural Research. National Institute of Dental Craniofacial Research (NIDCR). NIH) ;
Cohen, Jeffrey I. (Laboratory of Infectious Diseases. Division of Intramural Research. NIAID. NIH) ;
Biondi, Andrea (Pediatric Department. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBMOspedale) ;
Bettini, Laura Rachele (Pediatric Department. Centro Tettamanti-European Reference Network PaedCan. EuroBloodNet. MetabERN-University of Milano-Bicocca-Fondazione MBBMOspedale) ;
D'Angio, Mariella (University of Milano-Bicocca. Pediatric Department) ;
Bonfanti, Paolo (University of Milano-Bicocca. Department of Infectious Diseases) ;
Rossignol, Patrick (University of Lorraine. Plurithematic Clinical Investigation Centre) ;
Mayaux, Julien (APHP Pitié-Salpêtrière Hospital) ;
Rieux-Laucat, Frédéric (Laboratory of Immunogenetics of Pediatric Autoimmune Diseases. INSERM. UMR 1163. University of Paris. Imagine Institute) ;
Husebye, Eystein (Karolinska Institutet (Estocolm, Suècia). Department of Medicine) ;
Fusco, Francesca (Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'. IGB-CNR) ;
Ursini, Matilde Valeria (Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso'. IGB-CNR) ;
Imberti, Luisa (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ;
Sottini, Alessandra (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ;
Paghera, Simone (Centro di Ricerca Emato-oncologica AIL (CREA) Laboratory. Diagnostic Department. ASST Spedali Civili di Brescia) ;
Quiros-Roldan, Eugenia (Department of Infectious and Tropical Diseases. University of Brescia. ASST Spedali di Brescia) ;
Rossi, Camillo (Direzione Sanitaria. ASST Spedali Civili di Brescia) ;
Castagnoli, Riccardo (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ;
Montagna, Daniela (Department of Clinical. Surgical. Diagnostic and Pediatric Sciences. University of Pavia) ;
Licari, Amelia (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ;
Marseglia, Gian Luigi (Department of Pediatrics. Fondazione IRCCS Policlinico San Matteo. University of Pavia) ;
Duval, Xavier (Centre d'Investigation Clinique. Inserm CIC 1425. Hôpital Bichat Claude Bernard. APHP) ;
Ghosn, Jade (Hôpital Bichat) ;
Tsang, John S. (Multiscale Systems Biology Section. Laboratory of Immune System Biology. NIAID. NIH) ;
Goldbach-Mansky, Raphaela (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Kisand, Kai (Institute of Biomedicine and Translational Medicine. University of Tartu) ;
Lionakis, Michail S. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Puel, Anne (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Zhang, Shein-Ying (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Holland, Steven M. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Gorochov, Guy (Département d'Immunologie. AP-HP. Hôpital Pitié-Salpétrière) ;
Jouanguy, Emmanuelle (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Rice, Charles M. (Laboratory of Virology and Infectious Disease. The Rockefeller University) ;
Cobat, Aurélie (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Notarangelo, Luigi (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Abel, Laurent (St. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. The Rockefeller University) ;
Su, Helen C. (National Institute of Allergy and Infectious Diseases (Maryland, Estats Units d'Amèrica)) ;
Casanova, Jean-Laurent (Pediatric Hematology and Immunology Unit. Necker Hospital for Sick Children. AP-HP) ;
The University of Hong Kong
HGID Lab ;
The University of Hong Kong
NIAID-USUHS Immune Response to COVID Group ;
COVID Clinicians ;
COVID-STORM Clinicians ;
Imagine COVID Group ;
French COVID Cohort Study Group ;
The Milieu Intérieur Consortium ;
CoV-Contact Cohort ;
Amsterdam UMC Covid-19 Biobank ;
COVID Human Genetic Effort ;
Universitat Autònoma de Barcelona
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-w (IFN-w) (13 patients), against the 13 types of IFN-a (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. [...]
2020 - 10.1126/science.abd4585
Science, Vol. 370 Núm. 6515 (september 2020) , p. eabd4585
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13 p, 1.0 MB |
Post-transplant cyclophosphamide after matched sibling, unrelated and haploidentical donor transplants in patients with acute myeloid leukemia : A comparative study of the ALWP EBMT
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Sanz, Jaime (Centro de Investigación Biomédica en Red de Cáncer) ;
Galimard, J. E. (EBMT Paris Office. Hospital Saint Antoine) ;
Labopin, Myriam (Department of Hematology. Hopital Saint Antoine. Sorbonne University) ;
Afanasyev, B. (First State Pavlov Medical University of St. Petersburg. Raisa Gorbacheva Mem. Research Institute for Paediatric Oncology. Hematology. and Transplantation) ;
Angelucci, Emanuele (Department of Haematology. IRCCS Ospedale Policlinico San Martino) ;
Ciceri, Fabio (Haematology and BMT) ;
Blaise, Didier (Programme de Transplantation and Therapie Cellulaire. Centre de Recherche en Cancérologie de Marseille. Institut Paoli Calmettes) ;
Cornelissen, J. J. (Department of Hematology. Erasmus MC Cancer Institute. University Medical Center Rotterdam) ;
Meijer, E. (Department of Hematology (Br 250). VU University Medical Center) ;
Diez-Martin, J. L. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Koc, Y. (Stem Cell Transplant Unit. Medical Park Hospitals) ;
Rovira Tarrats, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Castagna, L. (Transplantation Unit. Department of Oncology and Haematology. Istituto Clinico Humanitas) ;
Savani, B. N. (Vanderbilt University Medical Center) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (ALWP of the EBMT Office. Saint Antoine Hospital) ;
Mohty, Mohamad (Department of Hematology. Hopital Saint Antoine. Sorbonne University) ;
Universitat Autònoma de Barcelona
Background: The use of post-transplant cyclophosphamide (PTCy) is highly effective in preventing graft-versus-host disease (GVHD) in the haploidentical (Haplo) transplant setting and is being increasingly used in matched sibling (MSD) and matched unrelated (MUD) transplants. [...]
2020 - 10.1186/s13045-020-00882-6
Journal of hematology & oncology, Vol. 13 Núm. 1 (june 2020) , p. 46
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11 p, 572.5 KB |
Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients : a position statement from an international expert group
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Mohty, Mohamad (Hematology Department. AP-HP. Hôpital Saint-Antoine. Sorbonne Université) ;
Malard, F. (Hematology Department. AP-HP. Hôpital Saint-Antoine. Sorbonne Université) ;
Abecasis, Manuel (Instituto Portugues de Oncologia) ;
Aerts, E. (University Hospital Zurich (Suïssa)) ;
Alaskar, A. S. (Department of Oncology. King Abdulaziz Medical City. King Abdullah International Medical Research Center. King Saud Bin Abdulaziz University for Health Sciences. Ministry of National Guard Health Affairs) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre) ;
Arat, Mutlu (HSCT Unit. Sisli Florence Nightingale Hospital) ;
Bader, Peter (Division for Stem Cell Transplantation and Immunology. Department for Children and Adolescents. University Hospital. Goethe University) ;
Baron, Frederic (CHU and University of Liege) ;
Basak, G. (Medical University of Warsaw) ;
Bazarbachi, A. (American University of Beirut. Department of Internal Medicine) ;
Blaise, Didier (Transplant and Cellular Immunotherapy Program. Department of Hematology. Aix-Marseille Univ. Inserm. CNRS. Institut Paoli-Calmettes. CRCM) ;
Ciceri, Fabio (Hematology and Bone Marrow Transplantation Unit. IRCCS Ospedale San Raffaele. University Vita-Salute) ;
Corbacioglu, Selim (Department of Pediatric Hematology. Oncology and Stem Cell Transplantation. University of Regensburg) ;
Dalle, J. H. (Department of Hematology and Immunology. Hospital Robert Debre. Paris 7-Paris Diderot University) ;
Dignan, F. (Department of Clinical Haematology. Central Manchester Foundation Trust) ;
Fukuda, T. (HSCT Division. National Cancer Center Hospital) ;
Huynh, A. (Institut Universitaire du Cancer Toulouse-Oncopole) ;
Kuball, J. (Department of Haematology. University Medical Centre) ;
Lachance, S. (Department of Hematology and Stem Cell Transplant Program. Hôpital Maisonneuve-Rosemont. University of Montreal) ;
Lazarus, H. (Case Western Reserve University) ;
Masszi, T. (St László Hospital (Hongria)) ;
Michallet, M. (Hematology Department. Groupement Hospitalier Sud. Hospices Civils de Lyon. Université Claude Bernard Lyon EST) ;
Nagler, Arnon (Hematology and Bone Marrow Transplantation. Chaim Sheba Medical Center) ;
NiChonghaile, M. (Trinity College Dublin) ;
Okamoto, S. (Division of Hematology. Department of Medicine. Keio University School of Medicine) ;
Pagliuca, A. (King's College Hospital NHS Foundation Trust) ;
Peters, C. (Department of Pediatrics. St. Anna Kinderspital) ;
Petersen, F. B. (LDS Hospital) ;
Richardson, Paul G.. (Division of Hematology. Mayo Clinic) ;
Ruutu, T. (Helsinki University Hospital (Finlàndia)) ;
Saber, Wael (Center for International Blood and Marrow Transplant Research. Medical College of Wisconsin) ;
Savani, B. N. (Hematology and Stem Cell Transplantation Section. Division of Hematology/Oncology. Department of Medicine. Vanderbilt University Medical Center and Veterans Affairs Medical Center) ;
Soiffer, R. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Division of Hematologic Malignancies) ;
Styczynski, Jan (Pediatric Hematology and Oncology. University Hospital. Collegium Medicum UMK) ;
Wallhult, E. (Sahlgrenska University Hospital (Suècia)) ;
Yakoub-Agha, Ibrahim (CHU de Lille. LIRIC INSERM U995. Université de Lille2) ;
Duarte, Rafael (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Carreras, Enric (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Universitat Autònoma de Barcelona
2020 - 10.1038/s41409-019-0705-z
Bone marrow transplantation, Vol. 55 Núm. 3 (january 2020) , p. 485-495
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