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13 p, 7.8 MB |
Role of PATJ in stroke prognosis by modulating endothelial to mesenchymal transition through the Hippo/Notch/PI3K axis
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Medina-Dols, Aina (Hospital Universitari Son Espases) ;
Cañellas, Guillem (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Capó, Toni (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Solé Piñol, Montserrat (Hospital Universitari Vall d'Hebron) ;
Mola-Caminal, Marina (Uppsala University) ;
Cullell, Natalia (Institut de Recerca Sant Pau) ;
Jaume, Marina (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Nadal-Salas, Laura (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Llinàs, Jaume (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Gómez, Lluis (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Tur, Silvia (Hospital Universitari Son Espases (HUSE)) ;
Jiménez, Carmen (Hospital Universitari Son Espases (HUSE)) ;
Díaz, Rosa M. (Hospital Universitari Son Espases (HUSE)) ;
Carrera, Caty (Institut de Recerca Sant Pau) ;
Muiño, Elena (Institut de Recerca Sant Pau) ;
Gallego-Fabrega, Cristina (Institut de Recerca Sant Pau) ;
Soriano Tárraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ruiz-Guerra, Laura (Hospital Universitari Son Espases) ;
Pol-Fuster, Josep (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Asensio, Víctor (Hospital Universitari Son Espases (HUSE)) ;
Muncunill Farreny, Josep (Fundación Instituto de Investigación Sanitaria Islas Baleares (IdISBa)) ;
Fleischer, Aarne (Fundación Instituto de Investigación Sanitaria Islas Baleares (IdISBa)) ;
Iglesias, Amanda (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lazcano, Uxue (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Fernández-Pérez, Isabel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Jiménez-Balado, Joan (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gabriel Salazar, Marina (Hospital Universitari Vall d'Hebron) ;
García-Gabilondo, Miguel (Hospital Universitari Vall d'Hebron) ;
Lei, Ting (Hospital Universitari Vall d'Hebron) ;
Torres-Aguila, Nuria P. (Institut de Recerca Sant Pau) ;
Cárcel-Márquez, Jara (Institut de Recerca Sant Pau) ;
Lladó, Jerònia (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Olmos, Gabriel (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Rosell Novel, Anna (Hospital Universitari Vall d'Hebron) ;
Montaner, Joan (Hospital Universitario Virgen del Rocío) ;
Planas, Anna Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ;
Rabionet, Raquel (Instituto de Salud Carlos III) ;
Hernandez Guillamon, Maria Mar (Hospital Universitari Vall d'Hebron) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Fernandez-Cadenas, Israel (Institut de Recerca Sant Pau) ;
Vives-Bauzá, Cristòfol (Institut Universitari d'Investigacions en Ciències de la Salut (IUNICS)) ;
Universitat Autònoma de Barcelona
Through GWAS studies we identified PATJ associated with functional outcome after ischemic stroke (IS). The aim of this study was to determine PATJ role in brain endothelial cells (ECs) in the context of stroke outcome. [...]
2024 -  10.1038/s41420-024-01857-z
Cell Death Discovery, Vol. 10 (february 2024)
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19 p, 2.4 MB |
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
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Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sitlani, Collen M. (University of Washington) ;
Bone, William P. (University of Pennsylvania) ;
Martín Bórnez, Miguel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Voight, Benjamin F. (University of Pennsylvania Perelman School of Medicine) ;
Morrison, Alanna C. ;
Damrauer, Scott M. ;
de Vries, Paul S. ;
Smith, Nicholas L. ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Dehghan, Abbas ;
Heath, Adam S. ;
Reiner, Alex P. ;
Johnson, Andrew ;
Richmond, Anne ;
Peters, Annette ;
van Hylckama Vlieg, Astrid ;
McKnight, Barbara ;
Psaty, Bruce M. ;
Hayward, Caroline ;
Ward-Caviness, Cavin ;
O'Donnell, Cristopher ;
Chasman, Daniel ;
Strachan, David P. ;
Tregouet, David A. ;
Mook-Kanamori, Dennis ;
Gill, Dipender ;
Thibord, Florian ;
Asselbergs, Folkert W. ;
Leebeek, Frank W. G. ;
Rosendaal, Frits R. ;
Davies, Gail ;
Homuth, Georg ;
Temprano, Gerard ;
Campbell, Harry ;
Taylor, Herman A. ;
Bressler, Jan ;
Huffman, Jennifer E. ;
Rotter, Jerome I. ;
Yao, Jie ;
Wilson, James F. ;
Bis, Joshua C. ;
Hahn, Julie M. ;
Desch, Karl C. ;
Wiggins, Kerri L. ;
Raffield, Laura M. ;
Bielak, Lawrence F. ;
Yanek, Lisa R. ;
Kleber, Marcus E. ;
Mueller, Martina ;
Kavousi, Maryam ;
Mangino, Massimo ;
Liu, Melissa ;
Brown, Michael R. ;
Conomos, Matthew P. ;
Jhun, Min-A. ;
Chen, Ming-Huei ;
de Maat, Moniek P. M. ;
Pankratz, Nathan ;
Smith, Nicholas L. ;
Peyser, Patricia A. ;
Elliot, Paul ;
Wei, Peng ;
Wild, Philipp S. ;
Morange, Pierre E. ;
van der Harst, Pim ;
Yang, Qiong ;
Le, Ngoc-Quynh ;
Marioni, Riccardo ;
Li, Ruifang ;
Damrauer, Scott M. ;
Cox, Simon R. ;
Trompet, Stella ;
Felix, Stephan B. ;
Völker, Uwe ;
Tang, Weihong ;
Koenig, Wolfgang ;
Jukema, J. Wouter ;
Guo, Xiuqing ;
Lindstrom, Sara ;
Wang, Lu ;
Smith, Erin N. ;
Gordon, William ;
van Hylckama Vlieg, Astrid ;
de Andrade, Mariza ;
Brody, Jennifer A. ;
Pattee, Jack W. ;
Haessler, Jeffrey ;
Brumpton, Ben M. ;
Suchon, Pierre ;
Chen, Ming-Huei ;
Turman, Constance ;
Germain, Marine ;
Wiggins, Kerri L. ;
MacDonald, James ;
Braekkan, Sigrid K. ;
Armasu, Sebastian M. ;
Pankratz, Nathan ;
Jackson, Rabecca D. ;
Nielsen, Jonas B. ;
Giulianini, Franco ;
Puurunen, Marja K. ;
Ibrahim, Manal ;
Heckbert, Susan R. ;
Bammler, Theo K. ;
Frazer, Kelly A. ;
McCauley, Bryan M. ;
Taylor, Kent ;
Pankow, James S. ;
Reiner, Alexander P. ;
Gabrielsen, Maiken E. ;
Deleuze, Jean-François ;
O'Donnell, Chris J. ;
Kim, Jihye ;
McKnight, Barbara ;
Kraft, Peter ;
Hansen, John-Bjarne ;
Rosendaal, Frits R. ;
Heit, John A. ;
Psaty, Bruce M. ;
Tang, Weihong ;
Kooperberg, Charles ;
Hveem, Kristian ;
Ridker, Paul M. ;
Morange, Pierre-Emmanuel ;
Johnson, Andrew D. ;
Kabrhel, Christopher ;
Trégouët, David-Alexandre ;
Smith, Nicholas L. ;
Malik, Rainer ;
Chauhan, Ganesh ;
Traylor, Matthew ;
Sargurupremraj, Muralidharan ;
Okada, Yukinori ;
Mishra, Aniket ;
Rutten-Jacobs, Loes ;
Giese, Anne-Katrin ;
van der Laan, Sander W. ;
Gretarsdottir, Solveig ;
Anderson, Christopher D. ;
Chong, Michael ;
Adams, Hieab HH. ;
Ago, Tetsuro ;
Almgren, Peter ;
Amouyel, Philippe (Institut Pasteur de Lille) ;
Ay, Hakan ;
Bartz, Traci M. ;
Benavente, Oscar R. ;
Bevan, Steve ;
Boncoraglio, Giorgio B. ;
Brown, Robert D. ;
Butterworth, Aadam S. ;
Carrera, Caty ;
Carty, Cara L. ;
Chen, Wei-Min ;
Cole, John W. ;
Correa, Adolfo ;
Cotlarciuc, Ioanna ;
Cruchaga, Carlos ;
Danesh, John ;
de Bakker, Paul I. W. ;
DeStefano, Anita L. ;
den Hoed, Marcel ;
Duan, Qing ;
Engelter, Stefan T. ;
Falcone, Guido J. ;
Gottesman, Rebecca F. ;
Grewal, Raji P. ;
Gudnason, Vilmundur ;
Gustafsson, Stefan ;
Haessler, Jeffrey ;
Harris, Tamara B. ;
Hassan, Ahamad ;
Havulinna, Aki S. ;
Heckbert, Susan R. ;
Holliday, Elizabeth G. ;
Howard, George ;
Hsu, Fang-Chi ;
Hyacinth, Hyacinth I. ;
Arfan Ikram, M. ;
Ingelsson, Erik ;
Irvin, Marguerite R. ;
Jian, Xueqiu ;
Jiménez-Conde, Jordi ;
Johnson, Julie A. ;
Jukema, J. Wouter ;
Kanai, Masahiro ;
Keene, Keith L. ;
Kissela, Brett M. ;
Kleindorfer, Dawn O. ;
Kooperberg, Charles ;
Kubo, Michiaki ;
Lange, Leslie A. ;
Langefeld, Carl D. ;
Langenberg, Claudia ;
Launer, Lenore J. ;
Lee, Jin-Moo ;
Lemmens, Robin ;
Leys, Didier ;
Lewis, Cathryn M. ;
Lin, Wei-Yu ;
Lindgren, Arne G. ;
Lorentzen, Erik ;
Magnusson, Patrik K. ;
Maguire, Jane ;
Manichaikul, Ani ;
McArdle, Patrick F. ;
Meschia, James F. ;
Mitchell, Braxton D. ;
Mosley, Thomas H. ;
Nalls, Michael A. ;
Ninomiya, Toshiharu ;
O'Donnell, Martin J. ;
Psaty, Bruce M. ;
Pulit, Sara L. ;
Rannikmäe, Kristiina ;
Reiner, Alexander P. ;
Rexrode, Kathryn M. ;
Rice, Kenneth ;
Rich, Stephen S. ;
Ridker, Paul M. ;
Rost, Natalia S. ;
Rothwell, Peter M. ;
Rotter, Jerome I. ;
Rundek, Tatjana ;
Sacco, Ralph L. ;
Sakaue, Saori ;
Sale, Michele M. ;
Salomaa, Veikko ;
Sapkota, Bishwa R. ;
Schmidt, Reinhold ;
Schmidt, Carsten O. ;
Schminke, Ulf ;
Sharma, Pankaj ;
Slowik, Agnieszka ;
Sudlow, Cathie L. M. ;
Tanislav, Christian ;
Tatlisumak, Turgut ;
Taylor, Kent D. ;
Thijs, Vincent N. S. ;
Thorleifsson, Gudmar ;
Thorsteinsdottir, Unnur ;
Tiedt, Steffen ;
Trompet, Stella ;
Tzourio, Christophe ;
van Duijn, Cornelia M. ;
Walters, Matthew ;
Wareham, Nicholas J. ;
Wassertheil-Smoller, Sylvia ;
Wilson, James G. ;
Wiggins, Kerri L. ;
Yang, Qiong ;
Yusuf, Salim ;
Amin, Najaf ;
Aparicio, Hugo S. ;
Arnett, Donna K. ;
Attia, John ;
Beiser, Alexa S. ;
Berr, Claudine ;
Buring, Julie E. ;
Bustamante, Mariana ;
Caso, Valeria ;
Cheng, Yu-Ching ;
Hoan Choi, Seung ;
Chowhan, Ayesha ;
Cullell, Natalia ;
Dartigues, Jean-François ;
Delavaran, Hossein ;
Delgado, Pilar ;
Dörr, Marcus ;
Engström, Gunnar ;
Ford, Ian ;
Gurpreet, Wander S. ;
Hamsten, Anders ;
Heitsch, Laura ;
Hozawa, Aatsushi ;
Ibanez, Laura ;
Ilinca, Andrea ;
Ingelsson, Martin ;
Iwasaki, Motoki ;
Jackson, Rebecca D. ;
Jood, Katarina ;
Jousilahti, Pekka ;
Kaffashian, Sara ;
Kalra, Lalit ;
Kamouchi, Masahiro ;
Kitazono, Takanari ;
Kjartansson, Olafur ;
Kloss, Manja ;
Koudstaal, Peter J. ;
Krupinski, Jerzy ;
Labovitz, Daniel L. ;
Laurie, Cathy C. ;
Levi, Christhoper R. ;
Li, Linxin ;
Lind, Lars ;
Lindgren, Cecilia M. ;
Lioutas, Vasileios ;
Mei Liu, Yong ;
Lopez, Oscar L. ;
Makoto, Hirata ;
Martinez-Majander, Nicolas ;
Matsuda, Koichi ;
Minegishi, Naoko ;
Montaner, Joan ;
Morris, Andrew P. ;
Muiño, Elena ;
Müller-Nurasyid, Martina ;
Norrving, Bo ;
Ogishima, Soichi ;
Parati, Eugenio A. ;
Reddy Peddareddygari, Leema ;
Pedersen, Nancy L. ;
Pera, Joanna ;
Perola, Markus ;
Pezzini, Alessandro ;
Pileggi, Silvana ;
Rabionet, Raquel ;
Riba-Llena, Iolanda ;
Ribasés, Marta ;
Romero, Jose R. ;
Roquer, Jaume ;
Rudd, Anthony G. ;
Sarin, Antti-Pekka ;
Sarju, Ralhan ;
Sarnowski, Chloe ;
Sasaki, Makoto ;
Satizabal, Claudia L. ;
Satoh, Mamoru ;
Sattar, Naveed ;
Sawada, Norie ;
Sibolt, Gerli ;
Sigurdsson, Ásgeir ;
Smith, Albert ;
Sobue, Kenji ;
Soriano-Tárraga, Carolina ;
Stanne, Tara ;
Colin Stine, O. ;
Stott, David J. ;
Strauch, Konstantin ;
Takai, Takako ;
Tanaka, Hideo ;
Tanno, Kozo ;
Teumer, Alexander ;
Tomppo, Liisa ;
Torres-Aguila, Nuria P. ;
Touze, Emmanuel ;
Tsugane, Shoichiro ;
Uitterlinden, Aandre G. ;
Valdimarsson, Einar M. ;
van der Lee, Sven J. ;
Völzke, Henry ;
Wakai, Kenji ;
Weir, David ;
Williams, Stephen R. ;
Wolfe, Charles D.A. ;
Wong, Quenna ;
Xu, Huichun ;
Yamaji, Taiki ;
Sanghera, Dharambir K. ;
Melander, Olle ;
Jern, Christina ;
Strbian, Daniel ;
Fernandez-Cadenas, Israel ;
Longstreth, W.T. ;
Rolfs, Arndt ;
Hata, Jun ;
Woo, Daniel ;
Rosand, Jonathan ;
Pare, Guillaume ;
Hopewell, Jemma C. ;
Saleheen, Danish ;
Stefansson, Kari ;
Worrall, BradfordB. ;
Kittner, Steven J. ;
Seshadri, Sudha ;
Fornage, Myriam ;
Markus, Hugh S. ;
Howson, Joana M. M. ;
Kamatani, Yoichiro ;
Debette, Stephanie ;
Dichgans, Martin ;
Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 - 10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349
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11 p, 897.2 KB |
MRI Radiomic Signature of White Matter Hyperintensities Is Associated With Clinical Phenotypes
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Bretzner, Martin (University of Lille) ;
Bonkhoff, Anna K. (Massachusetts General Hospital) ;
Schirmer, Markus D. (Massachusetts General Hospital) ;
Hong, Sungmin (Massachusetts General Hospital) ;
Dalca, Adrian V. (Massachusetts Institute of Technology) ;
Donahue, Kathleen L. (Massachusetts General Hospital) ;
Giese, Anne-Katrin (Massachusetts General Hospital) ;
Etherton, Mark R. (Massachusetts General Hospital) ;
Rist, Pamela M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Nardin, Marco (Massachusetts General Hospital) ;
Marinescu, Razvan (Massachusetts Institute of Technology) ;
Wang, Clinton (Massachusetts Institute of Technology) ;
Regenhardt, Robert W. (Massachusetts General Hospital) ;
Leclerc, Xavier (University of Lille) ;
Lopes, Renaud (Institut Pasteur de Lille) ;
Benavente, Oscar R. (Department of Medicine, University of British Columbia) ;
Cole, John W. (Department of Neurology, University of Maryland School of Medicine a) ;
Donatti, Amanda (School of Medical Sciences, University of Campinas (Brasil)) ;
Griessenauer, Christoph J. (Paracelsus Medical University) ;
Heitsch, Laura (Department of Neurology, Washington University School of Medicine) ;
Holmegaard, Lukas (Sahlgrenska Academy at University of Gothenburg) ;
Jood, Katarina (University of Gothenburg) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kittner, Steven J. (Department of Neurology, University of Maryland School of Medicine) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Levi, Christopher R. (Department of Neurology, John Hunter Hospital) ;
McArdle, Patrick F. (Department of Medicine, University of Maryland School of Medicine) ;
McDonough, Caitrin W. (Department of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, University of Florida) ;
Meschia, James F. (Mayo Clinic (Estats Units d'Amèrica)) ;
Phuah, Chia-Ling (Department of Neurology, Washington University School of Medicine) ;
Rolfs, Arndt (Centogene (Alemanya)) ;
Ropele, Stefan (Department of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz) ;
Rosand, Jonathan (Massachusetts General Hospital) ;
Roquer, Jaume (Department of Neurology, University of Miami) ;
Rundek, Tatjana (Department of Neurology, University of Miami) ;
Sacco, Ralph L. (Department of Neurology University of Miami) ;
Schmidt, Reinhold (Department of Neurology, Medical University of Graz) ;
Sharma, Pankaj (St. Peter's Hospitals (Regne Unit)) ;
Slowik, Agnieszka (Department of Neurology, Jagiellonian University Medical College) ;
Sousa, Alessandro (Department of Neurology, University of Maryland School of Medicine) ;
Stanne, Tara M. (University of Gothenburg) ;
Strbian, Daniel (Department of Neurology, Helsinki University Central Hospital) ;
Tatlisumak, Turgut (Department of Neurology, Sahlgrenska University Hospital) ;
Thijs, Vincent (Florey Institute of Neuroscience and Mental Health, Department of Neurology Austin Health) ;
Vagal, Achala (Department of Radiology, University of Cincinnati College of Medicine) ;
Wasselius, Johan (Skåne University Hospital (Suècia)) ;
Woo, Daniel (Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine) ;
Wu, Ona (Massachusetts General Hospital) ;
Zand, Ramin (Department of Neurology, Geisinger) ;
Worrall, Bradford B. (Department of Neurology and Public Health Sciences, University of Virginia) ;
Maguire, Jane M. (University of Technology Sydney) ;
Lindgren, Arne (Department of Clinical Sciences Lund, Lund University) ;
Jern, Christina (Sahlgrenska Academy at University of Gothenburg) ;
Golland, Polina (Massachusetts Institute of Technology) ;
Kuchcinski, Grégory (University of Lille) ;
Rost, Natalia S. (Massachusetts General Hospital) ;
Universitat Autònoma de Barcelona
Neuroimaging measurements of brain structural integrity are thought to be surrogates for brain health, but precise assessments require dedicated advanced image acquisitions. By means of quantitatively describing conventional images, radiomic analyses hold potential for evaluating brain health. [...]
2021 - 10.3389/fnins.2021.691244
Frontiers in Neuroscience, Vol. 15 (july 2021)
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10 p, 678.7 KB |
Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke
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Hong, Sungmin (Massachusetts General Hospital) ;
Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ;
Schirmer, Markus D. (University Hospital Bonn) ;
Bonkhoff, Anna K. (Massachusetts General Hospital) ;
Bretzner, Martin (Université du Lille) ;
Rist, Pamela (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Dalca, Adrian V. (Department of Radiology, Massachusetts General Hospital) ;
Regenhardt, Robert W. (Massachusetts General Hospital) ;
Etherton, Mark R. (Massachusetts General Hospital) ;
Donahue, Kathleen L. (Massachusetts General Hospital) ;
Nardin, Marco (Harvard Medical School) ;
Mocking, Steven J. T. (Massachusetts General Hospital) ;
McIntosh, Elissa C. (Massachusetts General Hospital) ;
Attia, John (University of Newcastle) ;
Benavente, Oscar R. (University of British Columbia) ;
Cole, John W. (University of Maryland. School of Medicine) ;
Donatti, Amanda (University of Campinas) ;
Griessenauer, Christoph J. (Research Institute of Neurointervention, Paracelsus Medical University) ;
Heitsch, Laura (Washington University School of Medicine) ;
Holmegaard, Lukas (University of Gothenburg) ;
Jood, Katarina (University of Gothenburg) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kittner, Steven J. (University of Maryland School of Medicine) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Levi, Christopher R. (John Hunter Hospital) ;
McDonough, Caitrin W. (University of Florida) ;
Meschia, James F. (Mayo Clinic (Estats Units d'Amèrica)) ;
Phuah, Chia-Ling (Department of Neurology, Washington University School of Medicine & Barnes-Jewish Hospital) ;
Rolfs, Arndt (Centogene AG (Alemanya)) ;
Ropele, Stefan (Department of Neurology, Medical University Graz) ;
Rosand, Jonathan (Massachusetts General Hospital) ;
Rundek, Tatjana (Department of Neurology, University of Miami) ;
Sacco, Ralph L. (Department of Neurology , University of Miami) ;
Schmidt, Reinhold (Department of Neurology, Medical University Graz) ;
Enzinger, Christian (Department of Neurology, Medical University Graz) ;
Sharma, Pankaj (St. Peter's and Ashford Hospitals) ;
Slowik, Agnieszka (Jagiellonian University Medical College) ;
Sousa, Alessandro (University of Campinas) ;
Stanne, Tara M. (University of Gothenburg) ;
Strbian, Daniel (University of Helsinki) ;
Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ;
Thijs, Vincent (Austin Health (Austràlia)) ;
Vagal, Achala (University of Cincinnati College of Medicine) ;
Wasselius, Johan (Skåne University Hospital (Suècia)) ;
Woo, Daniel (University of Cincinnati College of Medicine) ;
Zand, Ramin (Geisinger (Estats Units d'Amèrica)) ;
McArdle, Patrick F. (University of Maryland School of Medicine) ;
Worrall, Bradford B. (University of Virginia) ;
Wu, Ona (Massachusetts General Hospital) ;
Jern, Christina (Department of University of Gothenburg) ;
Lindgren, Arne G. (Lund University. Department of Clinical Sciences) ;
Maguire, Jane (University of Technology Sydney) ;
Tomppo, Liisa (University of Helsinki) ;
Golland, Polina (Massachusetts Institute of Technology) ;
Rost, Natalia S. (Massachusetts General Hospital) ;
Universitat Autònoma de Barcelona
Objective: To personalize the prognostication of post-stroke outcome using MRI-detected cerebrovascular pathology, we sought to investigate the association between the excessive white matter hyperintensity (WMH) burden unaccounted for by the traditional stroke risk profile of individual patients and their long-term functional outcomes after a stroke. [...]
2021 - 10.3389/fneur.2021.700616
Frontiers in neurology, Vol. 12 (september 2021)
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19 p, 7.4 MB |
Rp11-362k2.2:Rp11-767i20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma. a gwas meta-analysis
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Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ;
Carrera, C. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Llucià-Carol, Laia (Institut d'Investigació Biomèdica Sant Pau) ;
Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Cullell, Natalia (Fundació MútuaTerrassa per la Docència i la Recerca) ;
Lledós, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Castillo, J. (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Sobrino, T. (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Campos, Francisco (Instituto de Investigación Sanitaria de Santiago (IDIS)) ;
Rodríguez-Castro, E. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Millán, M. (Institut Germans Trias i Pujol) ;
Muñoz-Narbona, L. (Institut Germans Trias i Pujol) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol) ;
López-Cancio, E. (Hospital Universitario Central de Asturias) ;
Ribó, M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron) ;
Jiménez-Conde, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Roquer, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Soriano-Tárraga, C. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Vives-Bauza, C. (Instituto de Investigación Sanitaria de Palma) ;
Díaz Navarro, R. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Tur, S. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Obach, V. (Hospital Clínic i Provincial de Barcelona) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Segura, T. (Complejo Hospitalario Universitario de Albacete) ;
Serrano-Heras, G. (Complejo Hospitalario Universitario de Albacete) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Delgado Mederos, Raquel (Institut d'Investigació Biomèdica Sant Pau) ;
Camps-Renom, Pol (Institut d'Investigació Biomèdica Sant Pau) ;
Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Guisado-Alonso, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Guasch-Jiménez, Marina (Institut d'Investigació Biomèdica Sant Pau) ;
Marín, Rebeca (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez-Domeño, Alejandro (Institut d'Investigació Biomèdica Sant Pau) ;
Freijo-Guerrero, M.D.M. (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Moniche, F. (Instituto de Biomedicina de Sevilla) ;
Cabezas, Juan Antonio (Instituto de Biomedicina de Sevilla) ;
Castellanos, M. (Complejo Hospitalario Universitario de A Coruña) ;
Krupinsky, J. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Strbian, D. (Helsinki University Hospital (Finlàndia)) ;
Tatlisumak, T. (Sahlgrenska University Hospital (Suècia)) ;
Thijs, V. (Austin Health. Department of Neurology) ;
Lemmens, R. (University Hospitals Leuven (Bèlgica)) ;
Slowik, A. (Jagiellonian University Medical College) ;
Pera, J. (Jagiellonian University Medical College) ;
Heitsch, Laura (Washington University School of Medicine) ;
Ibañez, Laura (Washington University School of Medicine) ;
Cruchaga, Carlos (Washington University School of Medicine) ;
Dhar, R. (Washington University School of Medicine) ;
Lee, J.M. (Washington University School of Medicine) ;
Montaner, J. (Instituto de Biomedicina de Sevilla) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase their frequency of use by extending the time-window administration, which may lead to an increase in complications such as hemorrhagic transformation, with parenchymal hematoma (PH) being the more severe subtype, associated with higher mortality and disability rates. [...]
2021 - 10.3390/jcm10143137
Journal of clinical medicine, Vol. 10 Núm. 14 (february 2021) , p. 3137
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6.
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17 p, 693.0 KB |
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke
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Jaworek, Thomas ;
Xu, Huichun ;
Gaynor, Brady ;
Cole, John W. ;
Rannikmae, Kristiina ;
Stanne, Tara M. ;
Tomppo, Liisa ;
Abedi, Vida ;
Amouyel, Philippe ;
Armstrong, Nicole D. ;
Attia, John ;
Bell, Steven ;
Benavente, Oscar R. ;
Boncoraglio, Giorgio B. ;
Butterworth, Adam ;
Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ;
Chen, Zhengming ;
Chong, Michael ;
Cruchaga, Carlos ;
Cushman, Mary ;
Danesh, John ;
Debette, Stéphanie ;
Duggan, David J. ;
Durda, Jon Peter ;
Engstrom, Gunnar ;
Enzinger, Chris ;
Faul, Jessica D. ;
Fecteau, Natalie S. ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Gieger, Christian ;
Giese, Anne-Katrin ;
Grewal, Raji P. ;
Grittner, Ulrike ;
Havulinna, Aki S. ;
Heitsch, Laura ;
Hochberg, Marc C. ;
Holliday, Elizabeth ;
Hu, Jie ;
Ilinca, Andreea ;
Irvin, Marguerite R. ;
Jackson, Rebecca D. ;
Jacob, Mina A. ;
Rabionet, Raquel ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Johnson, Julie A. ;
Kamatani, Yoichiro ;
Kardia, Sharon L.R. ;
Koido, Masaru ;
Kubo, Michiaki ;
Lange, Leslie ;
Lee, Jin-Moo ;
Lemmens, Robin ;
Levi, Christopher R. ;
Li, Jiang ;
Li, Liming ;
Lin, Kuang ;
Lopez, Haley ;
Luke, Sothear ;
Maguire, Jane ;
McArdle, Patrick F. ;
McDonough, Caitrin W. ;
Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ;
Metso, Tiina ;
Müller-Nurasyid, Martina ;
Dichgans, Martin ;
O'Donnell, Martin ;
Peddareddygari, Leema R. ;
Pera, Joanna ;
Perry, James A. ;
Peters, Annette ;
Putaala, Jukka ;
Ray, Debashree ;
Rexrode, Kathryn ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosand, Jonathan ;
Rothwell, Peter M. ;
Rundek, Tatjana ;
Ryan, Kathleen A. ;
Sacco, Ralph L. ;
Salomaa, Veikko ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Schmidt, Reinhold ;
Sharma, Pankaj ;
Slowik, Agnieszka ;
Smith, Jennifer A. ;
Smith, Nicholas L. ;
Wassertheil-Smoller, Sylvia ;
Söderholm, Martin ;
Stine, O. Colin ;
Strbian, Daniel ;
Sudlow, Cathie L.M. ;
Tatlisumak, Turgut ;
Terao, Chikashi ;
Thijs, Vincent ;
Torres-Aguila, Nuria P.. ;
Trégouët, David-Alexandre ;
Tuladhar, Anil M. ;
Veldink, Jan ;
Walters, Robin G. ;
Weir, David R. ;
Woo, Daniel ;
Worrall, Bradford B. ;
Hong, Charles C. ;
Ross, Owen A. ;
Zand, Ramin ;
de Leeuw, Frank-Erik ;
Lindgren, Arne G. ;
Paré, Guillaume ;
Anderson, Christopher D. ;
Markus, Hugh S. ;
Jern, Christina ;
Malik, Rainer ;
Dichgans, Martin ;
Mitchell, Braxton D. ;
Kittner, Steven J. ;
Universitat Autònoma de Barcelona
Current genome-wide association studies of ischemic stroke have focused primarily on late-onset disease. As a complement to these studies, we sought to identify the contribution of common genetic variants to risk of early-onset ischemic stroke. [...]
2022 - 10.1212/WNL.0000000000201006
Neurology, Vol. 99 (october 2022) , p. e1738-e1754
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7.
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12 p, 1.9 MB |
Sex-specific lesion pattern of functional outcomes after stroke
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Bonkhoff, Anna K. (J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Harvard Medical School) ;
Bretzner, Martin (Univ. Lille) ;
Hong, Sungmin (Massachusetts General Hospital (Boston)) ;
Schirmer, Markus D. (University Hospital Bonn (Bonn, Alemanya)) ;
Cohen, Alexander (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Regenhardt, Robert W. (Massachusetts General Hospital (Boston)) ;
Donahue, Kathleen L. (Massachusetts General Hospital (Boston)) ;
Nardin, Marco J. (Massachusetts General Hospital (Boston)) ;
Dalca, Adrian Vasile (Massachusetts General Hospital (Boston)) ;
Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ;
Etherton, Mark R. (Massachusetts General Hospital (Boston)) ;
Hancock, Brandon L. (Massachusetts General Hospital (Boston)) ;
Mocking, Steven J. T. (Massachusetts General Hospital (Boston)) ;
McIntosh, Elissa C. (Massachusetts General Hospital (Boston)) ;
Attia, John (University of Newcastle) ;
Benavente, Oscar R. (University of British Columbia) ;
Bevan, Stephen (University of Lincoln) ;
Cole, John W. (University of Maryland School of Medicine) ;
Donatti, Amanda (University of Campinas) ;
Griessenauer, Christoph J. (Paracelsus Medical University) ;
Heitsch, Laura (Washington University School) ;
Holmegaard, Lukas (Sahlgrenska University Hospital (Suècia)) ;
Jood, Katarina (Sahlgrenska University Hospital (Suècia)) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kittner, Steven J. (University of Maryland) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Levi, Christopher R. (John Hunter Hospital) ;
McDonough, Caitrin W. (University of Florida) ;
Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ;
Phuah, Chia-Ling (Washington University School of Medicine) ;
Rolfs, Arndt (Centogene AG) ;
Ropele, Stefan (Medical University Graz) ;
Rosand, Jonathan (Massachusetts General Hospital (Boston)) ;
Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rundek, Tatjana (University of Miami) ;
Sacco, Ralph L. (University of Miami. Miller School of Medicine) ;
Schmidt, Reinhold (Medical University Graz) ;
Sharma, Pankaj (St Peter's and Ashford Hospital) ;
Slowik, Agnieszka (Jagiellonian University Medical College) ;
Söderholm, Martin (Skåne University Hospital (Suècia)) ;
Sousa, Alessandro (University of Campinas) ;
Stanne, Tara M. (University of Gothenburg) ;
Strbian, Daniel (Helsinki University Hospital) ;
Tatlisumak, Turgut (Sahlgrenska Academy at University of Gothenburg) ;
Thijs, Vincent (Austin Health) ;
Vagal, Achala (University of Cincinnati College of Medicine) ;
Wasselius, Johan (Skåne University Hospital (Suècia)) ;
Woo, Daniel (University of Cincinnati College of Medicine) ;
Zand, Ramin (Department of Neurology, Geisinger) ;
McArdle, Patrick F. (University of Maryland School of Medicine) ;
Worrall, Bradford B. (University of Virginia) ;
Jern, Christina (Sahlgrenska University Hospital (Suècia)) ;
Lindgren, Arne G. (Lund University) ;
Maguire, Jane (University of Technology Sydney) ;
Fox, Michael D. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Bzdok, Danilo (Mila-Quebec Artificial Intelligence Institute) ;
Wu, Ona (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Rost, Natalia S. (Massachusetts General Hospital (Boston)) ;
Universitat Autònoma de Barcelona
Stroke represents a considerable burden of disease for both men and women. However, a growing body of literature suggests clinically relevant sex differences in the underlying causes, presentations and outcomes of acute ischaemic stroke. [...]
2022 - 10.1093/braincomms/fcac020
Brain Communications, Vol. 4 (february 2022)
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8.
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9 p, 990.5 KB |
International stroke genetics consortium recommendations for studies of genetics of stroke outcome and recovery
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Lindgren, Arne G. (Skåne University Hospital (Suècia)) ;
Braun, Robynne G. (Department of Neurology, University of Maryland) ;
Juhl Majersik, Jennifer (Department of Neurology, University of Utah) ;
Clatworthy, Philip (North Bristol NHS Trust) ;
Mainali, Shraddha (The Ohio State University) ;
Derdeyn, Colin P. (University of Iowa) ;
Maguire, Jane (University of Technology Sydney) ;
Jern, Christina (Sahlgrenska University Hospital (Suècia)) ;
Rosand, Jonathan (Massachusetts General Hospital (Boston)) ;
Cole, John W. (University of Maryland School of Medicine) ;
Lee, Jin-Moo (Washington University School of Medicine, St. Louis) ;
Khatri, Pooja (University of Cincinnati) ;
Nyquist, Paul (Johns Hopkins School of Medicine, Baltimore) ;
Debette, Stéphanie (Bordeaux University Hospital (França)) ;
Keat Wei, Loo (Universiti Tunku Abdul Rahman, Perak) ;
Rundek, Tatjana (University of Miami. Miller School of Medicine) ;
Leifer, Dana (Weill Cornell Medicine, New York) ;
Thijs, Vincent (Florey Institute of Neuroscience and Mental Health, Melbourne) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Heitsch, Laura (Washington University School of Medicine) ;
Prasad, Kameshwar (Rajendra Institute of Medical Sciences) ;
Jimenez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Dichgans, Martin (Institute for Stroke and Dementia Research (Munic, Alemanya)) ;
Rost, Natalia S. (Massachusetts General Hospital (Boston)) ;
Cramer, Steven C. (California Rehabilitation Institute) ;
Bernhardt, Julie (Florey Institute of Neuroscience and Mental Health (Melbourne, Austràlia)) ;
Worrall, Bradford B. (University of Virginia) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Numerous biological mechanisms contribute to outcome after stroke, including brain injury, inflammation, and repair mechanisms. Clinical genetic studies have the potential to discover biological mechanisms affecting stroke recovery in humans and identify intervention targets. [...]
2021 - 10.1177/17474930211007288
International Journal of Stroke, Vol. 17 (april 2021) , p. 260-268
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9.
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14 p, 3.0 MB |
Outcome after acute ischemic stroke is linked to sex-specific lesion patterns
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Bonkhoff, Anna K. (Massachusetts General Hospital (Boston)) ;
Schirmer, Markus D. (University Hospital Bonn (Bonn, Alemanya)) ;
Bretzner, Martin (Univ. Lille) ;
Hong, Sungmin (Massachusetts General Hospital (Boston)) ;
Regenhardt, Robert W. (Massachusetts General Hospital (Boston)) ;
Brudfors, Mikael (School of Biomedical Engineering & Imaging Sciences) ;
Donahue, Kathleen L. (Massachusetts General Hospital (Boston)) ;
Nardin, Marco J. (Massachusetts General Hospital (Boston)) ;
Dalca, Adrian Vasile (Massachusetts General Hospital (Boston)) ;
Giese, Anne-Katrin (University Medical Center Hamburg-Eppendorf) ;
Etherton, Mark R. (Massachusetts General Hospital (Boston)) ;
Hancock, Brandon L. (Massachusetts General Hospital (Boston)) ;
Mocking, Steven J. T. (Massachusetts General Hospital (Boston)) ;
McIntosh, Elissa C. (Massachusetts General Hospital (Boston)) ;
Attia, John (School of Medicine and Public Health) ;
Benavente, Oscar R. (University of British Columbia) ;
Bevan, Stephen (University of Lincoln) ;
Cole, John W. (University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System) ;
Donatti, Amanda (Brazilian Institute of Neuroscience and Neurotechnology (BRAINN)) ;
Griessenauer, Christoph J. (Research Institute of Neurointervention) ;
Heitsch, Laura (Washington University School of Medicine & Barnes-Jewish Hospital) ;
Holmegaard, Lukas (Sahlgrenska University Hospital (Suècia)) ;
Jood, Katarina (Sahlgrenska University Hospital (Suècia)) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kittner, Steven J. (University of Maryland School of Medicine and Veterans Affairs Maryland Health Care System) ;
Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ;
Levi, Christopher R. (John Hunter Hospital) ;
McDonough, Caitrin W. (University of Florida) ;
Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ;
Phuah, Chia-Ling (Washington University School of Medicine) ;
Rolfs, Arndt (Centogene AG) ;
Ropele, Stefan (Medical University Graz) ;
Rosand, Jonathan (Massachusetts General Hospital (Boston)) ;
Roquer, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rundek, Tatjana (University of Miami) ;
Sacco, Ralph L. (University of Miami) ;
Schmidt, Reinhold (Medical University Graz) ;
Sharma, Pankaj (St Peter's and Ashford Hospitals) ;
Slowik, Agnieszka (Jagiellonian University Medical College) ;
Söderholm, Martin (Skåne University Hospital (Suècia)) ;
Sousa, Alessandro (Brazilian Institute of Neuroscience and Neurotechnology (BRAINN)) ;
Stanne, Tara M. (the Sahlgrenska Academy at University of Gothenburg) ;
Strbian, Daniel (Helsinki University Hospital (Finlàndia)) ;
Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ;
Thijs, Vincent (Austin Health) ;
Vagal, Achala (University of Cincinnati College of Medicine) ;
Wasselius, Johan (Skåne University Hospital (Suècia)) ;
Woo, Daniel (University of Cincinnati College of Medicine) ;
Zand, Ramin (Geisinger) ;
McArdle, Patrick F. (University of Maryland School of Medicine) ;
Worrall, Bradford B. (University of Virginia) ;
Jern, Christina (Sahlgrenska University Hospital (Suècia)) ;
Lindgren, Arne G. (Lund University) ;
Maguire, Jane (University of Technology Sydney) ;
Bzdok, Danilo (Mila - Quebec Artificial Intelligence Institute) ;
Wu, Ona (Massachusetts General Hospital (Boston)) ;
Rost, Natalia S. (Massachusetts General Hospital (Boston)) ;
Universitat Autònoma de Barcelona
Acute ischemic stroke affects men and women differently. In particular, women are often reported to experience higher acute stroke severity than men. We derived a low-dimensional representation of anatomical stroke lesions and designed a Bayesian hierarchical modeling framework tailored to estimate possible sex differences in lesion patterns linked to acute stroke severity (National Institute of Health Stroke Scale). [...]
2021 - 10.1038/s41467-021-23492-3
Nature communications, Vol. 12 (june 2021)
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10.
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26 p, 1.4 MB |
The copy number variation and stroke (CaNVAS) risk and outcome study
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Cole, John W. (University of Maryland School of Medicine) ;
Adigun, Taiwo (University of Ibadan) ;
Akinyemi, Rufus (University of Ibadan) ;
Akpa, Onoja Matthew (University of Ibadan) ;
Bell, Steven (Unversity of Cambridge) ;
Chen, Bowang (National Center for Cardiovascular Diseases, Beijing) ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lazcano, Uxue (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Fornage, Myriam (University of Texas Health Science at Houston) ;
Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Jern, Christina (University of Gothenburg) ;
Krawczak, Michael (University of Kiel) ;
Lindgren, Arne (Neurology, Lund University) ;
Markus, Hugh S. (Unversity of Cambridge) ;
Melander, Olle (Neurology, Lund University) ;
Owolabi, Mayowa (University of Ibadan) ;
Schlicht, Kristina (University of Kiel) ;
Söderholm, Martin (Skåne University Hospital (Suècia)) ;
Srinivasasainagendra, Vinodh (University of Alabama at Birmingham) ;
Soriano Tárraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Stenman, Martin (Lund University) ;
Tiwari, Hemant (University of Alabama at Birmingham) ;
Corasaniti, Margaret (University of Maryland School of Medicine) ;
Fecteau, Natalie (University of Maryland School of Medicine) ;
Guizzardi, Beth (University of Maryland School of Medicine) ;
Lopez, Haley (University of Maryland School of Medicine) ;
Nguyen, Kevin (University of Maryland School of Medicine) ;
Gaynor, Brady (University of Maryland School of Medicine) ;
O'Connor, Timothy (University of Maryland School of Medicine) ;
Stine, O. Colin (University of Maryland School of Medicine) ;
Kittner, Steven J. (University of Maryland School of Medicine) ;
McArdle, Patrick (University of Maryland School of Medicine) ;
Mitchell, Braxton D. (University of Maryland School of Medicine) ;
Xu, Huichun (University of Maryland School of Medicine) ;
Grond-Ginsbach, Caspar (Heidelberg University) ;
Universitat Autònoma de Barcelona
The role of copy number variation (CNV) variation in stroke susceptibility and outcome has yet to be explored. The Copy Number Variation and Stroke (CaNVAS) Risk and Outcome study addresses this knowledge gap. [...]
2021 - 10.1371/journal.pone.0248791
PloS one, Vol. 16 (april 2021)
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