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1.
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12 p, 2.8 MB |
Are bioplastics safe? : Hazardous effects of polylactic acid (PLA) nanoplastics in Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Farre, Marinella (Institut de Diagnosi Ambiental i Estudis de l'Aigua) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The expanded uses of bioplastics require understanding the potential health risks associated with their exposure. To address this issue, Drosophila melanogaster as a versatile terrestrial in vivo model was employed, and polylactic acid nanoplastics (PLA-NPLs), as a proxy for bioplastics, were tested as a material model. [...]
2024 -  10.1016/j.scitotenv.2024.170592
Science of the total environment, Vol. 919 (April 2024) , art. 170592
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2.
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14 p, 7.3 MB |
Alcohol-free synthesis, biological assessment, in vivo toxicological evaluation, and in silico analysis of novel silane quaternary ammonium compounds differing in structure and chain length as promising disinfectants
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Tagorti, Ghada (Akdeniz University. Department of Biology) ;
Yalçın, Burçin (Akdeniz University. Department of Biology) ;
Güneş, Merve (Akdeniz University. Department of Biology) ;
Burgazlı, Ayşen Yağmur (Akdeniz University. Department of Biology) ;
Kuruca, Tuğçe (Akdeniz University. Department of Chemistry) ;
Cihanoğlu, Neslihan (Akdeniz University. Department of Chemistry) ;
Akarsu, Esin (Akdeniz University. Department of Chemistry) ;
Kaya, Nuray (Akdeniz University. Department of Biology) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Kaya, Bülent (Akdeniz University. Department of Biology)
Quaternary ammonium compounds (QACs) are commonly used as disinfectants for industrial, medical, and residential applications. However, adverse health outcomes have been reported. Therefore, biocompatible disinfectants must be developed to reduce these adverse effects. [...]
2024 - 10.1016/j.jhazmat.2024.133470
Journal of hazardous materials, Vol. 466 (March 2024) , art. 133470
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3.
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11 p, 771.0 KB |
Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?
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Cabrera Serrano, Antonio José (Instituto de Investigación Sanitaria de Granada) ;
Sánchez Maldonado, José Manuel (Instituto de Investigación Sanitaria de Granada) ;
ter Horst, Rob (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) ;
Macauda, Angelica (German Cancer Research Center) ;
García Martín, Paloma (Hospital Campus de la Salud (Granada)) ;
Benavente, Yolanda (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Landi, Stefano (Department of Biology. University of Pisa) ;
Clay-Gilmour, Alyssa (Department of Epidemiology & Biostatistics. Arnold School of Public Health. University of South Carolina) ;
Niazi, Yasmeen (Hopp Children's Cancer Center) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez-Sevilla, Juan Jose (Department of Leukemia. The University of Texas MD Anderson Cancer Center) ;
Pérez, Eva María (Hospital Campus de la Salud) ;
Maffei, Rossana (University of Modena and Reggio Emilia) ;
Blanco, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giaccherini, Matteo (Department of Biology. University of Pisa) ;
Cerhan, James R. (Department of Quantitative Health Sciences. Mayo Clinic) ;
Marasca, Roberto (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia. AOU Policlinico) ;
Lopez Nevot, Miguel Angel (Hospital Universitario Virgen de las Nieves (Granada)) ;
Chen-Liang, Tzu Hua (Hospital Universitario Morales Meseguer (Múrcia)) ;
Thomsen, Hauke (MSB Medical School Berlin) ;
Gámez, Irene (Hematology Department. Morales Meseguer University Hospital) ;
Campa, Daniele (Department of Biology. University of Pisa) ;
Moreno Aguado, Víctor (Facultat de Medicina. Universitat de Barcelona) ;
de Sanjosé, Silvia (Universitat de Barcelona) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Álvarez, María Flor (Instituto de Investigación Biomédica de Salamanca) ;
Dierssen-Sotos, Trinidad (Universidad de Cantabria) ;
Jerez, Andrés (Vall d'Hebron Institut d'Oncologia) ;
Butrym, Aleksandra (Department of Cancer Prevention and Therapy. Medical University of Wrocław) ;
Norman, Aaron D. (Department of Quantitative Health Sciences. Mayo Clinic) ;
Luppi, Mario (University of Modena and Reggio Emilia) ;
Slager, Susan L. (Mayo Clinic) ;
Hemminki, Kari (Charles University in Prague) ;
Li, Yang (Hannover Medical School) ;
Berndt, Sonja I. (National Institutes of Health (Estats Units d'Amèrica)) ;
Casabonne, Delphine (Universitat de Barcelona) ;
Alcoceba, Miguel (Instituto de Investigación Biomédica de Salamanca) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Netea, Mihai G. (Department for Immunology & Metabolism. University of Bonn) ;
Försti, Asta (Hopp Children's Cancer Center) ;
Canzian, Federico (German Cancer Research Center) ;
Sainz, Juan (Department of Biochemistry and Molecular Biology. Universidad de Granada)
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults worldwide. Although genome-wide association studies (GWAS) have uncovered the germline genetic component underlying CLL susceptibility, the potential use of GWAS-identified risk variants to predict disease progression and patient survival remains unexplored. [...]
2023 - 10.3390/ijms24098005
International journal of molecular sciences, Vol. 24 Núm. 9 (may 2023) , p. 8005
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4.
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8 p, 715.4 KB |
Head and neck cancers survival in Europe, Taiwan, and Japan : results from RARECAREnet Asia based on a privacy-preserving federated infrastructure
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Botta, Laura (Department of Epidemiology and Data Science. Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Matsuda, Tomohiro (Insititute of Cancer Control. National Cancer Center (Japò)) ;
Charvat, Hadrien (National Cancer Center (Japò)) ;
Chiang, Chung-Ju (Taiwan Cancer Registry Center) ;
Lee, Wen-Chung (Taiwan Cancer Registry Center) ;
van Gestel, Anna Jacoba (Department of Research & Development. Netherlands Comprehensive Cancer Organisation) ;
Martin, Frank (Department of Research & Development. Netherlands Comprehensive Cancer Organisation) ;
Geleijnse, Gijs (Department of Research & Development. Netherlands Comprehensive Cancer Organisation) ;
Cellamare, Mattheo (Department of Research & Development. Netherlands Comprehensive Cancer Organisation) ;
Bonfarnuzzo, Simone (Department of Epidemiology and Data Science. Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Guevara, Marcela (Instituto de Investigación Sanitaria de Navarra) ;
Mousavi, Mohsen (East Switzerland Cancer Registry) ;
Craig, Stefano (Queen's University Belfast) ;
Rodrigues, Jessica (Porto Comprehensive Cancer Centre (Portugal)) ;
Rubió-Casadevall, Jordi (Institut de Recerca Biomèdica de Lleida) ;
Licitra, Lisa (Department of Oncology and Hemato-Oncology. University of Milan) ;
Cavalieri, Stephanie (Department of Oncology and Hemato-Oncology. University of Milan) ;
Resteghini, Carlo (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano) ;
Gatta, Gemma (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano) ;
Trama, Annalisa (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano)
Background: The head and neck cancers (HNCs) incidence differs between Europe and East Asia. Our objective was to determine whether survival of HNC also differs between European and Asian countries. [...]
2023 - 10.3389/fonc.2023.1219111
Frontiers in Oncology, Vol. 13 (2023) , p. 1219111
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5.
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12 p, 1019.0 KB |
Incidence and time trends of childhood hematological neoplasms : a 36-year population-based study in the southern European context, 1983-2018
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Trallero, Jan (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Almela Vich, Fernando (Valencian Community Department of Universal Health and Public Health) ;
Jeghalef El Karoni, Noura (Valencian Community Department of Universal Health and Public Health) ;
Saez Lloret, Isabel (Valencian Community Department of Universal Health and Public Health) ;
Díaz-del-Campo, Cristina (Health and Social Welfare Authority, Ciudad Real) ;
Marcos-Navarro, Ana Isabel (Health and Social Welfare Authority, Cuenca) ;
Aizpurua Atxega, Amaia (Basque Country Cancer Registry, Basque Government, Vitoria-Gasteiz) ;
Sancho Uriarte, Patricia (Basque Country Cancer Registry, Basque Government, Vitoria-Gasteiz) ;
De-la-Cruz Ortega, Marta (Basque Country Cancer Registry, Basque Government, Vitoria-Gasteiz) ;
Sánchez, María José (University of Granada) ;
Perucha, Josefina (Epidemiology and Health Prevention Service, Logroño) ;
Franch, Paula (Institut d'Investigació Sanitària Illes Balears) ;
Chirlaque, María Dolores (Instituto Murciano de Investigación Biosanitaria (IMIB)-Arrixaca) ;
Guevara, Marcela (Instituto de Salud Pública de Navarra) ;
Ameijide, Alberto (Institut d'Investigació Sanitària Pere Virgili) ;
Galceran, Jaume (Institut d'Investigació Sanitària Pere Virgili) ;
Ramírez, Cristina (Health and Social Welfare Authority, Albacete) ;
Rodríguez Camblor, Marta (Asturias Cancer Registry, Public Health Directorate) ;
Alemán, Maria Araceli (Public Health Directorate, Tenerife) ;
Gutiérrez, Pilar (Public Health Directorate, Valladolid) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Background: Hematological neoplasms (HNs) are the first and most common childhood cancers globally. Currently, there is a lack of updated population-based data on the incidence of these cancers in the Spanish pediatric population. [...]
2023 - 10.3389/fonc.2023.1197850
Frontiers in Oncology, Vol. 13 (july 2023)
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6.
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32 p, 5.0 MB |
Childhood and Adolescent Central Nervous System Tumours in Spain : Incidence and Survival over 20 Years: A Historical Baseline for Current Assessment
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Chirlaque, María D. (Universidad de Murcia. Departamento de Epidemiología) ;
Peris-Bonet, Rafael (Spanish Registry of Childhood Tumours. University of Valencia) ;
Sánchez, Antonia (Department of Epidemiology. Murcia Regional Health Authority) ;
Cruz, Ofelia (Hospital Sant Joan de Déu (Manresa)) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gutiérrez-Ávila, Gonzalo (Castile-La Mancha Cancer Registry) ;
Quirós-García, José R. (Asturias Cancer Registry. Public Health Directorate) ;
Almela-Vich, Fernando (Valencian Regional Childhood Cancer Registry) ;
López de Munain, Arantza (Basque Country Cancer Registry) ;
Sánchez, María J. (Granada Bio-Health Research Institute) ;
Franch-Sureda, Paula (Mallorca Cancer Registry. Balearic Isles Health Research Institute) ;
Ardanaz, Eva (Navarre Health Research Institute) ;
Galceran, Jaume (Universitat Rovira i Virgili) ;
Martos, Carmen (Foundation for the Promotion of Health and Biomedical Research in the Valencian Region) ;
Salmerón, Diego (Universidad de Murcia. Department of Health and Social Sciences) ;
Gatta, Gemma (Fondazione IRCCS Istituto Nazionale dei Tumori di Milano) ;
Botta, Laura (Istituto Nazionale dei Tumori) ;
Cañete, Adela (Universitat de València)
Background: Central nervous system (CNS) neoplasms are highly frequent solid tumours in children and adolescents. While some studies have shown a rise in their incidence in Europe, others have not. Survival remains limited. [...]
2023 - 10.3390/cancers15245889
Cancers, Vol. 15 Núm. 24 (december 2023) , p. 5889
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7.
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11 p, 310.2 KB |
Time trends and survival of marginal zone lymphoma over 25 years in Girona, Spain (1994-2018)
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Auñón, Carmen (Universitat de Girona. Departament de Medicina) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Turon, Estel (Institut d'Investigació Biomèdica de Girona) ;
Vidal Vila, Anna (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Puigdemont, Montse (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Osca Gelis, Gemma (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Eraso, Arantxa (Universitat de Girona. Departament de Medicina) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Objective: To analyze the incidence, incidence trends, and survival of marginal zone lymphomas (MZLs) in Girona and to describe these indicators based on the location in the case of extranodal MZLs. Methods: Population-based study of MZL collected in the Girona Cancer Registry, 1994-2018. [...]
2023 - 10.1002/cam4.5935
Cancer Medicine, Vol. 12 Núm. 11 (june 2023) , p. 12343-12353
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8.
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12 p, 7.1 MB |
The release of polylactic acid nanoplastics (PLA-NPLs) from commercial teabags : Obtention, characterization, and hazard effects of true-to-life PLA-NPLs
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Banaei, Gooya (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
García-Rodríguez, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Tavakolpournegari, Alireza (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Martín-Pérez, Juan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
This study investigates MNPLs release from commercially available teabags and their effects on both undifferentiated monocultures of Caco-2 and HT29 and in the in vitro model of the intestinal Caco-2/HT29 barrier. [...]
2023 - 10.1016/j.jhazmat.2023.131899
Journal of hazardous materials, Vol. 458 (September 2023) , art. 131899
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9.
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10 p, 5.0 MB |
Titanium-doped PET nanoplastics, from opaque milk bottle degradation, as a model of environmental true-to-life nanoplastics. Hazardous effects on Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Micro and nanoplastics (MNPLs) are emergent environmental pollutants, resulting from the degradation of plastic waste, requiring urgent information on their potential risks to human health. To determine such risks, reliable true-to-life materials are essential. [...]
2024 - 10.1016/j.envpol.2023.122968
Environmental Pollution, Vol. 341 (January 2024) , art. 122968
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10.
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14 p, 1.6 MB |
Toxicological Profiling and Long-Term Effects of Bare, PEGylated- and Galacto-Oligosaccharide-Functionalized Mesoporous Silica Nanoparticles
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Barguilla, Irene (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Candela-Noguera, Vicente (Universitat Politècnica de València) ;
Oliver, Patrick (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Annangi, Balasubramanyam (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Díez, Paula (Universitat Politècnica de València) ;
Aznar, Elena (Universitat Politècnica de València) ;
Martínez-Máñez, Ramón (Universitat Politècnica de València) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Martínez, Maria Dolores (Universitat Politècnica de València)
Mesoporous silica nanoparticles (MSNs) are amongst the most used nanoparticles in biomedicine. However, the potentially toxic effects of MSNs have not yet been fully evaluated, being a controversial matter in research. [...]
2023 - 10.3390/ijms242216158
International journal of molecular sciences, Vol. 24, Issue 22 (November 2023) , art. 16158
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