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Resultats globals: 5 registres trobats en 0.01 segons.
Articles, 5 registres trobats
Articles 5 registres trobats  
1.
9 p, 1.4 MB Predictive signature of response to neoadjuvant chemotherapy in muscle-invasive bladder cancer integrating mRNA expression, taxonomic subtypes, and clinicopathological features / Font, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domenech, Montserrat (Althaia Xarxa Assistencial Universitària de Manresa) ; Ramirez, Jose Luis (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Marqués, Miriam (Centro Nacional de Investigaciones Oncológicas) ; Benítez, Raquel (Centro Nacional de Investigaciones Oncológicas) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gago, José L. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Carrato, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sant, Francesc (Althaia Xarxa Assistencial Universitària de Manresa) ; Lopez, Hector (Althaia Xarxa Assistencial Universitària de Manresa) ; Castellano, Daniel (Hospital Universitario 12 de Octubre (Madrid)) ; Malats, Núria (Centro Nacional de Investigaciones Oncológicas) ; Calle, M. Luz (Universitat de Vic - Universitat Central de Catalunya) ; Real, Francisco X. (Universitat Pompeu Fabra)
Background and objective: Neoadjuvant chemotherapy (NAC) followed by cystectomy is the standard of care in muscle-invasive bladder cancer (MIBC). Pathological response has been associated with longer survival, but no currently available clinicopathological variables can identify patients likely to respond, highlighting the need for predictive biomarkers. [...]
2023 - 10.3389/fonc.2023.1155244
Frontiers in Oncology, Vol. 13 (august 2023)  
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2.
29 p, 1.4 MB Lipid Metabolism and Epigenetics Crosstalk in Prostate Cancer / Pardo, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gil, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Font, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ; Jordà, Mireia (Institut Germans Trias i Pujol)
Prostate cancer (PCa) is the most commonly diagnosed malignant neoplasm in men in the Western world. Localized low-risk PCa has an excellent prognosis thanks to effective local treatments; however, despite the incorporation of new therapeutic strategies, metastatic PCa remains incurable mainly due to disease heterogeneity and the development of resistance to therapy. [...]
2022 - 10.3390/nu14040851
Nutrients, Vol. 14 Núm. 4 (february 2022) , p. 851  
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3.
17 p, 2.4 MB Tumor expression of cyclin-dependent kinase 5 (Cdk5) is a prognostic biomarker and predicts outcome of oxaliplatin-treated metastatic colorectal cancer patients / Ruiz de Porras, V. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Cabrero de las Heras, Sara (Institut Germans Trias i Pujol) ; Musulén, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Palomero, L. (Institut d'Investigació Biomèdica de Bellvitge) ; Alonso, M. H. (Universitat de Barcelona. Departament de Ciències Clíniques) ; Nieto Raya, Rocio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Moreno, V. (Universitat de Barcelona. Departament de Ciències Clíniques) ; Queralt, C. (Institut Germans Trias i Pujol) ; Manzano Mozo, José Luís (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
In recent years, an increasing number of studies have shown that elevated expression of cyclin dependent kinase (Cdk5) contributes to the oncogenic initiation and progression of many types of cancers. [...]
2019 - 10.3390/cancers11101540
Cancers, Vol. 11 Núm. 10 (october 2019) , p. 1540  
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4.
17 p, 2.9 MB Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway / Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Howells, Lynne (University of Leicester. Departament of Cancer Studies) ; James, Mark I. (University of Leicester. Departament of Cancer Studies) ; Iwuji, Chinenye (University of Leicester. Departament of Cancer Studies) ; Manzano, José Luis (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Abad, Albert (Hospital Cima Sanitas (Barcelona)) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol)
Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. [...]
2016 - 10.1038/srep24675
Scientific reports, Vol. 6 (April 2016)  
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5.
20 p, 10.3 MB PKM2 subcellular localization is involved in oxaliplatin resistance acquisition in HT29 human colorectal cancer cell lines / Ginés Molina, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guardia, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Musulén, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Manzano, José Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Abad, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Chemoresistance is the main cause of treatment failure in advanced colorectal cancer (CRC). However, molecular mechanisms underlying this phenomenon remain to be elucidated. In a previous work we identified low levels of PKM2 as a putative oxaliplatin-resistance marker in HT29 CRC cell lines and also in patients. [...]
2015 - 10.1371/journal.pone.0123830
PloS one, Vol. 10, No. 5 (May 2015) , p. e0123830  
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