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8 p, 608.6 KB |
Medical Students' Opinion of Their Learning Process
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Montané Esteva, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Riera, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pujol, Marina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Méndez Hernández, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mas, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vara, Angel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Parés, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
The opinion of students is of utmost importance to identify areas of improvement in undergraduate studies. Medical schools would use this information to plan actions to ensure that the students achieve the necessary medical knowledge. [...]
2023 -  10.1007/s40670-023-01873-1
Medical Science Educator, Vol. 33 (september 2023) , p. 1183-1190
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2.
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8 p, 915.7 KB |
Disseminated tuberculosis and diagnosis delay during the COVID-19 era in a Western European country : a case series analysis
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Roure, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vallès, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sopena, Nieves (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Benítez Díaz, Rosa María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Reynaga, Esteban (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bracke Manzanares, Carmen (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Loste, Cora (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mateu, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Antuori Torres, Adrián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Baena, Tania (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Portela, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Llussà, Judith (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Flamarich, Clara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Soldevila, Laura (Direcció Clínica Territorial de Malalties Infeccioses i Salut Internacional de Gerència Territorial Metropolitana Nord) ;
Tenesa, Montserrat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Plasencia, Elsa (Subdirecció General de Vigilancia i Resposta a Emergències de Salut Pública) ;
Bechini Bernad, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pedro-Botet, Maria Lluïsa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Disseminated tuberculosis is frequently associated with delayed diagnosis and a poorer prognosis. To describe case series of disseminated TB and diagnosis delay in a low TB burden country during the COVID-19 period. [...]
2023 - 10.3389/fpubh.2023.1175482
Frontiers in Public Health, Vol. 11 (may 2023)
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2 p, 73.0 KB |
Corrigendum : Disseminated tuberculosis and diagnosis delay during the COVID-19 era in a Western European country: a case series analysis
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Roure, Silvia (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Vallès, Xavier (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Sopena, Nieves (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Benítez Díaz, Rosa María (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Reynaga, Esteban (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Bracke Manzanares, Carmen (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Loste, Cora (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Mateu, Lourdes (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Antuori Torres, Adrián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Baena, Tania (Institut Germans Trias i Pujol. Fundació Lluita Contra les Infeccions) ;
Portela, Germán (Institut Català de la Salut) ;
Llussà, Judith (Institut Català de la Salut) ;
Flamarich, Clara (Institut Català de la Salut) ;
Soldevila, Laura (Direcció Clínica Territorial de Malalties Infeccioses i Salut Internacional de Gerència Territorial Metropolitana Nord) ;
Tenesa, Montserrat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Plasencia, Elsa (Subdirecció General de Vigilancia i Resposta a Emergències de Salut Pública) ;
Bechini Bernad, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pedro-Botet, Maria Lluïsa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Disseminated tuberculosis is frequently associated with delayed diagnosis and a poorer prognosis. To describe case series of disseminated TB and diagnosis delay in a low TB burden country during the COVID-19 period. [...]
2023 - 10.3389/fpubh.2023.1236874
Frontiers in Public Health, Vol. 11 (june 2023)
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14 p, 690.6 KB |
The role of antibodies in tuberculosis diagnosis, prophylaxis and therapy : a review from the ESGMYC study group
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Melkie, Solomon Tibebu (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Arias, Lilibeth (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Farroni, Chiara (National Institute for Infectious Diseases-IRCCS L. Spallanzani) ;
Jankovic Makek, Mateja (University Clinical Centre Zagreb) ;
Goletti, Delia (National Institute for Infectious Diseases-IRCCS L. Spallanzani) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Tuberculosis (TB) is still responsible for the deaths of >1 million people yearly worldwide, and therefore its correct diagnosis is one of the key components of any TB eradication programme. However, current TB diagnostic tests have many limitations, and improved diagnostic accuracy is urgently needed. [...]
2022 - 10.1183/16000617.0218-2021
European Respiratory Review, Vol. 31 (march 2022)
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22 p, 4.7 MB |
Macrophage CD5L is a target for cancer immunotherapy
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Sanchez-Moral, Lidia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Paul, Tony (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martori Muntsant, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Font-Díaz, Joan (Universitat de Barcelona) ;
Sanjurjo, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Aran, Gemma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Téllez, Érica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ito, Masaoki (Hiroshima University) ;
Tuttolomondo, Martina (University of Southern Denmark) ;
Ditzel, Henrik J. (Odense University Hospital (Dinamarca)) ;
Fumagalli, Caterina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Tapia, Gustavo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sidorova, Julia (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fernández-Sanmartín, Marco-Antonio (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Lozano, Juan-José (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodriguez-Cortes, Alheli (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Armengol, Carolina (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Valledor, Annabel F. (Universitat de Barcelona) ;
Kremer, Leonor (Centro Nacional de Biotecnología (Espanya)) ;
Sarrias, Maria-Rosa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Reprogramming of immunosuppressive tumor-associated macrophages (TAMs) presents an attractive therapeutic strategy in cancer. The aim of this study was to explore the role of macrophage CD5L protein in TAM activity and assess its potential as a therapeutic target. [...]
2023 - 10.1016/j.ebiom.2023.104555
EBioMedicine, Vol. 91 (april 2023)
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28 p, 4.0 MB |
Mycobacterium manresensis induces trained immunity in vitro
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de Homdedeu, Miquel (Hospital Universitari Vall d'Hebron) ;
Sanchez-Moral, Lidia (Institut Germans Trias i Pujol) ;
Violán, Concepció (Universitat Autònoma de Barcelona) ;
Ràfols, Neus (Institut Germans Trias i Pujol) ;
Ouchi, Dan (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Martín, Berta (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Peinado, Miguel A. (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ;
Rodriguez-Cortes, Alheli (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Arch Sisquella, Marta (Institut Germans Trias i Pujol) ;
Perez-Zsolt, Daniel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Muñoz-Basagoiti, Jordana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Izquierdo Useros, Nuria (Centre for Biomedical Research on Infectious Diseases) ;
Salvador, Betlem (Jordi Gol University Research Institute in Primary Care) ;
Matllo, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López-Serrano, Sergi (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Vilaplana, Cristina (Direcció Clínica Territorial de Malalties Infeccioses i Salut Internacional de Gerència Territorial Metropolitana Nord) ;
Torán-Montserrat, Pere (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Morros, Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Monfà, Ramon (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Sarrias, Maria-Rosa (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cardona, Pere-Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
The COVID-19 pandemic posed a global health crisis, with new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants weakening vaccine-driven protection. Trained immunity could help tackle COVID-19 disease. [...]
2023 - 10.1016/j.isci.2023.106873
iScience, Vol. 26 (may 2023) , p. 106873
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21 p, 6.8 MB |
Surveillance of Daughter Micronodule Formation Is a Key Factor for Vaccine Evaluation Using Experimental Infection Models of Tuberculosis in Macaques
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Nogueira, Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Català, Martí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
White, Andrew D. (National Infection Service (Salisbury, Regne Unit)) ;
Sharpe, Sally A. (National Infection Service (Salisbury, Regne Unit)) ;
Bechini Bernad, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prats, Clara (Universitat Politècnica de Catalunya. Departament de Física) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cardona, Pere-Joan (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Tuberculosis (TB) is still a major worldwide health problem and models using non-human primates (NHP) provide the most relevant approach for vaccine testing. In this study, we analysed CT images collected from cynomolgus and rhesus macaques following exposure to ultra-low dose Mycobacterium tuberculosis (Mtb) aerosols, and monitored them for 16 weeks to evaluate the impact of prior intradermal or inhaled BCG vaccination on the progression of lung disease. [...]
2023 - 10.3390/pathogens12020236
Pathogens, Vol. 12 (february 2023)
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11 p, 3.1 MB |
Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections
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Moreno-Molina, Miguel (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Shubladze, Natalia (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Khurtsilava, Iza (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Avaliani, Zaza (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Bablishvili, Nino (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Torres-Puente, Manuela (Instituto de Biomedicina de Valencia (IBV-CSIC)) ;
Villamayor, Luis (FISABIO Public Health) ;
Gabrielian, Andrei (National Institutes of Health. Department of Health and Human Services (Estats Units d'Amèrica)) ;
Rosenthal, Alex (National Institutes of Health. Department of Health and Human Services (Estats Units d'Amèrica)) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gagneux, Sebastien (University of Basel) ;
Kempker, Russell R. (Emory University School of Medicine. Department of Medicine) ;
Vashakidze, Sergo (National Center for Tuberculosis and Lung Diseases of Georgia) ;
Comas, I (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Universitat Autònoma de Barcelona
Polyclonal infections occur when at least two unrelated strains of the same pathogen are detected in an individual. This has been linked to worse clinical outcomes in tuberculosis, as undetected strains with different antibiotic resistance profiles can lead to treatment failure. [...]
2021 - 10.1038/s41467-021-22705-z
Nature communications, Vol. 12 (may 2021)
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5 p, 449.3 KB |
Prophylactic Effect of a Therapeutic Vaccine against TB Based on Fragments of Mycobacterium tuberculosis
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Vilaplana, Cristina (Institut Germans Trias i Pujol) ;
Gil, Olga (Institut Germans Trias i Pujol) ;
Cáceres, Neus (Institut Germans Trias i Pujol) ;
Pinto, Sergio (Institut Germans Trias i Pujol) ;
Díaz, Jorge (Institut Germans Trias i Pujol) ;
Cardona, Pere-Joan (Institut Germans Trias i Pujol)
The prophylactic capacity of the RUTI® vaccine, based on fragmented cells of Mycobacterium tuberculosis, has been evaluated in respect to aerosol challenge with virulent bacilli. Subcutaneous vaccination significantly reduced viable bacterial counts in both lungs and spleens of C57Bl mice, when challenged 4 weeks after vaccination. [...]
2011 - 10.1371/journal.pone.0020404
PloS one, Vol. 6 (may 2011)
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