Publications last 10 years
Publications 2021
Elia Santigosa-Murillo, Santiago Maspoch, Maria Muñoz, Maria Ramos-Payán. An efficient microfluidic device based on electromembrane extraction for the simultaneous extraction of acidic and basic drugs. Analytica Chimica Acta 1160 (2021) 338448
Publications 2020
Putthiporn Khongkaew, Chutima Phechkrajang, Jordi Cruz, Vanessa Cárdenas Piyanunuch Rojsanga. Quantitative models for detecting the presence of lead in turmeric using Raman spectrsocopy. Chemometrics and Intelligent Laboratory Systems 2020, 200:103994
Elia Santigosa-Murillo, Xavier Muñoz-Berbel, Santiago Maspoch, Maria Muñoz, Maria Ramos-Payan. Impedance model for voltage optimization of parabens extraction in an electromembrane milifluidic device. Journal of Chromatography A 2020, 1625: 461270
Gloria Clua-Palau, Enric Jo, Sasha Nikolic, Jordi Coello, Santiago Maspoch. Finding a reliable lmit of detection in the NIR determination of residual moisture in a freeze-dried . Journal of Pharmaceutical and Biomedical Analysis 2020, 183: 113163-113170
César Pino-Torres, Santiago Maspoch, Rosario Castillo-Felices, Mónica Pérez-Rivera, Mario Aranda-Bustos. Carloes Peña-Farfal, Evaluation of NIR and Raman spectroscopies for the quality analyticalcontrol of a solid pharmaceutical formulation with three active ingredients. Microchemical Journal 2020,154:104576-
Publications 2019
J. Ricardo Lucio-Gutiérrez, Cecilia Delgado-Montemayor, Jordi Coello Bonilla, Noemí Waksman-Minsky, Alma L. Saucedo Selective 1D-TOCSY and chemometrics t evaluate authenticity of Turnera Diffusa and related botanical extracts. Phytochemistry Letters 2019,30:62-68
J. Puig-Bertotto, J. Coello, S.Maspoch Evaluation of a handheld near-infrared spectrophotometer for quantitative determination of two APIs in a solid pharmaceutical preparation Analytical Methods, 2019, 11 : 327-335
Elia Santigosa, Santiago Maspoch, Maria Ramos Payán, Liquid phase microextraction integrated into a microchip devise for the extraction of fluoroquinolones from urine samples. Microchemical Journal 2019, 145: 280-286
Diego A. Gómez, Jordi Coello, Santiago Maspoch, The influence of particle size on the intensity and reproducibility of Raman spectra of compacted samples, Vibrational Spectroscopy 2019,100: 48-56
Publications 2018
Ivaylo Stefanov, Dolores Hinojosa-Caballero, Santiago Maspoch, Javier Hoyo, Tzanko Tzanov, Enzymatic synthesis of a thiolated chitosan-based wound dressing crosslinked with chicoric acid. Journal of Material Chemistry B, 2018. 6: 7943-7953
Maria Ramos Payan, Elia Santigosa Murillo, Jordi Coello, Miguel Angel Bello López. A comprehensive study of a new versatile microship device based liquid phase microextaction for stopped-flow and double-flow conditions. Journal of Chromatography A, 2018, 1556:29-36
Publications 2017
Ramos-Payán M, Ocaña-González JA, Fernández-Torres RM, Maspoch S, Bello-López MÁ. Recent advances in sample pre-treatment for emerging methods in proteomic analysis. Talanta 2017;174:738-751.
Ramos-Payan M, Maspoch S, Llobera A. A simple and fast Double-Flow microfluidic device based liquid-phase microextraction (DF-µLPME) for the determination of parabens in water samples. Talanta 2017;165:496-501.
Palou A, Miró A, Blanco M, Larraz R, Gómez JF, Martínez T, et al. Calibration sets selection strategy for the construction of robust PLS models for prediction of biodiesel/diesel blends physico-chemical properties using NIR spectroscopy. Spectrochim Acta Part A Mol Biomol Spectrosc 2017;180:119-126.
Li C, Wang F, Zang L, Zang H, Alcalà M, Nie L, et al. Near infrared spectroscopy combined with multivariate analysis for monitoring the ethanol precipitation process of fraction I + II + III supernatant in human albumin separation. Spectrochim Acta Part A Mol Biomol Spectrosc 2017;175:17-23.
Wang J, Li T, Yang H, Hu T, Nie L, Wang F, et al. Geographical origin discrimination and polysaccharides quantitative analysis of radix codonopsis with micro near-infrared spectrometer engine. J Innovative Opt Health Sci 2017.
Publications 2016
Ramos-Payan M, Maspoch S, Llobera A. An effective microfluidic based liquid-phase microextraction device (μLPME) for extraction of non-steroidal anti-inflammatory drugs from biological and environmental samples. Anal Chim Acta 2016;946:56-63.
Gómez DA, Coello J, Maspoch S. Raman spectroscopy for the analytical quality control of low-dose break-scored tablets. J Pharm Biomed Anal 2016;124:207-215.
Romanãch RJ, Román-Ospino AD, Alcalà M. A procedure for developing quantitative near infrared (NIR) methods for pharmaceutical products. Methods Pharmacol Toxicol 2016;32:133-158.
Publications 2015
Cárdenas V, Cordobés M, Blanco M, Alcalà M. Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology. J Pharm Biomed Anal 2015;114:28-33.
Armenta S, Garrigues S, de la Guardia M, Brassier J, Alcalà M, Blanco M, et al. Detection and characterization of emerging psychoactive substances by ion mobility spectrometry. Drug Test Anal 2015;7(4):280-289.
Armenta S, Garrigues S, de la Guardia M, Brassier J, Alcalà M, Blanco M. Analysis of ecstasy in oral fluid by ion mobility spectrometry and infrared spectroscopy after liquid-liquid extraction. J Chromatogr A 2015;1384:1-8.
Publications 2014
Armenta S, De La Guardia M, Alcalà M, Blanco M, Perez-Alfonso C, Galipienso N. Ion mobility spectrometry evaluation of cocaine occupational exposure in forensic laboratories. Talanta 2014;130:251-258.
Rosas JG, de Waard H, De Beer T, Vervaet C, Remon JP, Hinrichs WLJ, et al. NIR spectroscopy for the in-line monitoring of a multicomponent formulation during the entire freeze-drying process. J Pharm Biomed Anal 2014;97:39-46.
Palou A, Cruz J, Blanco M, Larraz R, Frontela J, Bengoechea CM, et al. Characterization of the composition of paraffin waxes on industrial applications. Energy Fuels 2014;28(2):956-963.
Càrdenas V, Blanco M, Alcalà M. Strategies for Selecting the Calibration Set in Pharmaceutical Near Infrared Spectroscopy Analysis. A Comparative Study. J Pharm Innov 2014;9(4):272-281.
Arruabarrena J, Coello J, Maspoch S. Raman spectroscopy as a complementary tool to assess the content uniformity of dosage units in break-scored warfarin tablets. Int J Pharm 2014;465(1-2):299-305.
Publications 2013
Armenta S, De La Guardia M, Alcalà M, Blanco M. Noninvasive double confirmation of cocaine abuse. Anal Chem 2013;85(23):11382-11390.
Alcalà M, Blanco M, Moyano D, Broad NW, O'Brien N, Friedrich D, et al. Qualitative and quantitative pharmaceutical analysis with a novel hand-held miniature near infrared spectrometer. J Near Infrared Spectrosc 2013;21(6):445-457.
Armenta S, Alcalà M, Blanco M, González JM. Ion mobility spectrometry for the simultaneous determination of diacetyl midecamycin and detergents in cleaning validation. J Pharm Biomed Anal 2013;83:265-272.
Rosas JG, Armenta S, Cruz J, Blanco M. A new approach to determine the homogeneity in hyperspectral imaging considering the particle size. Anal Chim Acta 2013;787:173-180.
Rosas JG, Blanco M, Santamaría F, Alcalà M. Assessment of chemometric methods for the non-invasive monitoring of solid blending processes using wireless near infrared spectroscopy. J Near Infrared Spectrosc 2013;21(2):97-106.
Armenta S, Gonzálvez A, Blanco M. Spray nebulization for sample introduction in ion mobility spectrometry. Anal Chim Acta 2013;769:91-99.
Arruabarrena J, Coello J, Maspoch S. NIR reflectance determination of warfarin in a solid preparation commercialized at different API mass proportions. Anal Methods 2013;5(16):3858-3863.
Lucio-Gutiérrez JR, Coello J, Maspoch S. Expeditious identification and semi-quantification of Panax ginseng using near infrared spectral fingerprints and multivariate analysis. Anal Methods 2013;5(4):857-865.
Candela AM, Coello J, Palet C. Doehlert experimental design as a tool to study liquid-liquid systems for the recovery of Uranium (VI) traces. Sep Purif Technol 2013;118:399-405.
Publications 2012
Armenta S, Blanco M. Ion mobility spectrometry for monitoring diamine oxidase activity. Analyst 2012;137(24):5891-5897.
Rosas JG, Blanco M. A criterion for assessing homogeneity distribution in hyperspectral images. Part 2: Application of homogeneity indices to solid pharmaceutical dosage forms. J Pharm Biomed Anal 2012;70:691-699.
Rosas JG, Blanco M. A criterion for assessing homogeneity distribution in hyperspectral images. Part 1: Homogeneity index bases and blending processes. J Pharm Biomed Anal 2012;70:680-690.
Rosas JG, Blanco M, González JM, Alcalà M. Real-time determination of critical quality attributes using near-infrared spectroscopy: A contribution for Process Analytical Technology (PAT). Talanta 2012;97:163-170.
Armenta S, Blanco M. Ion mobility spectrometry as a high-throughput analytical tool in occupational pyrethroid exposure. Anal Bioanal Chem 2012;404(3):635-648.
Blanco M, Peguero A. A new and simple PLS calibration method for NIR spectroscopy. API determination in intact solid formulations. Anal Methods 2012;4(6):1507-1512.
Armenta S, Blanco M. Ion mobility spectrometry: A comprehensive and versatile tool for occupational pharmaceutical exposure assessment. Anal Chem 2012;84(10):4560-4568.
Zamora D, Blanco M. Improving the efficiency of ion mobility spectrometry analyses by using multivariate calibration. Anal Chim Acta 2012;726:50-56.
Zamora D, Blanco M, Bautista M, Mulero R, Mir M. An analytical method for lubricant quality control by NIR spectroscopy. Talanta 2012;89:478-483.
Blanco M, Cueva-Mestanza R, Cruz J. Critical evaluation of methods for end-point determination in pharmaceutical blending processes. Anal Methods 2012;4(9):2694-2703.
Palou A, Cruz J, Blanco M, Tomàs J, De Los Ríos J, Alcalà M. Determination of drug, excipients and coating distribution in pharmaceutical tablets using NIR-CI. J Pharmaceut Analy 2012;2(2):90-97.
Lucio-Gutiérrez JR, Garza-Juárez A, Coello J, Maspoch S, Salazar-Cavazos ML, Salazar-Aranda R, et al. Multi-wavelength high-performance liquid chromatographic fingerprints and chemometrics to predict the antioxidant activity of Turnera diffusa as part of its quality control. J Chromatogr A 2012;1235:68-76.
Arruabarrena J, Coello J, Maspoch S. Enhancing sensitivity and precision on nir reflectance determination of an api at low concentration: Application to an hormonal preparation. J Pharm Biomed Anal 2012;60:59-64.
Lucio-Gutiérrez JR, Coello J, Maspoch S. Enhanced chromatographic fingerprinting of herb materials by multi-wavelength selection and chemometrics. Anal Chim Acta 2012;710:40-49.
Publications 2011
Zamora D, Alcalà M, Blanco M. Determination of trace impurities in cosmetic intermediates by ion mobility spectrometry. Anal Chim Acta 2011;708(1-2):69-74.
Armenta S, Alcala M, Blanco M. A review of recent, unconventional applications of ion mobility spectrometry (IMS). Anal Chim Acta 2011;703(2):114-123.
Armenta S, Blanco M. Pros and cons of benzodiazepines screening in human saliva by ion mobility spectrometry. Anal Bioanal Chem 2011;401(6):1935-1948.
Blanco M, Cueva-Mestanza R, Peguero A. NIR analysis of pharmaceutical samples without reference data: Improving the calibration. Talanta 2011;85(4):2218-2225.
Cruz J, Blanco M. Content uniformity studies in tablets by NIR-CI. J Pharm Biomed Anal 2011;56(2):408-412.
Armenta S, Blanco M. Ion mobility spectrometry: A valuable tool for kinetic studies in enzymology. Anal Chim Acta 2011;685(1):1-8.
Rosas JG, Blanco M, González JM, Alcalá M. Quality by design approach of a pharmaceutical gel manufacturing process, part 1: Determination of the design space. J Pharm Sci 2011;100(10):4432-4441.
Rosas JG, Blanco M, González JM, Alcalá M. Quality by design approach of a pharmaceutical gel manufacturing process, part 2: Near infrared monitoring of composition and physical parameters. J Pharm Sci 2011;100(10):4442-4451.
Franch-Lage F, Amigo JM, Skibsted E, Maspoch S, Coello J. Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging. Int J Pharm 2011;411(1-2):27-35.
Lucio-Gutiérrez JR, Coello J, Maspoch S. Application of near infrared spectral fingerprinting and pattern recognition techniques for fast identification of Eleutherococcus senticosus. Food Res Int 2011;44(2):557-565.
Martí-Aluja I, Ruisánchez I, Cádiz V, Maspoch S, Larrechi MS. Aza-Michael reaction with enone-modified vegetable oils: Evidence of the keto-enolic equilibrium by NIR chemical imaging and evolving factor analysis. Anal Bioanal Chem 2011;399(6):1975-1982.
Publications 2010
Blanco M, Peguero A. Analysis of pharmaceuticals by NIR spectroscopy without a reference method. TrAC Trends Anal Chem 2010;29(10):1127-1136.
Blanco M, Sánchez MJ, Alcalà M. Study of ε-caprolactone polymerization by NIR spectroscopy. Anal Bioanal Chem 2010;397(8):3575-3579.
Blanco M, Peguero A. Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. J Pharm Biomed Anal 2010;52(1):59-65.
Romía MB, Bernárdez MA. Nir Spectroscopy in Pharmaceutical Analysis: Off-Line and At-Line PAT Applications. Process Analytical Technology: Spectroscopic Tools and Implementation Strategies for the Chemical and Pharmaceutical Industries: Second Edition; 2010. p. 463-491.
Blanco M, Cueva-Mestanza R, Peguero A. Controlling individual steps in the production process of paracetamol tablets by use of NIR spectroscopy. J Pharm Biomed Anal 2010;51(4):797-804.
Alcalà M, Blanco M, Bautista M, González JM. On-line monitoring of a granulation process by NIR spectroscopy. J Pharm Sci 2010;99(1):336-345.
Publications 2009
Cruz J, Bautista M, Amigo JM, Blanco M. Nir-chemical imaging study of acetylsalicylic acid in commercial tablets. Talanta 2009;80(2):473-478.
Blanco Romía M, Alcalà Bernàrdez M. Multivariate Calibration for Quantitative Analysis. Infrared Spectroscopy for Food Quality Analysis and Control; 2009. p. 51-82.
Blanco M, Zamora D, Planells J, Mulero R. Analytical control of adjuvants in herbicide formulations by NIR spectroscopy. Anal Bioanal Chem 2009;395(3):839-844.
Blanco M, Zamora D, Mir M, Mulero R. Study of the lipase-catalyzed esterification of stearic acid by glycerol using in-line near-infrared spectroscopy. Ind Eng Chem Res 2009;48(15):6957-6960.
Cairós C, Amigo JM, Watt R, Coello J, Maspoch S. Implementation of enhanced correlation maps in near infrared chemical images: Application in pharmaceutical research. Talanta 2009;79(3):657-664.
Publications 2008
Blanco M, Peguero A. An expeditious method for determining particle size distribution by near infrared spectroscopy: Comparison of PLS2 and ANN models. Talanta 2008;77(2):647-651.
Blanco M, Cruz J, Bautista M. Development of a univariate calibration model for pharmaceutical analysis based on NIR spectra. Anal Bioanal Chem 2008;392(7-8):1367-1372.
Blanco M, Cruz J, Armengol M. Control production of polyester resins by NIR spectroscopy. Microchem J 2008;90(2):118-123.
Blanco M, Bautista M, Alcalà M. API determination by NIR spectroscopy across pharmaceutical production process. AAPS PharmSciTech 2008;9(4):1130-1135.
Amigo JM, Cruz J, Bautista M, Maspoch S, Coello J, Blanco M. Study of pharmaceutical samples by NIR chemical-image and multivariate analysis. TrAC Trends Anal Chem 2008;27(8):696-713.
Blanco M, Alcalá M, Bautista M. Pharmaceutical gel analysis by NIR spectroscopy. Determination of the active principle and low concentration of preservatives. Eur J Pharm Sci 2008;33(4-5):409-414.
Blanco M, Bautista M, Alcalá M. Preparing calibration sets for use in pharmaceutical analysis by NIR spectroscopy. J Pharm Sci 2008;97(3):1236-1245.
Alcalà M, León J, Ropero J, Blanco M, Romañach RJ. Analysis of low content drug tablets by transmission near infrared spectroscopy: Selection of calibration ranges according to multivariate detection and quantitation limits of PLS models. J Pharm Sci 2008;97(12):5318-5327.
Cairos C, Coello J, Maspoch S. Application of representative layer theory to near-infrared reflectance spectra of powdered samples. Appl Spectrosc 2008;62(12):1363-1369.
Amigo JM, Skov T, Bro R, Coello J, Maspoch S. Solving GC-MS problems with PARAFAC2. TrAC Trends Anal Chem 2008;27(8):714-725.
Amigo JM, Surribas A, Coello J, Montesinos JL, Maspoch S, Valero F. On-line parallel factor analysis. A step forward in the monitoring of bioprocesses in real time. Chemometr Intelligent Lab Syst 2008;92(1):44-52.
