Relationship between Physical Activity and Plasma Fibrinogen Concentrations in Adults without Chronic Diseases
Gomez-Marcos, Manuel A. (Universidad de Salamanca. Departamento de Medicina)
Recio Rodríguez, José I. (Centro de Salud La Almedilla (Salamanca, Castella i Lleó))
Patino Alonso, María C. (Universidad de Salamanca. Departamento de Estadística)
Martinez Vizcaino, Vicente (Universidad de Castilla-La Mancha. Centro de Investigación de Atención Social y Sanitaria)
Martín Borràs, Carme (Universitat Ramon Llull. Departament de Ciències de l'Esport)
De la Cal de la Fuente, Aventina (Centro de Salud Casa de Barco (Valladolid, Castella i Lleó))
Sauras Llera, Ines (Centro de Salud Torre Ramona (Saragossa, Aragó))
Sanchez Perez, Álvaro (Osakidetza Servicio Vasco de Salud)
Agudo-Conde, Cristina (Centro de Salud La Almedilla (Salamanca, Castella i Lleó))
Garcia-Ortiz, Luis (Centro de Salud La Almedilla (Salamanca, Castella i Lleó))

Fecha:	2014
Resumen:	Objective: to analyze the relationship between regular physical activity, as assessed by accelerometer and 7-day physical activity recall (PAR), and plasma fibrinogen concentrations. Methods: a cross-sectional study in a previously established cohort of healthy subjects was performed. This study analyzed 1284 subjects who were included in the EVIDENT study (mean age 55. 0±13. 6 years; 60. 90% women). Fibrinogen concentrations were measured in blood plasma. Physical activity was assessed with a 7-day PAR (metabolic equivalents (METs)/hour/week) and GT3X ActiGraph accelerometer (counts/minute) for 7 days. Results: physical exercise, which was evaluated with both an accelerometer (Median: 237. 28 counts/minute) and 7-day PAR (Median: 8 METs/hour/week). Physical activity was negatively correlated with plasma fibrinogen concentrations, which was evaluated by counts/min (r = -0. 100; p<0. 001) and METs/hour/week (r = -0. 162; p<0. 001). In a multiple linear regression analysis, fibrinogen concentrations of the subjects who performed more physical activity (third tertile of count/minute and METs/hour/week) respect to subjects who performed less (first tertile), maintained statistical significance after adjustments for age and others confounders (β = -0. 03; p = 0. 046 and β = -0. 06; p<0. 001, respectively). Conclusions: Physical activity, as assessed by accelerometer and 7-day PAR, was negatively associated with plasma fibrinogen concentrations. This relation is maintained in subjects who performed more exercise even after adjusting for age and other confounders.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Fibrinogen ; Accelerometers ; Blood plasma ; Blood pressure ; Blood counts ; Cholesterol ; Exercise ; Alcohol consumption
Publicado en:	PloS one, Vol. 9 Issue 2 (February 2014) , p. e87954, ISSN 1932-6203

DOI: 10.1371/journal.pone.0087954
PMID: 24498413

7 p, 323.1 KB

El registro aparece en las colecciones:
Artículos > Artículos de investigación
Artículos > Artículos publicados