Novel improvement in iPSCs generation protocols through mouse gametogenesis epigenetic erasure mechanisms
Díaz Pedrosa, Núria
Ibáñez, Elena, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Universitat Autònoma de Barcelona. Facultat de Biociències

Date: 2016
Description: 1 pag.
Abstract: The main goal of this review is to describe gametogenesis epigenetic erasure mechanisms and to propose candidate molecules which can erase remaining epigenetic marks that enhace re-differentiation of cultured induced pluripotent stem cells (iPSCs) into their tissue of origin. For accomplishing this objective, the most representative epigenetic events occurring during gametogenesis are detailed, because those are responsible for erasing parental epigenetic marks. Moreover, early embryonic development is also studied for describing pluripotency establishment. Finally, different epigenetic regulators from the three studied mechanisms are proposed as candidates to improve iPSCs generation protocols.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades. Creative Commons
Language: Anglès.
Studies: Genètica [2500890]
Study plan: Graduat o Graduada en Genètica [833]
Document: bachelorThesis ; Text
Subject: Cèl·lules mare pluripotents induïdes ; Epigenètica ; Epigenetics ; Ipscs ; Induced pluripotent stem cells



1 p, 2.4 MB

The record appears in these collections:
Research literature > Bachelor's degree final project > Biosciences Faculty

 Record created 2016-09-21, last modified 2019-10-02



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