Preserved Error-Monitoring in Borderline Personality Disorder Patients with and without Non-Suicidal Self-Injury Behaviors
Vega Moreno, Daniel (Hospital d'Igualada)
Vilà-Balló, Adrià (Institut d'Investigació Biomèdica de Bellvitge)
Soto Lumbreras, Angel (Hospital d'Igualada)
Amengual, Julià (Institut d'Investigació Biomèdica de Bellvitge)
Ribas i Sabaté, Joan (Hospital d'Igualada)
Torrúbia, Rafael (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Rodríguez Fornells, Antoni (Institut d'Investigació Biomèdica de Bellvitge)
Marco-Pallarés, Josep (Institut d'Investigació Biomèdica de Bellvitge)

Date:	2015
Abstract:	Background: The presence of non-suicidal self-injury acts in Borderline Personality Disorder (BPD) is very prevalent. These behaviors are a public health concern and have become a poorly understood phenomenon in the community. It has been proposed that the commission of non-suicidal self-injury might be related to a failure in the brain network regulating executive functions. Previous studies have shown that BPD patients present an impairment in their capacity to monitor actions and conflicts associated with the performance of certain actions, which suppose an important aspect of cognitive control. Method: We used Event Related Potentials to examine the behavioral and electrophysiological indexes associated with the error monitoring in two BPD outpatients groups (17 patients each) differentiated according to the presence or absence of non-suicidal self-injury behaviors. We also examined 17 age- and intelligence- matched healthy control participants. Results: The three groups did not show significant differences in event-related potentials associated with errors (Error-Related Negativity and Pe) nor in theta power increase following errors. Conclusions: This is the first study investigating the behavioral and electrophysiological error monitoring indexes in BPD patients characterized by their history of non-suicidal self-injury behaviors. Our results show that error monitoring is preserved in BPD patients and suggest that non-suicidal self-injury acts are not related to a dysfunction in the cognitive control mechanisms.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Self harm ; Behavior ; Event-related potentials ; Impulsivity ; Patients ; Cognitive impairment ; Reaction time ; Personality disorders
Published in:	PloS one, Vol. 10, Num. 12 (December 2015) , p. 1-16, ISSN 1932-6203

DOI: 10.1371/journal.pone.0143994
PMID: 26636971

16 p, 2.3 MB

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