Blood pressure values and depression in hypertensive individuals at high cardiovascular risk
Mejia-Lancheros, Cilia (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Estruch, Ramón (Hospital Clínic i Provincial de Barcelona)
Martínez-González, Miguel Angel (Universidad de Navarra)
Salas-Salvadó, Jordi (Hospital Universitari Sant Joan de Reus (Tarragona))
Corella, Dolores (Universitat de València. Departament de Medicina Preventiva i Salut Pública, Ciències de l'Alimentació, Toxicologia i Medicina Legal)
Gómez-Gracia, Enrique (Universidad de Málaga. Departamento de Medicina y Dermatología)
Fiol-Sala, Miquel (Universitat de les Illes Balears. Institut Universitari d'Investigació en Ciències de la Salut)
Fitó, Montse (Institut Hospital del Mar d'Investigacions Mèdiques)
Arós, Fernando (Arabako Unibertsitate Ospitalea (Vitoria, País Basc))
Serra-Majem, Lluis (Universidad de Las Palmas de Gran Canaria)
Pintó, Xavier (Hospital Universitari de Bellvitge)
Basora, Josep (Institut Català de la Salut)
Sorlí, José V (Institut Valencià de la Salut)
Muñoz, Miguel-Angel (Institut Català de la Salut)

Date:	2014
Abstract:	Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. Cross-sectional study, embedded within the PREDIMED clinical trial, of 5954 hypertensive patients with high cardiovascular risk factor profiles. The relationship between blood pressure control and depression was analyzed. A multivariate analysis (logistic and log-linear regression), adjusting for potential confounders (socio-demographic factors, body mass index, lifestyle, diabetes, dyslipidemia, and antihypertensive treatment), was performed. Depressive patients, with and without antidepressant treatment, had better blood pressure control (OR: 1. 28, CI 95%: 1. 06-1. 55, and OR: 1. 30, CI 95%: 1. 03-1. 65, respectively) than non-depressive ones. Regarding blood pressure levels, systolic blood pressure values (mmHg) were found to be lower in both treated and untreated depressive patients (Log coefficient Beta: -1. 59, 95% CI: -0. 50 to -2. 69 and Log coefficient Beta: -3. 49, 95% CI: -2. 10 to -4. 87, respectively). Among hypertensive patients at high cardiovascular risk, the control of blood pressure was better in those diagnosed with depression.
Grants:	Instituto de Salud Carlos III RTIC G03-140 Ministerio de Ciencia e Innovación AGL-200913906-C02
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Hypertension ; Depression ; Blood pressure
Published in:	BMC Cardiovascular disorders, Vol. 14 (august 2014) , ISSN 1471-2261

DOI: 10.1186/1471-2261-14-109
PMID: 25160563

8 p, 370.0 KB

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