Home > Articles > Published articles > Renal Biopsy in Type 2 Diabetic Patients |
Date: | 2015 |
Abstract: | The majority of diabetic patients with renal involvement are not biopsied. Studies evaluating histological findings in renal biopsies performed in diabetic patients have shown that approximately one third of the cases will show pure diabetic nephropathy, one third a non-diabetic condition and another third will show diabetic nephropathy with a superimposed disease. Early diagnosis of treatable non-diabetic diseases in diabetic patients is important to ameliorate renal prognosis. The publication of the International Consensus Document for the classification of type 1 and type 2 diabetes has provided common criteria for the classification of diabetic nephropathy and its utility to stratify risk for renal failure has already been demonstrated in different retrospective studies. The availability of new drugs with the potential to modify the natural history of diabetic nephropathy has raised the question whether renal biopsies may allow a better design of clinical trials aimed to delay the progression of chronic kidney disease in diabetic patients. |
Grants: | Instituto de Salud Carlos III PIE13-00027 Instituto de Salud Carlos III PI14-01383 Instituto de Salud Carlos III REDinREN/12-0021-0013 |
Rights: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. |
Language: | Anglès |
Document: | Article de revisió ; Article ; Versió publicada |
Subject: | Diabetic nephropathy ; Type 2 diabetes ; Kidney biopsy ; Histology |
Published in: | Journal of clinical medicine, Vol. 4 (may 2015) , p. 998-1009, ISSN 2077-0383 |
12 p, 363.1 KB |